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Testing the Combination of Two Anticancer Drugs M1774 (Tuvusertib) and Avelumab to Evaluate Their Safety and Effectiveness in Treating Merkel Cell Skin Cancer, MATRiX Trial
Conditions:   Clinical Stage III Merkel Cell Carcinoma AJCC v8;   Clinical Stage IV Merkel Cell Carcinoma AJCC v8;   Locally Advanced Merkel Cell Carcinoma;   Metastatic Merkel Cell Carcinoma;   Refractory Merkel Cell Carcinoma;   Unresectable Merkel Cell Carcinoma Interventions:   Drug: Avelumab;   Procedure: Biopsy;   Procedure: Biospecimen Collection;   Procedure: Computed Tomography;   Procedure: Magnetic Resonance Imaging;   Procedure: Positron Emission Tomography;   Drug: Tuvusertib Sponsor:   National Cancer Institute (NCI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - July 17, 2023 Category: Research Source Type: clinical trials

Versatile Ampification Single-Molecule Detection in Liquid Biopsy
Conditions:   Liquid Biopsy;   Melanoma (Skin);   Melanoma Stage III;   Melanoma Stage IV;   BRAF V600E Intervention:   Device: Affinity Mediated Transport Amplification (AMT) Sponsor:   Regina Elena Cancer Institute Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - July 11, 2023 Category: Research Source Type: clinical trials