Neoadjuvant Lurbinectedin and Preoperative Radiation for Treating Soft Tissue Sarcomas
Conditions: Locally Advanced Soft Tissue Sarcoma Interventions: Drug: Lurbinectedin; Radiation: Radiotherapy; Procedure: Non-investigational surgery Sponsors: University of California, San Francisco; Jazz Pharmaceuticals Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 22, 2024 Category: Research Source Type: clinical trials

Metastatic or Refractory Soft Tissue Sarcomas and Metronomic Cyclophosphamide: Further Assessment of Efficacy and Safety
Conditions: Sarcoma; Soft Tissue Sarcoma Sponsors: Centre Hospitalier Universitaire de Besancon Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 22, 2024 Category: Research Source Type: clinical trials

Superiority Trial Evaluating Digitalized Information Media for Patients With Advanced Sarcomas Receiving Second Line Treatment.
Conditions: Sarcoma Metastatic; Locally Advanced Soft Tissue Sarcoma Interventions: Other: Dematerialized Personalized Care Plan (ePCP) Sponsors: Centre Oscar Lambret; Cancerop ôle Nord Ouest Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 18, 2024 Category: Research Source Type: clinical trials

Fruquintinib-based Treatment for Refractory Bone and Soft Tissue Sarcomas After Several Lines of TKIs' Resistance
Conditions: Refractory Bone and Soft Tissue Sarcomas Interventions: Drug: Fruquintinib Sponsors: Peking University People ' s Hospital Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 11, 2024 Category: Research Source Type: clinical trials

A Clinical Study on Oncolytic Virus Injection (R130) for the Treatment of Advanced Bone and Soft Tissue Tumors
Conditions: Osteosarcoma; Sarcoma; Soft Tissue Sarcoma; Bone Tumor Interventions: Drug: Recombinant oncolytic herpes simplex virus type Ⅰ (R130) Sponsors: Shanghai Yunying Medical Technology; Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 14, 2023 Category: Research Source Type: clinical trials

Pembrolizumab in Combination With Eftilagimod Alpha and Radiotherapy in Neoadjuvant Treatment of Patients With Soft Tissue Sarcoma - EFTISARC-NEO Trial
Conditions: Neoadjuvant; Immunotherapy; Sarcoma,Soft Tissue; Radiation Therapy Interventions: Drug: Pembrolizumab, Eftilagimod alpha Sponsors: Maria Sklodowska-Curie National Research Institute of Oncology; Immutep S.A.S. Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 13, 2023 Category: Research Source Type: clinical trials

Study Assessing the Effects of Early Psychiatric Referral on Mental Health and Quality of Life in People With Sarcoma
Conditions: Sarcoma; Bone Sarcoma; Soft Tissue Sarcoma Interventions: Other: referral to the Memorial Sloan-Kettering Cancer Center (MSK) Department of Psychiatry and Behavioral Sciences. Sponsors: Memorial Sloan Kettering Cancer Center Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 13, 2023 Category: Research Source Type: clinical trials

Clinical Study of VG161 in the Treatment of Advanced Bone and Soft Tissue Sarcoma
Conditions: Sarcoma Interventions: Drug: Recombinant Human IL12/15-PDL1B Oncolytic HSV-1 Injection (Vero Cell) Sponsors: CNBG-Virogin Biotech (Shanghai) Ltd. Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 10, 2023 Category: Research Source Type: clinical trials

Safety and Efficacy of NK510 to Treat Osteosarcoma and Soft Tissue Sarcoma
Conditions: Osteosarcoma; Soft Tissue Sarcoma Interventions: Drug: NK510; Drug: NK510 Sponsors: Base Therapeutics (Shanghai) Co., Ltd.; Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 6, 2023 Category: Research Source Type: clinical trials

Efficacy and Safety Study of Cardunilizumab in Soft Tissue Sarcoma
Conditions: Sarcoma, Soft Tissue Interventions: Drug: Cardunilizumab Sponsors: Xiangya Hospital of Central South University Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 2, 2023 Category: Research Source Type: clinical trials

Selinexor Plus Gemcitabine in Selected Advanced Soft-tissue Sarcoma (SeliSarc)
Conditions: Sarcoma,Soft Tissue Interventions: Drug: Selinexor 20 MG; Drug: Gemcitabine Sponsors: Asociaci ón Europea y Latinoamericana SELNET para la Investigación en Sarcomas Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 2, 2023 Category: Research Source Type: clinical trials

A Study of Surufatinib in the Treatment of Advanced Soft Tissue Sarcoma
Conditions: Soft Tissue Sarcoma Adult Interventions: Drug: Surufatinib Sponsors: Fudan University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 31, 2023 Category: Research Source Type: clinical trials

5-Day Preoperative Radiation for Soft Tissue Sarcoma
Conditions: Soft Tissue Sarcoma Interventions: Radiation: External Beam Radiotherapy Sponsors: Stanford University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 18, 2023 Category: Research Source Type: clinical trials

Targeting MDMD and PD1 in Tumors With Tertiary Lymphoid Structures
Conditions: Adult Soft Tissue Sarcoma; Non Small Cell Lung Cancer; Triple Negative Breast Cancer; Colorectal Cancer; Biliary Tract Cancer Interventions: Drug: Ezabenlimab + BI907828 Sponsors: Institut Bergoni é; Boehringer Ingelheim Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 16, 2023 Category: Research Source Type: clinical trials

PARP Inhibition, Stereotactic Body Radiotherapy and Immunotherapy for Metastatic or Advanced Sarcoma (PRIMA): a Prospective Phase 2 Trial
Conditions: Sarcoma; Sarcoma,Soft Tissue; Sarcoma of Bone Interventions: Combination Product: Camrelizumab and fluzoparib with concurrent stereotactic body radiotherapy (SBRT) Sponsors: Ruijin Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 10, 2023 Category: Research Source Type: clinical trials