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Acute ischemic stroke in children & #8211; should we thrombolyze ?
KP Vinayan, Vivek Nambiar, Vaishakh AnandAnnals of Indian Academy of Neurology 2022 25(1):21-25 Ischemic stroke is a major cause of acute neurological symptoms in children with significant long-term neurological sequelae. Unlike in the adult population, the clinical presentation of strokes in children may not be stereotyped. Hence, many other differential diagnostic possibilities might have to be considered in the emergency setting. Due to this heterogeneous presentation and the resultant clinical dilemma in the early detection, acute thrombolysis even now remains as a very rarely tried therapeutic option in children. Man...
Source: Annals of Indian Academy of Neurology - February 22, 2022 Category: Neurology Authors: KP Vinayan Vivek Nambiar Vaishakh Anand Source Type: research

28675 A case of systemic amyloidosis diagnosed by dermatologic consult
A 49-year-old male with PMH of hypertension and diabetes was admitted to the neurology ICU following thrombolytic therapy for left MCA occlusive thrombus. Dermatology was consulted for desquamation of the lower lip, lateral tongue, and bruising of the eyelid and cheeks. Patient originally presented to outside hospital with bilateral lower extremity swelling and shortness of breath. BNP and troponins were elevated, and ACS protocol was initiated. He had stroke-like symptoms while at the outside facility and CT showed MCA occlusive thrombus.
Source: Journal of the American Academy of Dermatology - August 8, 2021 Category: Dermatology Authors: Alison Huber, Dr. Emily Smith Source Type: research

Factors influencing nonadministration of thrombolytic therapy in early arrival strokes in a university hospital in Hyderabad, India
Conclusion: One-fourth of early ischemic stroke patients in our study were not thrombolyzed even though they arrived within the window period. The majority of the reasons for nonadministration of thrombolysis were potentially preventable, such as nonaffordability, intrahospital delay, and nonavailability of newer endovascular interventions.
Source: Annals of Indian Academy of Neurology - July 24, 2016 Category: Neurology Authors: Lalitha Pidaparthi Anitha Kotha Venkat Reddy Aleti Abhijeet Kumar Kohat Mridula R Kandadai Suryaprabha Turaga Jabeen A Shaik Suvarna Alladi Meena A Kanikannan Borgohain Rupam Subhash Kaul Source Type: research

Fifty years of stroke researches in India
Tapas Kumar Banerjee, Shyamal Kumar DasAnnals of Indian Academy of Neurology 2016 19(1):1-8Currently, the stroke incidence in India is much higher than Western industrialized countries. Large vessel intracranial atherosclerosis is the commonest cause of ischemic stroke in India. The common risk factors, that is, hypertension, diabetes, smoking, and dyslipidemia are quite prevalent and inadequately controlled; mainly because of poor public awareness and inadequate infrastructure. Only a small number of ischemic stroke cases are able to have the benefit of thrombolytic therapy. Benefits from stem cell therapy in established ...
Source: Annals of Indian Academy of Neurology - February 2, 2016 Category: Neurology Authors: Tapas Kumar BanerjeeShyamal Kumar Das Source Type: research

Ways To Improve Door-to-Needle Times in Stroke Treatment
WASHINGTON, DC — A streamlined emergency care service and a low-cost, tablet-based mobile telestroke system are two examples of shortening the time it takes for acute ischemic stroke patients to receive thrombolytic therapy that were presented at the annual meeting of the American Academy of Neurology.
Source: Caring for the Ages - August 1, 2015 Category: Health Management Authors: Elizabeth Mechcatie Source Type: news

HAT Score Outperforms 7 Other Hemorrhagic Transformation Scores in Ischemic Stroke Patients Treated with Thrombolysis (P3.109)
Conclusions: HAT score yielded the highest odds ratio among the 4 scores that accurately predicted sICH in our independent dataset. HAT score also had low computational complexity compared to other scores. Our results demonstrate the potential utility of the HAT score as a predictor of adverse clinical outcome for acute ischemic stroke patients undergoing IV thrombolytic therapy.Disclosure: Dr. Asuzu has nothing to disclose. Dr. Nystrom has nothing to disclose. Dr. Halliday has nothing to disclose. Dr. Wira has nothing to disclose. Dr. Greer has nothing to disclose. Dr. Schindler has nothing to disclose. Dr. Sheth has rece...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Asuzu, D., Nystrom, K., Halliday, J., Wira, C., Greer, D., Schindler, J., Sheth, K. Tags: Cerebrovascular Disease and Interventional Neurology: t-PA Source Type: research