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High-intensity focused ultrasound: past, present, and future in neurosurgery.
Abstract Since Lynn and colleagues first described the use of focused ultrasound (FUS) waves for intracranial ablation in 1942, many strides have been made toward the treatment of several brain pathologies using this novel technology. In the modern era of minimal invasiveness, high-intensity focused ultrasound (HIFU) promises therapeutic utility for multiple neurosurgical applications, including treatment of tumors, stroke, epilepsy, and functional disorders. Although the use of HIFU as a potential therapeutic modality in the brain has been under study for several decades, relatively few neuroscientists, neurologi...
Source: Neurosurgical Focus - February 1, 2018 Category: Neurosurgery Authors: Quadri SA, Waqas M, Khan I, Khan MA, Suriya SS, Farooqui M, Fiani B Tags: Neurosurg Focus Source Type: research

Magnetic resonance-guided, high-intensity focused ultrasound sonolysis: potential applications for stroke.
Abstract Stroke is one of the leading causes of death worldwide and a significant source of long-term morbidity. Unfortunately, a substantial number of stroke patients either are ineligible or do not significantly benefit from contemporary medical and interventional therapies. To address this void, investigators recently made technological advances to render transcranial MR-guided, high-intensity focused ultrasound (MRg-HIFU) sonolysis a potential therapeutic option for both acute ischemic stroke (AIS)-as an alternative for patients with emergent large-vessel occlusion (ELVO) who are ineligible for endovascular me...
Source: Neurosurgical Focus - February 1, 2018 Category: Neurosurgery Authors: Ilyas A, Chen CJ, Ding D, Romeo A, Buell TJ, Wang TR, Kalani MYS, Park MS Tags: Neurosurg Focus Source Type: research