A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy
Conditions: Advanced Cancer; Advanced Solid Tumor; Melanoma; Metastasis; Pleural Mesothelioma; Renal Cell Carcinoma; MSI-High; Mismatch Repair Deficiency; Colorectal Cancer; Hepatocellular Carcinoma; Hepatocellular Cancer; Renal Cell Cancer; Kidney Cancer; Skin Cancer; Non Small Cell Lung Cancer; NSCLC; Anaplastic Lymphoma Kinase Genomic Tumor Aberrations; ALK Genomic Tumor Aberrations Interventions: Drug: Alintegimod; Drug: Ipilimumab; Drug: Nivolumab Sponsors: 7 Hills Pharma, LLC Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 12, 2024 Category: Research Source Type: clinical trials

Topical Tretinoin Prophylaxis for Anti-EGFR Induced Skin Toxicity in Metastatic Colorectal Cancer
Conditions: Metastatic Colon Cancer; Metastatic Rectum Cancer Interventions: Drug: Topical Tretinoin; Other: Placebo Sponsors: University of Utah Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 10, 2024 Category: Research Source Type: clinical trials

Enhancing Fluid Transfer Through the Skin, by Increased Sweat Rate, on Hemodialysis Patients
Conditions: Acute Kidney Failure; Chronic Kidney Diseases Interventions: Device: The AquaPass System Sponsors: AquaPass Medical Ltd. Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 10, 2024 Category: Research Source Type: clinical trials

Australasian Malignant PLeural Effusion (AMPLE)-4 trial: study protocol for a multi-centre randomised trial of topical antibiotics prophylaxis for infections of indwelling pleural catheters
DiscussionResults from this trial will determine the efficacy of mupirocin prophylaxis in patients who require IPC for MPE. It will provide data on infection rates, microbiology, and potentially infection pathways associated with IPC-related infections.Ethics and disseminationSir Charles Gairdner and Osborne Park Health Care Group Human Research Ethics Committee has approved the study (RGS0000005920). Results will be published in peer-reviewed journals and presented at scientific conferences.Trial registrationAustralia New Zealand Clinical Trial Registry ACTRN12623000253606. Registered on 9 March 2023. (Source: Trials)
Source: Trials - April 10, 2024 Category: Research Source Type: clinical trials

Scalpel Versus Diathermy in Transverse Abdominal Skin Incision During Cesarean Section
Conditions: Skin Wound Interventions: Other: Skin incision in Cesarean Section by Diathermy; Other: Skin incision in Cesarean Section by Scalpel Sponsors: Cairo University Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 8, 2024 Category: Research Source Type: clinical trials

Evaluation of the Effects of a Biostimulator and Dermal Fillers for Cheek Augmentation and Contour Deficiencies
Conditions: Photoaging; Weight Loss; Skin Laxity; Photodamaged Skin; Volume Deficiency of the Midface Interventions: Device: Sculptra treatment; Device: Restylane Treatment Sponsors: Galderma R&D Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 8, 2024 Category: Research Source Type: clinical trials

Abrocitinib Taiwan Treatment Pattern and Real World Study in ATopiC Dermatitis (ATTRACT Registry)
Conditions: Dermatitis, Atopic; Dermatitis; Eczema; Skin Diseases; Immune System Diseases; Janus Kinase Inhibitors Sponsors: Pfizer Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 8, 2024 Category: Research Source Type: clinical trials

Safety And Efficacy Investigation Of The Effects Of ClearLift Q-Switched Nd:Yag 1064nm Laser Module In The Treatment Of Facial Skin Wrinkles
Conditions: Facial Skin Wrinkles Interventions: Device: Alma Harmony Sponsors: Alma Lasers Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 5, 2024 Category: Research Source Type: clinical trials

Dermatoscopy Guided Resection for Skin Cancer
Conditions: Basal Cell Carcinoma; Cutaneous Squamous Cell Carcinoma; Surgical Margin Interventions: Device: Dermatoscopy Sponsors: Region Örebro County Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 2, 2024 Category: Research Source Type: clinical trials

A single-center, open-labeled, randomized, 6-month, parallel-group study to assess the safety and efficacy of allogeneic cultured keratinocyte sheet transplantation for deep second-degree burn wounds: rationale and design of phase I/II clinical trial
This study will explain the design and rationale of a cellular-based skin substitute for the first time in Iran. In addition, this work proposes this product being registered as an off-the-shelf product for burn wound management in the country.Trial registrationIranian Registry of Clinical Trials (IRCT) IRCT20080728001031N31, 2022-04-23 for phase I and IRCT20080728001031N36,  2024-03-15 for phase II. (Source: Trials)
Source: Trials - April 1, 2024 Category: Research Source Type: clinical trials

In Vivo Evaluation of NC65 - Vita D-Light SKIN ADAPTOGEN AND SEBUM BALANCE EFFICACY
Conditions: SKIN ADAPTOGEN AND SEBUM BALANCE EFFICACY Interventions: Other: Corthellus Shiitake(Mushroom) Extract; Other: Placebo Sponsors: Ritamaria Di Lorenzo Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 29, 2024 Category: Research Source Type: clinical trials

Pre-marketing Clinical Trial to Evaluate the Safety and Efficacy of the Filler of Hyaluronic Acid Recombinant Collagen
Conditions: Wrinkle; Scar; Laxity; Skin Interventions: Device: Karisma Sponsors: Taumedika s.r.l.; Nextrasearch S.r.l.s. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 28, 2024 Category: Research Source Type: clinical trials

Evaluation of the Effects of Cross Linking on the Biomechanical Characteristics of Skin Samples From Patients With Classic or Hypermobile Ehlers-Danlos Syndrome
Conditions: Ehlers-Danlos Syndrome Interventions: Procedure: skin biopsy Sponsors: GCS Ramsay Sant é pour l ' Enseignement et la Recherche Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 28, 2024 Category: Research Source Type: clinical trials

Reduction in Symptoms After Laser Therapy With Acorn aHFS
Conditions: Skin Aging Interventions: Other: autologous hair follicle derived secretome Sponsors: Acorn Biolabs Inc. Enrolling by invitation (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 28, 2024 Category: Research Source Type: clinical trials

4-aminopyridine for Skin Wound Healing
Conditions: Wounds; Wound of Skin; Wound Heal; Wounds and Injuries Interventions: Drug: 4-Aminopyridine; Other: Placebo Sponsors: John Elfar Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 27, 2024 Category: Research Source Type: clinical trials