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Is Total Arch Replacement Associated With Worse Outcomes During Repair of Acute Type A Aortic Dissection?
CONCLUSIONS: Acute type A aortic dissection remains a challenge associated with significant mortality and morbidity. When compared with a less aggressive resection, total arch replacement performed in an individualized fashion can be associated with acceptable early and late outcomes for ATAAD and was not associated with worse outcomes. PMID: 26271582 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - August 11, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Rice RD, Sandhu HK, Leake SS, Afifi RO, Azizzadeh A, Charlton-Ouw KM, Nguyen TC, Miller CC, Safi HJ, Estrera AL Tags: Ann Thorac Surg Source Type: research

Moderate Versus Deep Hypothermia With Unilateral Selective Antegrade Cerebral Perfusion for Acute Type A Dissection.
CONCLUSIONS: Moderate HCA with uSACP is an effective circulation management strategy that provides excellent cerebral and visceral protection during emergent ATAAD repair. In the setting of antegrade cerebral perfusion, deep hypothermia does not provide any additional benefit. PMID: 26233273 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - July 30, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Leshnower BG, Thourani VH, Halkos ME, Sarin EL, Keeling WB, Lamias MJ, Guyton RA, Chen EP Tags: Ann Thorac Surg Source Type: research

Outcomes of Open Repair for Chronic Descending Thoracic Aortic Dissection
Conclusions Open repairs of chronic descending thoracic aortic aneurysm dissections can be performed with respectable morbidity and mortality. Neurologic deficit remains low with the use of adjuncts, and early deaths are directly related to preoperative renal status. Reintervention on the involved aortic segment is low. These results allow comparisons with endovascular repair for chronic aortic dissection.
Source: The Annals of Thoracic Surgery - January 23, 2015 Category: Cardiovascular & Thoracic Surgery Source Type: research

Outcomes of Open Repair for Chronic Descending Thoracic Aortic Dissection.
CONCLUSIONS: Open repairs of chronic descending thoracic aortic aneurysm dissections can be performed with respectable morbidity and mortality. Neurologic deficit remains low with the use of adjuncts, and early deaths are directly related to preoperative renal status. Reintervention on the involved aortic segment is low. These results allow comparisons with endovascular repair for chronic aortic dissection. PMID: 25617229 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - January 21, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Estrera AL, Jan A, Sandhu H, Shalhub S, Medina-Castro M, Nguyen TC, Azizzadeh A, Charlton-Ouw K, Miller CC, Safi HJ Tags: Ann Thorac Surg Source Type: research

276 * deep hypothermic circulatory arrest for concomitant procedures in patients undergoing heart transplantation
Conclusion: Concomitant procedures requiring deep hypothermic circulatory arrest during heart transplantation can be safely performed without compromising patient survival and donor allograft function over mid-term follow-up.
Source: Interactive CardioVascular and Thoracic Surgery - September 23, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Vallabhajosyula, P., Menon, R., Gottret, J., Komlo, C., Atluri, P., Acker, M. Tags: Heart transplantation Source Type: research

126 * extra-anatomic revascularisation for distal occlusion of the left or right common carotid artery in acute type a aortic dissection with cerebral malperfusion
Conclusion: Extra-anatomic bypass for distal LCCA or RCCA occlusion presents a valuable bail-out technique to restore cerebral perfusion during AADA repair, potentially reducing the increased incidence of neurological complications in patients with cerebral malperfusion.
Source: Interactive CardioVascular and Thoracic Surgery - September 23, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Luehr, M., Etz, C. D., Lehmkuhl, L., Misfeld, M., Bakhtiary, F., Borger, M., Mohr, F. Tags: Complicated type A aortic dissection: Malperfusion and outcome Source Type: research

Cerebral Blood Flow in Patients With Peritoneal Dialysis by an Easy Z‐Score Imaging System for Brain Perfusion Single‐Photon Emission Tomography
In conclusion, all PD patients in the present study had decreased rCBF irrespective of MMSE scores.
Source: Therapeutic Apheresis and Dialysis - June 26, 2014 Category: Hematology Authors: Rei Isshiki, Shuzo Kobayashi, Masao Iwagami, Daimu Tsutumi, Yasuhiro Mochida, Kunihiro Ishioka, Machiko Oka, Kyoko Maesato, Hidekazu Moriya, Takayasu Ohtake, Sumi Hidaka Tags: Original Article Source Type: research

Thoracic aortic aneurysms in octogenarians: the results of open surgical repair using hypothermic circulatory arrest with antegrade selective cerebral perfusion.
Conclusion: The early and late outcomes after thoracic aortic surgery at our hospital using HCA with ASCP in octogenarians are acceptable. The operations are performed with an acceptable operative risk, even under emergency situations, including acute aortic dissection. PMID: 24614390 [PubMed - in process]
Source: Journal of Nippon Medical School - March 15, 2014 Category: Universities & Medical Training Authors: Bessho R, Ishii Y, Nishina D, Kawase Y Tags: J Nippon Med Sch Source Type: research

The acute management of haemorrhage, surgery and overdose in patients receiving dabigatran
Dabigatran is an oral direct thrombin inhibitor (DTI) licensed for stroke prevention in atrial fibrillation and likely to be soon approved in Europe for treatment of venous thrombosis. Predictable pharmacokinetics and a reduced risk of intracranial haemorrhage do not negate the potential risk of haemorrhage. Unlike warfarin, there is no reversal agent and measurement of the anticoagulant effect is not ‘routine’. The prothrombin time/international normalised ratio response to dabigatran is inconsistent and should not be measured when assessing a patient who is bleeding or needs emergency surgery. The activated p...
Source: Emergency Medicine Journal - January 15, 2014 Category: Emergency Medicine Authors: Alikhan, R., Rayment, R., Keeling, D., Baglin, T., Benson, G., Green, L., Marshall, S., Patel, R., Pavord, S., Rose, P., Tait, C. Tags: Poisoning/Injestion, Open access, Drugs: cardiovascular system, Stroke, Poisoning Review Source Type: research

Hypertension - human studies
Conclusions:Higher predialysis SBP variability is associated with stroke on HD populations suggesting a potential role for cerebral perfusion instability. We confirm known associations between age, diabetes, pre-existent cerebrovascular disease and hypertension. In contrast to studies in non-dialysis patients we do not find an association between EPO dose and stroke. Interventional trials of blood pressure management on stroke are recommended.
Source: Nephrology Dialysis Transplantation - May 10, 2013 Category: Urology & Nephrology Authors: Power, A., Duncan, N., Pusey, C., Usvyat, L., Marcelli, D., Marelli, C., Kotanko, P., MONDO Consortium, Li, Z., Wang, J., Yuan, X., Wang, J., Wang, L., Ozkayar, N., Altun, B., Yildirim, T., Yilmaz, R., Dede, F., Hayran, M., Arici, M., Aki, T., Erdem, Y., Tags: Abstracts Source Type: research

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