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Lower-extremity Dynamometry as a Novel Outcome Measure in a Double-blind, Placebo-controlled, Feasibility Trial of Intravenous Immunoglobulin (IVIG) for HIV-associated Myelopathy
Conclusion: We conclude that an adequately powered clinical trial of IVIG for HIVM would likely require a prolonged recruitment period and multiple participating sites. Lower limb dynamometry is a useful outcome measure for HIVM, which might also be useful in other HIV-related gait disorders. KEYWORDS: Dynamometry, intravenous immunoglobulin (IVIG), human immunodeficiency virus (HIV), myelopathy INTRODUCTION Human immunodeficiency virus (HIV)-associated myelopathy (HIVM) is a rare but well-described neurologic complication of HIV; it was first described early in the acquired immunodeficiency syndrome (AIDS) epidemic, and i...
Source: Innovations in Clinical Neuroscience - February 1, 2018 Category: Neuroscience Authors: ICN Online Editor Tags: Assessment Tools Current Issue Demyelinating Disease Movement Disorders Neurodegenerative Disease Neurology Original Research Primary Care Technology Trial Methodology Dynamometry human immunodeficiency virus (HIV) intravenous immu Source Type: research

A cloudy story: Guillain–Barré syndrome concealed by a spontaneous intracerebral haemorrhage
We present a case of Guillain–Barré syndrome (GBS), probably associated with influenza vaccine, occurring in a patient some days after a spontaneous haemorrhagic stroke. A 79-year-old woman was admitted to the neurosurgery department after a sudden severe headache, dizziness, and progressive generalised weakness. She had a history of hypertension and paroxysmal atrial fibrillation in dicumarolic therapy. Head CT scan showed a haemorrhagic stroke in left cerebellum, with compression on the fourth ventricle.
Source: Clinical Neurophysiology - October 22, 2012 Category: Neuroscience Authors: V. Mantero, L. De Toni Franceschini, L. Abate, F. Villa, A. Patruno, S. Jann, G. Citerio Tags: Letters to the Editor Source Type: research