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A case with prolonged headache after COVID-19 vaccination and later developed Bell's palsy
CONCLUSION: Reactivation of latent herpes virus has been suggested as one of the possible mechanisms underlying the phenomenon, but the causal pathophysiology related to the symptom needs further validation. Moreover, in the event of facial palsy post-vaccination, alternative diagnoses such as Guillain-Barre syndrome (GBS), Ramsey-Hunt syndrome, Lyme disease, trauma, central nervous system infection (CNS) infection, or stroke should also be considered.PMID:37198509
Source: Acta Neurologica Taiwanica - May 17, 2023 Category: Neurology Authors: Yi-Yang Hsiao Ling-Jun Liu Yo-Lin Lin Source Type: research

New VOYAGER PAD Analysis Confirms Consistent Benefit of XARELTO ® (rivaroxaban) Plus Aspirin Following Lower Extremity Revascularization (LER)
TITUSVILLE, NJ, March 5, 2023 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced data from a new prespecified analysis from the Phase 3 VOYAGER PAD clinical trial reinforcing the benefits of the XARELTO® (rivaroxaban) vascular dose (2.5 mg twice daily plus aspirin 100 mg once daily) over standard of care (aspirin alone), demonstrating consistent benefit at 30 days, 90 days and up to three years following LER in patients with PAD. Lower extremity revascularization, also called peripheral revascularization, is a procedure that restores blood flow in blocked arteries or veins. This analysis of ...
Source: Johnson and Johnson - March 5, 2023 Category: Pharmaceuticals Tags: Latest News Source Type: news

Investigation of Neurological Complications after COVID-19 Vaccination: Report of the Clinical Scenarios and Review of the Literature
Vaccines (Basel). 2023 Feb 13;11(2):425. doi: 10.3390/vaccines11020425.ABSTRACTCoronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), broke out in 2019 and became a pandemic in 2020. Since then, vaccines have been approved to prevent severe illness. However, vaccines are associated with the risk of neurological complications ranging from mild to severe. Severe complications such as vaccine-induced immune thrombotic thrombocytopenia (VITT) associated with acute ischaemic stroke have been reported as rare complications post-COVID-19 vaccination. During the pandemic era, V...
Source: Herpes - February 28, 2023 Category: Infectious Diseases Authors: Wei-Ping Chen Ming-Hua Chen Shih-Ta Shang Yung-Hsi Kao Kuo-An Wu Wen-Fang Chiang Jenq-Shyong Chan Hann-Yeh Shyu Po-Jen Hsiao Source Type: research

Comment on vaccine associated benign headache and cutaneous hemorrhage after ChAdOx1 nCoV-19 vaccine
Dear Editor, we would like to share ideas on the publication “Vaccine associated benign headache and cutaneous hemorrhage after ChAdOx1 nCoV-19 vaccine: A cohort study1.” If these symptoms are a minor form of VITT, with a possibility for worsening, such as in the case of a second vaccination dose, or a new entity of vaccine consequences, Schultz et al. ex plored this1. The combination of headaches and subcutaneous hemorrhage, according to Schultz et al., did not indicate VITT, and no other distinct coagulation problem or cerebral pathology was discovered.
Source: Journal of Stroke and Cerebrovascular Diseases - January 23, 2023 Category: Neurology Authors: Rujittika Mungmunpuntipantip, Viroj Wiwanitkit Tags: Letter to the Editor Source Type: research

Response to Letter to the Editor
We thank the authors for their interest in our article and the thoughtful comments. As they correctly point out, the association between the first vaccination with ChAdOx1 nCov -19 vaccine and the described symptoms in our article does not prove any causality. However, cutaneous hemorrhages and headaches were frequently reported side effects after vaccination with ChAdOx1 nCov-19 in the Norwegian corona study cohort in young and previously healthy subjects. In lack of previous experience, there was a fear that these symptoms may have represented a mild form of VITT.
Source: Journal of Stroke and Cerebrovascular Diseases - January 20, 2023 Category: Neurology Tags: Letter to the Editor Source Type: research

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