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Neuro-Ophthalmic Visual Impairment in the Setting of COVID-19
We describe and elaborate on mechanisms of disease, including para-infectious inflammation, hypercoagulability, endothelial damage, and direct neurotropic viral invasion. Despite global vaccination programs, new variants of COVID-19 continue to pose an international threat, and patients with rare neuro-ophthalmic complications are likely to continue to present for care.Afferent complications from COVID-19 include homonymous visual field loss, with or without higher cortical visual syndromes, resulting from stroke, intracerebral hemorrhage, or posterior reversible leukoencephalopathy. Optic neuritis has frequently been repo...
Source: Seminars in Neurology - June 13, 2023 Category: Neurology Authors: Dinkin, Marc Sathi, Swetha Tags: Review Article Source Type: research

Observational Study of Patients Hospitalized With Neurologic Events After SARS-CoV-2 Vaccination, December 2020-June 2021
Discussion All cases in this study were determined to have at least 1 risk factor and/or known etiology accounting for their neurologic syndromes. Our comprehensive clinical review of these cases supports the safety of mRNA COVID-19 vaccines.
Source: Neurology Clinical Practice - May 25, 2023 Category: Neurology Authors: Kim, C. Y., McNeill, E. N., Young, C., King, F., Clague, M., Caldwell, M., Boruah, A., Zucker, J., Thakur, K. T. Tags: Autoimmune diseases, Post-infectious, Inclusion, Diversity, Equity, Anti-racism, and Social Justice (IDEAS), COVID-19 Research Article Source Type: research

Infection, vaccination, and childhood arterial ischemic stroke
A stroke occurs when a blood vessel to the brain is either blocked or ruptured. When blood to part of the brain is blocked, it causes what is called an ischemic stroke. Stroke is much more common in adults and the elderly. This is because fats and cholesterol can build up and block blood vessels as we age. Stroke is much less common in children. Stroke occurs in 11 per 100,000 children under the age of 18 every year.1 Still, it is one of the top 10 causes of death for children.2 We don't routinely expect children to have the major risk factors for atherosclerosis, such as high blood pressure, diabetes, high cholesterol, an...
Source: Neurology - October 26, 2015 Category: Neurology Authors: Woo, D. Tags: Childhood stroke, All Infections, All Cerebrovascular disease/Stroke, All Pediatric, Pediatric stroke; see Cerebrovascular Disease/ Childhood stroke PATIENT PAGES Source Type: research

A call for new attitudes on infection, vaccination, and childhood stroke
Population-based estimates of the incidence of childhood stroke range from 2.6 to 13 cases per 100,000 children per year. Unlike in adults, conventional stroke risk factors such as arterial hypertension, diabetes, and cigarette smoking make little contribution to the etiology of stroke in children. Developmental, genetic, and environmental factors are major contributors to ischemic stroke in children.
Source: Neurology - October 26, 2015 Category: Neurology Authors: Biller, J., Heyer, G. L. Tags: Childhood stroke, All Infections, Pediatric stroke; see Cerebrovascular Disease/ Childhood stroke, Case control studies EDITORIALS Source Type: research