Perampanel for the Reduction of Seizure Frequency in Patients With High-grade Glioma and Focal Epilepsy
Conditions:   Intractable Epilepsy;   Malignant Glioma;   Seizure Disorder Interventions:   Drug: Phenobarbital, Phenytoin, Carbamazepine, Valproate, Gabapentin, Pregabalin, Lamotrigine, Topiramate, Leviteracetam, Lacosamide, Zonisamide, Clobazam, Oxcarbezepine, Rufinamide;   Drug: Perampanel;   Other: Quality-of-Life Assessment;   Other: Questionnaire Administration Sponsors:   Mayo Clinic;   National Cancer Institute (NCI) Not yet recruiting (Source:
Source: - December 2, 2020 Category: Research Source Type: clinical trials

Safety Study of Rufinamide Given as an add-on Therapy to Treat Patients With Seizures
Condition:   Refractory Partial Seizures Intervention:   Drug: Rufinamide Sponsor:   University of South Alabama Withdrawn (Source:
Source: - September 22, 2020 Category: Research Source Type: clinical trials