Correlates of Impairment and Growth in Families of Young Autistic Children
J Autism Dev Disord. 2024 Apr 16. doi: 10.1007/s10803-024-06339-w. Online ahead of print.ABSTRACTThe purpose of this project was to investigate potential correlates of family life impairment in families of young autistic children. This project incorporated measures of specific child and parent challenges in addition to a commonly used unidimensional measure of autism characteristics. In this way, we could assess whether such challenges explain variance in family life impairment, and whether their inclusion diminish associations between autism characteristics and family life impairment. Cross-sectional data were collected f...
Source: Journal of Autism and Developmental Disorders - April 16, 2024 Category: Psychiatry Authors: Kristen T MacKenzie Mario J Crown Jessie B Northrup Elizabeth Rutenberg Amy G Hartman Carla A Mazefsky Source Type: research
Functional therapy and adenotonsillectomy clinical trial for class II malocclusion (FACT-II): protocol for a randomised controlled trial
This study is approved by the Ethics Committee of the School and Hospital of Stomatology, Wuhan University (no. 2022-D07). The research findings will be faithfully disseminated through scientific conferences or published articles.
Trial registration number
ChiCTR2200061703 (https://www.chictr.org.cn). (Source: BMJ Open)
Source: BMJ Open - April 16, 2024 Category: General Medicine Authors: Guo, F., Lv, C., Tang, B., Lin, L., Zhang, C., Zheng, J., Zhao, T., He, H. Tags: Open access, Dentistry and oral medicine Source Type: research
Elevated periodic limb movement index is associated with hypoxemia in children with early onset scoliosis
ConclusionThe study suggests that children with early onset scoliosis have higher frequency of periodic limb movements during sleep, and these may be correlated with increased arousal and with hypoxemia. (Source: Sleep and Breathing)
Source: Sleep and Breathing - April 16, 2024 Category: Respiratory Medicine Source Type: research
Circadian misalignment proxies, BMI, and chronic conditions: the role for weekday to weekend sleep differences
ConclusionsOur findings, which demonstrate that even a slight weekend sleep extension and variability of just 1 h is associated with higher values of BMI, suggest incorporating measures for sleep consistency and regularity into clinical protocols and public health guidelines to prevent and treat obesity and related diseases. (Source: Sleep and Breathing)
Source: Sleep and Breathing - April 16, 2024 Category: Respiratory Medicine Source Type: research
Adult ADHD Linked to Later Lewy Body Disease, Cognitive Impairment
Adults with attention-deficit/hyperactivity disorder (ADHD) may be at increased risk of dementia and cognitive impairment compared with those without ADHD, according to areport in theAmerican Journal of Geriatric Psychiatry. Adults with ADHD seem particularly susceptible to dementia associated with Lewy body disease, a disorder characterized by abnormal deposits of proteins called Lewy bodies in the brain that results in various forms of cognitive impairment, delirium-like symptoms, Parkinson ’s-like movement problems, and hallucinations.“Determining whether there is an association between ADHD and subsequent conversio...
Source: Psychiatr News - April 15, 2024 Category: Psychiatry Tags: ADHD attention deficit hyperactivity disorder cognitive impairment dementia hallucinations Lewy bodies Parkinsons Source Type: research
Mental Health and Quality of Life in Chronic Kidney Disease Patients with Mild-to-Moderate Depression: A Retrospective Cohort Study of Mindfulness-Based Stress Reduction Therapy
CONCLUSION: MBSR can improve the mental health, sleep quality, and quality of life of CKD patients with mild-to-moderate depression, and improve psychological resilience and mindfulness.PMID:38622007 | DOI:10.62641/aep.v52i2.1600 (Source: Actas Espanolas de Psiquiatria)
Source: Actas Espanolas de Psiquiatria - April 15, 2024 Category: Psychiatry Authors: Xiumei Li Wei Gao Jie Yu Yanling Mao Haihong Gu Fang Li Dongmei Ren Source Type: research
Orexinergic Receptor Antagonists as a New Therapeutic Target to Overcome Limitations of Current Pharmacological Treatment of Insomnia Disorder
This study reviews the benefits and risks of current pharmacological treatments for insomnia, with special reference to the orexinergic system as a novel therapeutic target for treatment. The prescription of GABAergic mechanism enhancers (benzodiazepine (BZD) and "Z drugs") has shown efficacy in short-term insomnia treatment (less than 4 weeks), however, concerns arise regarding their long-term effectiveness, unfavorable tolerability and safety profiles, including the potential for dependency. Drugs with antihistamine properties, including certain antidepressants and antipsychotics, exhibit short-term efficacy but have doc...
Source: Actas Espanolas de Psiquiatria - April 15, 2024 Category: Psychiatry Authors: Cecilio Álamo Jer ónimo Sáiz Ruiz Cristina Zaragoz á Arnáez Source Type: research
Clinical prediction of opioid use disorder in chronic pain patients: a cohort-retrospective study with a pharmacogenetic approach
CONCLUSIONS: Functional polymorphisms related to OPRM1 variant and CYP2D6 phenotypes may predict a higher OUD risk. Established risk factors such as young age, elevated MEDD and lower incomes were identified. A predictive model is expected to be implemented in clinical setting among CNCP patients under long-term opioids use.PMID:38619184 | DOI:10.23736/S0375-9393.24.17864-9 (Source: Minerva Anestesiologica)
Source: Minerva Anestesiologica - April 15, 2024 Category: Anesthesiology Authors: M ónica Escorial Javier Muriel Laura Agull ó Thomas Zandonai C ésar Margarit Domingo Morales Ana M Peir ó Source Type: research
Midlife diseases of despair and cardiometabolic risk: testing shared origins in adolescent psychopathology
CONCLUSIONS: Adolescent psychopathology precedes both diseases of despair and cardiometabolic risk. Prevention and treatment of psychopathology may mitigate multiple causes of poor midlife health, reducing premature mortality.PMID:38618989 | DOI:10.1017/S0033291724000916 (Source: Psychological Medicine)
Source: Psychological Medicine - April 15, 2024 Category: Psychiatry Authors: Kallisse R Dent Grace M Brennan Lara Khalifeh Leah S Richmond-Rakerd Source Type: research
Investigating a clinically informed sleep disturbance threshold for physical and mental health among Gulf War Illness veterans
CONCLUSIONS: Disturbed sleep was associated with measures of pain, fatigue, and cognitive health. Our results suggest that a previously determined clinical threshold for clinically disturbed sleep is useful when examining the health status of the study population. Given that GWI is associated with elevated PSQI scores and a high frequency of disturbed sleep, cutoffs determining sleep health should be sensitive to population exposures and health history to improve interpretability.PMID:38616799 | PMC:PMC11015895 | DOI:10.1093/sleepadvances/zpae018 (Source: Adv Data)
Source: Adv Data - April 15, 2024 Category: Epidemiology Authors: Nathaniel Allen Lucas Crock Timothy Chun Matthew J Reinhard Source Type: research
Pulmonology: What You May Have Missed in 2023
Ann Intern Med. 2024 Apr 16. doi: 10.7326/M24-0613. Online ahead of print.ABSTRACTThe field of pulmonology saw significant advances in 2023. The publications highlighted in this article address advances and changes in practice related to asthma, chronic obstructive pulmonary disease (COPD), interstitial lung disease, pleural disorders, and sleep-disordered breathing. One article reviews data examining the efficacy of vaccination against respiratory syncytial virus, a respiratory viral illness that has had devastating effects globally. Four studies evaluate the role of various therapies in COPD, including dupilumab, ensifen...
Source: Annals of Internal Medicine - April 15, 2024 Category: Internal Medicine Authors: Aram Karkar Sana Khan Rebecca O'Leary Albina Tyker Michael Unger Source Type: research
Sleep and Autism: Current Research, Clinical Assessment, and Treatment Strategies
FOCUS,Volume 22, Issue 2, Page 162-169, Spring 2024. (Source: FOCUS)
Source: FOCUS - April 15, 2024 Category: Psychiatry Authors: Annette Estes Arianna Hillman Maida Lynn Chen Source Type: research
LSD increases sleep duration the night after microdosing
Translational Psychiatry, Published online: 15 April 2024; doi:10.1038/s41398-024-02900-4LSD increases sleep duration the night after microdosing (Source: Translational Psychiatry)
Source: Translational Psychiatry - April 15, 2024 Category: Psychiatry Authors: Nathan Allen Aron Jeremiah Robin Murphy Rachael Sumner Anna Forsyth Nicholas Hoeh David B. Menkes William Evans Suresh Muthukumaraswamy Frederick Sundram Partha Roop Source Type: research
Supporting athletes during a challenging situation: recommendations from a global insight of COVID-19 home-based training experience
ConclusionsBoth male and female athletes, particularly those of higher levels, displayed some adaptalibity during the COVID-19 lockdown, employing innovative approaches and technology for training. Many athletes implemented load monitoring, recovery, and attentive of injury prevention, while optimizing their sleep quality and quantity. Athletes demonstrated their abilities to navigate challenges, and utilized different coping strategies in response to the lockdown ’s constraints. (Source: BMC Sports Science, Medicine and Rehabilitation)
Source: BMC Sports Science, Medicine and Rehabilitation - April 15, 2024 Category: Sports Medicine Source Type: research
Influence of Eat, Sleep, and Console on Infants Pharmacologically Treated for Opioid Withdrawal
This randomized clinical trial examines data for infants pharmacologically treated for neonatal opioid withdrawal in a subgroup analysis to evaluate differences in opioid exposure and length of hospital stay comparing a function-based care approach vs usual care. (Source: JAMA Pediatrics)
Source: JAMA Pediatrics - April 15, 2024 Category: Pediatrics Source Type: research
