Mentored Career Development Award to Promote Faculty Diversity in Biomedical Research (K01 Independent Clinical Trial Not Allowed)
Funding Opportunity RFA-HL-25-009 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity (NOFO) invites applications to enhance the pool of highly trained investigators from diverse backgrounds, including those from groups underrepresented in research areas of interest to the NHLBI. The career development will take place under the guidance of an experienced mentor in the biomedical, behavioral or clinical sciences leading to research independence. It is targeted toward individuals whose basic, clinical, and translational research interests are grounded in the advanced methods and experimental ap...
Source: NIH Funding Opportunities (Notices, PA, RFA) - May 9, 2024 Category: Research Source Type: funding

Mentored Career Development Award to Promote Faculty Diversity in Biomedical Research (K01 Independent Clinical Trial Required)
Funding Opportunity RFA-HL-25-008 from the NIH Guide for Grants and Contracts. Purpose This Notice of Funding Opportunity (NOFO) invites applications to enhance the pool of highly trained investigators from diverse backgrounds, including those from groups underrepresented in research areas of interest to the NHLBI. The career development will take place under the guidance of an experienced mentor in the biomedical, behavioral or clinical sciences leading to research independence. It is targeted toward individuals whose basic, clinical, and translational research interests are grounded in the advanced methods and experim...
Source: NIH Funding Opportunities (Notices, PA, RFA) - May 9, 2024 Category: Research Source Type: funding

NHLBI Outstanding Investigator Award (OIA) (R35 Clinical Trial Optional)
Funding Opportunity RFA-HL-26-002 from the NIH Guide for Grants and Contracts. The purpose of the NHLBI Outstanding Investigator Award (OIA) is to promote scientific productivity and innovation by providing long-term support and increased flexibility to experienced Program Directors/Principal Investigators (PDs/PIs) who are currently PDs/PIs on at least two NHLBI R01-equivalent awards and whose outstanding record of research demonstrates their ability to make major contributions to heart, lung, blood and sleep (HLBS) research. The OIA is intended to support a research program, rather than a research project, by providin...
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 26, 2024 Category: Research Source Type: funding

NHLBI Emerging Investigator Award (EIA) (R35 Clinical Trial Optional)
Funding Opportunity RFA-HL-26-003 from the NIH Guide for Grants and Contracts. The purpose of the NHLBI Emerging Investigator Award (EIA) is to promote scientific productivity and innovation by providing long-term support and increased flexibility to experienced Program Directors/Principal Investigators (PDs/PIs) who are currently PDs/PIs on at least two NHLBI R01-equivalent awards and whose outstanding record of research demonstrates their ability to make major contributions to heart, lung, blood and sleep (HLBS) research. The EIA is intended to support a research program, rather than a research project, by providing t...
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 26, 2024 Category: Research Source Type: funding

Interventions to Reduce Sleep Health Disparities (R01 - Clinical Trials Optional)
The objective of this funding opportunity is to support non-pharmacological interventions to promote sleep health, reduce sleep health disparities, and examine sleep as a modifiable factor to reduce health disparities for other health outcomes among populations that experience health disparities. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 19, 2024 Category: Research Source Type: funding

Optimizing Behavioral Sleep Interventions for Adolescents and Young Adults (R34 Clinical Trial Required)
Funding Opportunity RFA-MH-25-130 from the NIH Guide for Grants and Contracts. NIMH seeks applications for pilot research to adapt, optimize, and test empirically supported behavioral interventions that address common sleep problems in adolescents and young adults with or at risk for a mental health disorder. Pilot trials should be designed to evaluate the feasibility, tolerability, acceptability, safety, and potential effectiveness of the approach in real world settings, and to conduct a preliminary test of the interventions impact on target mechanisms and sleep and mental health outcomes, and to obtain preliminary dat...
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 17, 2024 Category: Research Source Type: funding

NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R61/R33 Clinical Trial Required)
The objective of this funding opportunity is to support investigator-initiated, Phase I clinical trials for diagnostic and therapeutic interventions for heart, lung, blood, and sleep (HLBS) disorders in adults and children. In addition to supporting clinical trial start-up and implementation activities, this FOA will provide support for final stage preclinical activities needed for the implementation of the proposed trial. All the activities proposed in the R61 phase must be directly related to the therapeutic/diagnostic in preparation for the clinical trial. The proposed trial can be single or multisite. This NOFO will ut...
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 2, 2024 Category: Research Source Type: funding

NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R33 CT Required)
The objective of this funding opportunity is to support investigator-initiated, phase I clinical trials for diagnostic and therapeutic interventions for heart, lung, blood, and sleep (HLBS) disorders in adults and children. The proposed trial can be single or multisite. Applicants applying for funding under this NOFO should be ready to initiate the clinical trial within the first quarter of the project period. Discussion, submission, and attainment of applicable regulatory (FDA, DSMB, IRB) approvals, and establishment of drug (and placebo, if applicable) supplies, and any necessary third-party agreements should be establis...
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 1, 2024 Category: Research Source Type: funding

Mechanisms of Cognitive Fluctuations in ADRD Populations (R01 - Clinical Trial Optional)
Funding Opportunity RFA-NS-25-014 from the NIH Guide for Grants and Contracts. "Fluctuating cognition can occur in many types of dementia and is a core clinical feature of Dementia with Lewy Bodies. Cognitive fluctuations can last from seconds to days, are unpredictable (e.g., do not just occur in the evenings, as with sun-downing), and are associated with poor daily functioning for the patient. A number of small studies have suggested that cognitive fluctuations in subjects with dementia may be related to epileptiform discharges and impaired oscillatory activity on EEG, but it is not clear that these are the only facto...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 18, 2024 Category: Research Source Type: funding

Notice of NICHD Withdrawal from Participation in NOT-HL-23-117 "Notice of Special Interest (NOSI): Palliative Care in the Care Continuum among Persons with Serious Heart, Lung, Blood and Sleep (HLBS) Diseases and their Caregivers"
Notice NOT-HD-23-037 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 24, 2023 Category: Research Source Type: funding

NHLBI Program Project Applications (P01 Clinical Trials Optional)
Funding Opportunity PAR-24-065 from the NIH Guide for Grants and Contracts. The National Heart, Lung, and Blood Institute (NHLBI) Program Project Grant (P01) supports research related to fundamental processes and diseases of the heart, blood and lymphatic vessels, lungs, and blood, including transfusion medicine, blood resources, and sleep disorders other programs including implementation science, health disparities, and translation research that address the mission of the Institute. This FOA requires a minimum of three interrelated research projects that investigate a complex biomedical theme or research question. The ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 20, 2023 Category: Research Source Type: funding

NHLBI Clinical Trial Pilot Studies (R34 Clinical Trial Optional)
Funding Opportunity PAR-24-049 from the NIH Guide for Grants and Contracts. This Notice of Funding Opportunity Announcement (NOFO) intends to supports studies that are both necessary and sufficient to inform the planning of a Phase II-IV clinical trial within NHLBI's mission. The NHLBI expects that applications to this NOFO will describe the planned clinical trial and in so doing demonstrate that the proposed (R34) research is scientifically necessary to design or plan the subsequent trial. Furthermore, this NOFO will support research projects that are designed to provide results that will be sufficient to inform the fu...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 3, 2023 Category: Research Source Type: funding

Notice of Special Interest (NOSI): Palliative Care in the Care Continuum among Persons with Serious Heart, Lung, Blood and Sleep (HLBS) Diseases and their Caregivers
Notice NOT-HL-23-117 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - October 19, 2023 Category: Research Source Type: funding

Request for Information (RFI): Exploring the role of Generative AI in enhancing the use of Big Data in Heart, Lung, Blood, and Sleep (HLBS) research.
Notice NOT-HL-23-097 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - October 3, 2023 Category: Research Source Type: funding

Validating digital health technologies for monitoring biomarkers in ADRD clinical trials (R61/R33 - Clinical Trials Optional)
Funding Opportunity RFA-NS-24-026 from the NIH Guide for Grants and Contracts. The goal of this RFA is to enable partnerships between academics and companies that make wearable devices to validate their digital health technologies (DHTs) as digital monitoring biomarkers in ADRD populations. Applications will be required to optimize their DHTs in diverse patient populations from two or more early stage clinically diagnosed ADRD. Studies must demonstrate the accuracy of the digital markers to differentiate clinically meaningful features (such as sleep stage) and establish the longitudinal relationship between the features...
Source: NIH Funding Opportunities (Notices, PA, RFA) - August 1, 2023 Category: Research Source Type: funding