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Preface
Prog Brain Res. 2023;280:xi. doi: 10.1016/S0079-6123(23)00090-0.NO ABSTRACTPMID:37714575 | DOI:10.1016/S0079-6123(23)00090-0
Source: Brain Research - September 15, 2023 Category: Neurology Authors: Tal Dotan Ben-Soussan Joseph Glicksohn Narayanan Srinivasan Source Type: research

Moving through silence in dance: A neural perspective
Prog Brain Res. 2023;280:89-101. doi: 10.1016/bs.pbr.2022.12.009. Epub 2023 Apr 10.ABSTRACTThe word "silence" typically refers to the auditory modality, signifying an absence of sound or noise, being quiet. One may then ask: could we attribute the notion of silence to the domain of dance, e.g., when a movement is absent and the dancer stops moving? Is it at all useful to think in terms of silence when referring to dance? In this chapter, my exploration of these questions is based on recent studies in brain research, which demonstrate the remarkable facility of specific regions in the human brain to perceive visually referr...
Source: Brain Research - September 15, 2023 Category: Neurology Authors: Vered Aviv Source Type: research

Cessations of consciousness in meditation: Advancing a scientific understanding of nirodha sam āpatti
Prog Brain Res. 2023;280:61-87. doi: 10.1016/bs.pbr.2022.12.007. Epub 2023 Apr 24.ABSTRACTAbsence of consciousness can occur due to a concussion, anesthetization, intoxication, epileptic seizure, or other fainting/syncope episode caused by lack of blood flow to the brain. However, some meditation practitioners also report that it is possible to undergo a total absence of consciousness during meditation, lasting up to 7 days, and that these "cessations" can be consistently induced. One form of extended cessation (i.e., nirodha samāpatti) is thought to be different from sleep because practitioners are said to be completely ...
Source: Brain Research - September 15, 2023 Category: Neurology Authors: Ruben E Laukkonen Matthew D Sacchet Henk Barendregt Kathryn J Devaney Avijit Chowdhury Heleen A Slagter Source Type: research

Conscious entry into sleep: Yoga Nidra and accessing subtler states of consciousness
Prog Brain Res. 2023;280:43-60. doi: 10.1016/bs.pbr.2022.12.012. Epub 2023 Feb 1.ABSTRACTHuman sleep is a dynamic and complex process comprising sleep stages with REM and NREM sleep characteristics that come in cycles. During sleep, there is a loss of responsiveness or a perceptual loss of conscious awareness with increasing thresholds for wakefulness as sleep progresses. There are brief bursts of wakefulness or Wake After Sleep Onset (WASO) throughout a nocturnal sleep. Conscious experience during nocturnal sleep is known to occur during lucid dreaming when one is aware during dreams when the dream is occurring. Most cult...
Source: Brain Research - September 15, 2023 Category: Neurology Authors: Prakash Chandra Kavi Source Type: research

The psychophysiology of "covert" goal-directed behavior
Prog Brain Res. 2023;280:17-42. doi: 10.1016/bs.pbr.2023.01.006. Epub 2023 Mar 9.ABSTRACTCovert behavior is defined as behavior that is not directly visible and is thus comparable to a type of behavioral silence that requires modern psychophysiological techniques to reveal. Goal-directed behavior is teleologically purposive. Fundamentally, there are two approaches to accounting for purposeful behavior. One is the cybernetic approach, which views behavior as homeostatic and largely reflexive. The other one views behavior as a cognitive process that involves an interaction between neural events representing the previous expe...
Source: Brain Research - September 15, 2023 Category: Neurology Authors: Giuseppe Augusto Chiarenza Source Type: research

Silence and its effects on the autonomic nervous system: A systematic review
Prog Brain Res. 2023;280:103-144. doi: 10.1016/bs.pbr.2023.08.001. Epub 2023 Sep 1.ABSTRACTThis systematic review explores the influence of silence on the autonomic nervous system. The Polyvagal Theory has been used as a reference model to describe the autonomic nervous system by explaining its role in emotional regulation, social engagement, and adaptive physiological responses. PubMed, Scopus, PsycInfo, EMBASE, and Google Scholar were systematically searched up until July 2023 for relevant studies. The literature search yielded 511 results, and 37 studies were eventually included in this review. Silence affects the auton...
Source: Brain Research - September 15, 2023 Category: Neurology Authors: Davide Donelli Davide Lazzeroni Matteo Rizzato Michele Antonelli Source Type: research

The causal influence of conscious engagement on photonic behavior: A review of the mind-matter interaction
Prog Brain Res. 2023;280:1-16. doi: 10.1016/bs.pbr.2023.03.005. Epub 2023 Apr 11.ABSTRACTThe well-known, quantum physics "double-slit" experiment was the first demonstration of wave-particle duality of light-photons naturally behave like waves, but once they are registered by a conscious observer they switch to behaving like particles. In recent years, a new avenue of research has reported a psychophysical interaction occurring when focused attention was employed in the double-slit experiment. In this context, the act of focusing attention to photons passing through the double-slit appears to collapse their wave function t...
Source: Brain Research - September 15, 2023 Category: Neurology Authors: Teodora Milojevi ć Mark A Elliott Source Type: research

Alterations of learning and memory are accompanied by alterations in the expression of 5-HT receptors, glucocorticoid receptor and brain-derived neurotrophic factor in different brain regions of an animal model of depression generated by neonatally male treatment with clomipramine in male rats
Behav Brain Res. 2023 Sep 14;455:114664. doi: 10.1016/j.bbr.2023.114664. Online ahead of print.ABSTRACTDepressive illness has been associated with impaired cognitive processes accompanied by reduced neurotrophin levels, especially brain-derived neurotrophic factor (BDNF), and dysfunctions in the hypothalamic-pituitary-adrenal (HPA) axis. In addition, depression is characterized by a decreased functioning of the serotonergic system due to changes in the activity or expression of its receptors including, most significantly, 5-HT1A, 5-HT2A, and 5-HT3 in brain regions that regulate mood, emotions, and memory, such as the prefr...
Source: Brain Research - September 15, 2023 Category: Neurology Authors: Ofelia Lim ón-Morales Kenia Morales-Quintero Marcela Arteaga-Silva Tania Molina-Jim énez Marco Cerb ón Herlinda Bonilla-Jaime Source Type: research

40Hz electroacupuncture relieves the memory dysfunction of 5xFAD mice by regulating neuronal electrical activity
Brain Res. 2023 Sep 13:148576. doi: 10.1016/j.brainres.2023.148576. Online ahead of print.ABSTRACTIn this investigation, we probed the impacts of 40Hz Electroacupuncture (EA) on the cognitive function and brain activity in 5xFAD mice. Three groups of mice were constituted: the Model group of 5xFAD mice, the Wild Type (WT) group of littermate controls, and the EA group of 5xFAD mice subjected to EA treatment. Behavioral tests were conducted to evaluate memory function and anxiety levels, while the presence of Aβ plaques were detected via immunostaining, and neuronal activity was measured using multichannel recordings. Our ...
Source: Brain Research - September 15, 2023 Category: Neurology Authors: Jifei Miao Xiaoming Liu Jiao Lan Source Type: research

Activation of adenosine A < sub > 1 < /sub > receptor potentiates metabotropic glutamate receptor 1-mediated Ca < sup > 2+ < /sup > mobilization in the rat hippocampal marginal zone
In this study, potentiation of the mGluR1-mediated response by A1R activation was demonstrated in hippocampal CR cells. Fluorescence imaging revealed that the application of A1R agonists intensified mGluR1-induced elevation of intracellular Ca2+ concentration ([Ca2+]i). Activation of A1R did not change [Ca2+]i. The potentiated responses were independent of extracellular Ca2+ and prevented by the Gi inhibitor. The potentiation of mGluR1-induced [Ca2+]i. elevation was also enhanced by mGluR2/3 activation. These results suggest that mGluR1 and A1R cooperatively influence postnatal hippocampal development by facilitating Ca2+ ...
Source: Brain Research - September 15, 2023 Category: Neurology Authors: Megumi Taketo Source Type: research

Cognitive-exercise dual-task intervention ameliorates cognitive decline in natural aging rats via inhibiting the promotion of LncRNA NEAT1/miR-124-3p on caveolin-1-PI3K/Akt/GSK3 β Pathway
This study aimed to investigate the effects of CEDI and the role of regulation of the lncRNA NEAT1/miR-124-3p on the caveolin-1-PI3K/Akt/GSK3β pathway in CEDI improving cognitive function. Forty 18-month-old natural aging rats were randomly assigned to four groups: exercise training group, cognitive training group, CEDI group, and aging control group, and underwent 12 weeks of intervention. A novel object recognition test was performed to determine the cognitive function, and the hippocampus was separated three days after the behavioral tests for further molecular detection. In an in vitro study, the mouse hippocampal neu...
Source: Brain Research - September 15, 2023 Category: Neurology Authors: Tiancong Li Xue Tao Ruifeng Sun Conglin Han Xiaoling Li Ziman Zhu Wenshan Li Peiling Huang Weijun Gong Source Type: research

MicroRNA-125a-3p modulate amyloid β-protein through the MAPK pathway in Alzheimer's disease
CONCLUSION: Our study indicates that targeting miR-125a-3p may be an applicable therapy for AD in the future. However, more in vitro and in vivo studies with more samples are needed to confirm these results.PMID:37711111 | DOI:10.2174/1567205020666230913105811
Source: Current Alzheimer Research - September 15, 2023 Category: Neurology Authors: Xi-Chen Zhu Meng-Zhuo Zhu Jing Lu Qing-Yu Yao Jia-Wei Hu Wen-Jun Long Sha-Sha Ruan Wen-Zhuo Dai Rong Li Source Type: research

Early Detection of Dementia using Risk Classification in MCI: Outcomes of Shanghai Mild Cognitive Impairment Cohort Study
CONCLUSION: A simple risk classification using the rt. HV and neuropsychological test scores, including those from the ADAS-Cog-C and PACC, could be a practicable and efficient approach to identifying individuals at risk of all-cause dementia.PMID:37711110 | DOI:10.2174/1567205020666230914161034
Source: Current Alzheimer Research - September 15, 2023 Category: Neurology Authors: Bin Zhou Qianhua Zhao Shinsuke Kojima Ding Ding Satoshi Higashide Masanori Fukushima Zhen Hong Source Type: research

Neurological presentation of profound hypothyroidism
Pract Neurol. 2023 Sep 15:pn-2023-003859. doi: 10.1136/pn-2023-003859. Online ahead of print.NO ABSTRACTPMID:37714702 | DOI:10.1136/pn-2023-003859
Source: Practical Neurology - September 15, 2023 Category: Neurology Authors: Christopher Paisey Gurjit Chohan Source Type: research

Alterations of learning and memory are accompanied by alterations in the expression of 5-HT receptors, glucocorticoid receptor and brain-derived neurotrophic factor in different brain regions of an animal model of depression generated by neonatally male treatment with clomipramine in male rats
Behav Brain Res. 2023 Sep 14;455:114664. doi: 10.1016/j.bbr.2023.114664. Online ahead of print.ABSTRACTDepressive illness has been associated with impaired cognitive processes accompanied by reduced neurotrophin levels, especially brain-derived neurotrophic factor (BDNF), and dysfunctions in the hypothalamic-pituitary-adrenal (HPA) axis. In addition, depression is characterized by a decreased functioning of the serotonergic system due to changes in the activity or expression of its receptors including, most significantly, 5-HT1A, 5-HT2A, and 5-HT3 in brain regions that regulate mood, emotions, and memory, such as the prefr...
Source: Behavioural Brain Research - September 15, 2023 Category: Neurology Authors: Ofelia Lim ón-Morales Kenia Morales-Quintero Marcela Arteaga-Silva Tania Molina-Jim énez Marco Cerb ón Herlinda Bonilla-Jaime Source Type: research