Elusive Therapeutic Effect of PCSK9 Inhibitors on Lipoprotein(a) Levels
Therapeutic Apheresis and Dialysis, EarlyView. (Source: Therapeutic Apheresis and Dialysis)
Source: Therapeutic Apheresis and Dialysis - November 26, 2018 Category: Hematology Authors: Francesco Sbrana, Federico Bigazzi, Beatrice Dal Pino, Maddalena Toma, Andrea Ripoli, Tiziana Sampietro Tags: Letter to the Editor Source Type: research

Do pre ‐haemodialysis estimates of extracellular volume excess using bioimpedance and N terminal brain natriuretic peptide correlate with cardiac chamber size measured by magnetic resonance imaging ?
ConclusionPre ‐HD NT‐proBNP was associated with left sided cardiac chamber sizes, but not with right sided chamber sizes, whereas ECW/height was associated with right sided cardiac chamber sizes. As right sided cardiac chamber size is more responsive to and reflective of changes in intravascular volume than t he left atrium and ventricle, then bioimpedance measured ECW is potentially more reliable in estimating plasma volume expansion.This article is protected by copyright. All rights reserved. (Source: Therapeutic Apheresis and Dialysis)
Source: Therapeutic Apheresis and Dialysis - November 23, 2018 Category: Hematology Authors: Suree Yoowannakul, Tushar Kotecha, Marianna Fontana, Andrew Davenport Tags: Original Article Source Type: research

Pulmonary hypertension predicts adverse outcomes in renal patients: a systematic review and Meta ‐Analysis
ABSTRACTIn the general population and in heart disease, pulmonary hypertension (PH) is a strong and independent risk factor for mortality and adverse cardiovascular outcomes. We performed a systematic review and meta ‐analysis of longitudinal cohort studies of individuals with chronic kidney disease (CKD) of any‐stage (also including end‐stage kidney disease –ESKD‐ and kidney transplantation) stratified according to presence/absence of PH.18 eligible studies (10740 participants) were retrieved. PH had an overall pooled prevalence (PP) of 33% (95% CI 28 ‐42) and portended a higher risk of all‐cause mortality (...
Source: Therapeutic Apheresis and Dialysis - November 22, 2018 Category: Hematology Authors: Davide Bolignano, Anna Pisano, Giuseppe Coppolino, Giovanni Luigi Tripepi, Graziella D ’Arrigo Tags: Review Source Type: research

Relationship between Patterns in Antihypertensive Drugs Medication and Mortality in Incident Dialysis Patients: A Multicenter Prospective Cohort Study
We examined antihypertensive drug prescription patterns at baseline, as well as the association between use of antihypertensive drugs and mortality after dialysis initiation. Among all participants, 1,440 were taking at least one antihypertensive drug. The rate of calcium channel blocker (CCB) use was highest, accounting for 74.3%. CCB use was significantly associated with lower all ‐cause and cardiovascular‐related mortality [hazard ratio (HR): 0.62 and 0.57, 95% confidence interval (CI): 0.46–0.85 and (0.35–0.91), respectively]. Compared with no use of either drug, combination therapy with a renin angiotensin sys...
Source: Therapeutic Apheresis and Dialysis - November 22, 2018 Category: Hematology Authors: Maya Fujii, Daijo Inaguma, Shigehisa Koide, Eri Ito, Kazuo Takahashi, Hiroki Hayashi, Naotake Tsuboi, Midori Hasegawa, Yukio Yuzawa Tags: Original Article Source Type: research

Is Plasma Exchange Efficacious in Shiga Toxin ‐Associated Hemolytic Uremic Syndrome? A Narrative Review of Current Evidence
AbstractShiga toxin ‐associated hemolytic uremic syndrome (STEC‐HUS) is associated with significant mortality and morbidity. Case fatalities are often associated with severe neurological involvement in children and advanced age in adults but specific treatment is currently unavailable. Plasma exchange (PE) could th eoretically enable removal of Shiga toxins, pro‐inflammatory cytokines, and prothrombotic factors and has been used in deteriorating patients with STEC‐HUS but the efficacy remains uncertain. In order to assess efficacy of PE in STEC‐HUS, a literature review was performed. PubMed, Web of Scien ce, Emba...
Source: Therapeutic Apheresis and Dialysis - November 19, 2018 Category: Hematology Authors: Werner Keenswijk, Ann Raes, Marieke De Clerck, Johan Vande Walle Tags: Review Source Type: research

Which Type of Temporary Hemodialysis Catheter to Be Used for the Right Internal Jugular Vein? Prospective Observational Study of Straight vs Precurved Caths
ConclusionsThrombosis rates of the RIJV was higher with straight versus precurved THCs, both during catheter dwell ‐time and after catheter removal. Catheter dysfunction was not noted in any group and the rate of CRBI was extremely low. (Source: Therapeutic Apheresis and Dialysis)
Source: Therapeutic Apheresis and Dialysis - November 16, 2018 Category: Hematology Authors: Tuncay Sahutoglu, Osman Erinc, Fevzi Necati Avsar, Meral Beyaz, Aziz Batu, Kadri Atay, Erman Ozdemir, Aysegul Erinc, Elif Sahutoglu Tags: Original Article Source Type: research

Heart Valve Disease Predict Mortality in Hemodiaylsis Patients: A Single Center Experience
DiscussionAge, coronary artery disease and especially pathology in more than one heart valve are risk factors for mortality. Heart valve problems might developed due to malnutrition and inflammation caused by the chronic renal failure. (Source: Therapeutic Apheresis and Dialysis)
Source: Therapeutic Apheresis and Dialysis - November 13, 2018 Category: Hematology Authors: Ruya Ozelsancak, Nihan Tekkar ısmaz, Dilek Torun, Hasan Micozkadioglu Tags: Original Article Source Type: research

Effect of hemodialysis on the red blood cell life span in patients with end ‐stage kidney disease
In conclusion, dialysis using a polysulfone membrane did not appear to disrupt red blood cells or reduce their lifespan in patients with end ‐stage kidney disease. (Source: Therapeutic Apheresis and Dialysis)
Source: Therapeutic Apheresis and Dialysis - November 13, 2018 Category: Hematology Authors: Junfeng Luo, Jiuhong Li, Junjie Nie, Pingping Li, Houde Zhang, Yongjian Ma Tags: Original Article Source Type: research

Secondary hyperparathyroidism: Pathogenesis and latest treatment
AbstractThe classic pathogenesis of secondary hyperparathyroidism (SHPT) began with the trade ‐off hypothesis based on parathyroid hormone (PTH) hypersecretion brought about by renal failure resulting from a physiological response to correct metabolic disorder of calcium, phosphorus, and vitamin D. In dialysis patients with failed renal function, physiological mineral balance control by PT H through the kidney fails and hyperparathyroidism progresses. In this process, many significant genetic findings have been established. Abnormalities of Ca‐sensing receptor and vitamin D receptor are associated with the pathogenesis...
Source: Therapeutic Apheresis and Dialysis - November 8, 2018 Category: Hematology Authors: Masahide Mizobuchi, Hiroaki Ogata, Fumihiko Koiwa Tags: Review Source Type: research

Hepcidin/Ferritin Ratios Differ Among Non ‐dialyzed Chronic Kidney Disease Patients, and Patients on Hemodialysis and Peritoneal Dialysis
AbstractThe serum levels of hepcidin generally increase in patients with chronic kidney disease (CKD) due to inflammation or a decline in the glomerular filtration rate. However, the differences in the ferrokinetics among dialysis modalities are unclear. We investigated the relationship between serum levels of hepcidin and ferritin among non ‐dialyzed CKD (ND), hemodialysis (HD), and peritoneal dialysis (PD) patients. We recruited 285 CKD patients (117 ND, 80 HD, and 88 PD patients) and measured the serum levels of hepcidin‐25, ferritin, hemoglobin, iron, transferrin saturation (TSAT), albumin, and high sensitivity C...
Source: Therapeutic Apheresis and Dialysis - November 8, 2018 Category: Hematology Authors: Takahito Niikura, Yukio Maruyama, Satomi Nakashima, Nanae Matsuo, Yudo Tanno, Ichiro Ohkido, Keitaro Yokoyama, Hiroyasu Yamamoto, Takashi Yokoo Tags: Original Article Source Type: research

Impact of Dialysate Sodium Concentration Lowering on Home Blood Pressure Variability in Hemodialysis Patients
Therapeutic Apheresis and Dialysis,Volume 0, Issue ja, -Not available-. (Source: Therapeutic Apheresis and Dialysis)
Source: Therapeutic Apheresis and Dialysis - November 1, 2018 Category: Hematology Authors: Ziye Chen, Fang Sun, Yang Shen, Lijie Ma, Jing Liu, Yilun Zhou Source Type: research

Self ‐care Behavior of Hemodialysis Patients with Arteriovenous Fistula in China: A Multicenter, Cross‐sectional Study
Therapeutic Apheresis and Dialysis,Volume 0, Issue ja, -Not available-. (Source: Therapeutic Apheresis and Dialysis)
Source: Therapeutic Apheresis and Dialysis - October 31, 2018 Category: Hematology Authors: Miao ‐miao Yang, Hui‐hua Zhao, Xiao‐qiang Ding, Guo‐hong Zhu, Zhen‐hua Yang, Lin Ding, Xiong‐hao Yang, Yuan Zhao, Lei Chen, Ren‐mei Yang, Jian Fang, Clemente Neves Sousa Source Type: research

Atypical Hemolytic ‐Uremic Syndrome: An Update on Pathophysiology, Diagnosis, and Treatment
Therapeutic Apheresis and Dialysis, EarlyView. (Source: Therapeutic Apheresis and Dialysis)
Source: Therapeutic Apheresis and Dialysis - October 29, 2018 Category: Hematology Authors: Rupesh Raina, Vinod Krishnappa, Taryn Blaha, Taylor Kann, William Hein, Linda Burke, Arvind Bagga Source Type: research

Better Oral Hygiene Habits Are Associated With a Lower Incidence of Peritoneal Dialysis ‐Related Peritonitis
Therapeutic Apheresis and Dialysis, EarlyView. (Source: Therapeutic Apheresis and Dialysis)
Source: Therapeutic Apheresis and Dialysis - October 24, 2018 Category: Hematology Authors: Hideaki Oka, Shunsuke Yamada, Taro Kamimura, Seishi Aihara, Masahide Hyodo, Nagaaki Terakado, Atsumi Harada, Toshiaki Nakano, Kazuhiko Tsuruya, Takanari Kitazono Source Type: research

Influence of Physical Exercise on the Dialytic Adequacy Parameters of Patients on Hemodialysis
Therapeutic Apheresis and Dialysis, EarlyView. (Source: Therapeutic Apheresis and Dialysis)
Source: Therapeutic Apheresis and Dialysis - October 19, 2018 Category: Hematology Authors: Alicia Garc ía Testal, Rafael García Maset, David Hervás Marín, Borja Pérez‐Domínguez, Pilar Royo Maicas, Inmaculada Soledad Rico Salvador, Erika Meléndez‐Oliva, Javier Molina Aracil, MªJosé Murgui Chiva, Olga Del pozo Blanco, Pau O Source Type: research