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Specialty: Veterinary Research
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Total 145 results found since Jan 2013.
Study seeks to understand how dogs might help spinal patients' rehabilitation
A COLLABORATION between the NHS and a canine charity is to investigate how dogs may aid recovery in people with spinal injuries. Patients at the National Spinal Injuries Centre (NSIC) at Stoke Mandeville Hospital will take part in a pilot trial of Animal Assisted Intervention (AAI) with a trained therapy dog from the charity Dogs for Good. AAI is a well-established practice in many parts of the world, but is less advanced in the UK. Charlotte Simcock, a patient at the NSIC, suffered a spinal stroke in 2016 that left her with limited movement from the chest down. Her wish is to improve movement in her arms so she can feed h...
Source: Veterinary Record - April 27, 2017 Category: Veterinary Research Tags: News section Source Type: research
Neurological manifestations in dogs naturally infected by Leishmania infantum: descriptions of 10 cases and a review of the literature
This study confirms that both central and peripheral nervous systems can be affected by leishmaniasis and provides an overview on the possible etiopathogenetic mechanisms. In addition, clinical and diagnostic findings, therapy and follow‐up of affected dogs are described.
Source: The Journal of Small Animal Practice - March 6, 2017 Category: Veterinary Research Authors: A. P. Giannuzzi, M. Ricciardi, A. De Simone, F. Gernone Tags: REVIEW Source Type: research
Effects of maintaining different exercise intensities during detraining on aerobic capacity in Thoroughbreds.
CONCLUSIONS AND CLINICAL RELEVANCE Horses following the cantering detraining protocol maintained higher values of several performance variables compared with horses following the walking or stall rest protocols. These results suggested that it may be possible to identify a minimal threshold exercise intensity or protocol during detraining that would promote maintenance of important performance-related variables and minimize reductions in oxygen-transport capacity in horses.
PMID: 28140647 [PubMed - in process]
Source: American Journal of Veterinary Research - January 31, 2017 Category: Veterinary Research Authors: Mukai K, Hiraga A, Takahashi T, Matsui A, Ohmura H, Aida H, Jones JH Tags: Am J Vet Res Source Type: research
Spontaneous ischaemic stroke lesions in a dog brain: neuropathological characterisation and comparison to human ischaemic stroke
Dogs develop spontaneous ischaemic stroke with a clinical picture closely resembling human ischaemic stroke patients. Animal stroke models have been developed, but it has proved difficult to translate results ...
Source: Acta Veterinaria Scandinavica - January 13, 2017 Category: Veterinary Research Authors: Barbara Blicher Thomsen, Hanne Gredal, Martin Wirenfeldt, Bjarne Winther Kristensen, Bettina Hjelm Clausen, Anders Elm Larsen, Bente Finsen, Mette Berendt and Kate Lykke Lambertsen Source Type: research
Cardiac magnetic resonance imaging of patent ductus arteriosus in three dogs
Patent ductus arteriosus (PDA) is the most common congenital cardiovascular disorder in dogs and requires an accurate diagnosis for an appropriate treatment. Cardiac MRI (cMRI) has been reported as a method for characterization of canine thoracic vasculature. However, to the authors’ knowledge, no published studies describe evaluation of canine PDA through cMRI. Three dogs were selected for this exploratory study. Electrocardiogram gating and breath‐hold techniques were performed using a 3T MR scanner. Both black blood imaging and bright blood cine acquisitions were performed. Quantification of stroke volume (SV) and s...
Source: Veterinary Radiology and Ultrasound - November 19, 2016 Category: Veterinary Research Authors: Youngjae Lee, Jaihyun Jung, Junyong Park, Jiyoon Jeong, Seokho Jeon, Sunyoung Park, Jinhwa Chang, Ji ‐Houn Kang, Chulhyun Lee, Dongwoo Chang Tags: Original Investigation Source Type: research
Left atrial volume and function in dogs with naturally occurring myxomatous mitral valve disease
Conclusion Dogs with MMVD appear to have larger LA volumes with poorer LA function. Deteriorating LA function, characterized by a decreasing reservoir and active contractile function, was evident in dogs with MMVD with increasing disease severity.
Source: Journal of Veterinary Cardiology - November 5, 2016 Category: Veterinary Research Source Type: research
Application of an innovative technique for unilateral ovariectomy in dairy cows
This report describes an innovative unilateral ovariectomy technique for the surgical treatment of follicular cysts in dairy cows. Five cows, with a diagnosis of follicular cysts, were submitted to unilateral ovariectomy via a paralumbar fossa approach, in standing position. The linear cutter proved useful for clamping the ovary, stapling the vessels and cutting in one stroke, thus reducing surgery times. After unilateral ovariectomy, all cows underwent heat 7–30 days after surgery, and three cows became pregnant. All cows showed increased milk production. The results of this case report showed that flank ovarie...
Source: Veterinary Record - November 2, 2016 Category: Veterinary Research Authors: Rizzo, A., Piccinno, M., Lacitignola, L., D'Onghia, G., D'Onghia, G. F., Sciorsci, R. L. Tags: Research Source Type: research
Assessment of left ventricular volume and function in healthy dogs by use of one-, two-, and three-dimensional echocardiography versus multidetector computed tomography.
CONCLUSIONS AND CLINICAL RELEVANCE Values for EDV and ESV obtained by use of 3-D echocardiography, including RTBPE and RT3DE, had the highest correlation with slight underestimation, compared with values obtained by use of MDCT. This was similar to results for 3-D echocardiography in human medicine.
PMID: 27805446 [PubMed - in process]
Source: American Journal of Veterinary Research - October 31, 2016 Category: Veterinary Research Authors: Scollan KF, Stieger-Vanegas SM, Sisson DD Tags: Am J Vet Res Source Type: research
Cardiovascular effects of dexmedetomidine, with or without MK ‐467, following intravenous administration in cats
Conclusion and clinical relevanceFollowing IV co‐administration, MK‐467 effectively attenuated dexmedetomidine‐induced cardiovascular effects in cats. The drug combination resulted in transient reduction in arterial blood pressure, without causing hypotension.
Source: Veterinary Anaesthesia and Analgesia - July 4, 2016 Category: Veterinary Research Authors: Bruno H Pypendop, Juhana Honkavaara, Jan E Ilkiw Tags: Research Paper Source Type: research
Effects of preoperative carprofen on cardio-respiratory, hormonal and metabolic stress response in calves during umbilical surgery under isoflurane inhalation anaesthesia
In conclusion, the anaesthetic protocol used in this study induced reliable analgesia in both groups. The lower serum cortisol levels and SVR may indicate a reduced surgical stress response in calves undergoing umbilical surgery under ISO anaesthesia after administering carprofen preoperatively.
Source: The Veterinary Journal - July 3, 2016 Category: Veterinary Research Source Type: research
Cardiovascular effects of dexmedetomidine, with or without MK‐467, following intravenous administration in cats
Conclusion and clinical relevanceFollowing IV co‐administration, MK‐467 effectively attenuated dexmedetomidine‐induced cardiovascular effects in cats. The drug combination resulted in transient reduction in arterial blood pressure, without causing hypotension.
Source: Veterinary Anaesthesia and Analgesia - June 30, 2016 Category: Veterinary Research Authors: Bruno H Pypendop, Juhana Honkavaara, Jan E Ilkiw Tags: Research Paper Source Type: research
Neurological signs in 23 dogs with suspected rostral cerebellar ischaemic stroke
In dogs with ischaemic stroke, a very common site of infarction is the cerebellum. The aim of this study was to characterise neurological signs in relation to infarct topography in dogs with suspected cerebell...
Source: Acta Veterinaria Scandinavica - June 7, 2016 Category: Veterinary Research Authors: Barbara Thomsen, Laurent Garosi, Geoff Skerritt, Clare Rusbridge, Tim Sparrow, Mette Berendt and Hanne Gredal Source Type: research
Electrical velocimetry for noninvasive cardiac output and stroke volume variation measurements in dogs undergoing cardiovascular surgery
Conclusions and clinical relevanceIn dogs undergoing cardiovascular surgery, EV provided accurate CO measurements compared with CIPAC, although its trending ability was poor. Further, SVV by EV, but not CVP, reliably predicted fluid responsiveness during mechanical ventilation in dogs.
Source: Veterinary Anaesthesia and Analgesia - April 30, 2016 Category: Veterinary Research Authors: Kazumasu Sasaki, Tatsushi Mutoh, Tomoko Mutoh, Ryuta Kawashima, Hirokazu Tsubone Tags: Research Paper Source Type: research
Changes in pulse pressure variation and plethysmographic variability index caused by hypotension-inducing hemorrhage followed by volume replacement in isoflurane-anesthetized dogs.
CONCLUSIONS AND CLINICAL RELEVANCE Results suggested that both PPV and PVI may be useful for identification of dogs that respond to VR with increases in SI and CI (ie, dogs in the preload-dependent limb of the Frank-Starling curve).
PMID: 26919599 [PubMed - in process]
Source: American Journal of Veterinary Research - February 28, 2016 Category: Veterinary Research Authors: Klein AV, Teixeira-Neto FJ, Garofalo NA, Lagos-Carvajal AP, Diniz MS, Becerra-Velásquez DR Tags: Am J Vet Res Source Type: research
Metronidazole pharmacokinetics during rapid growth in turkeys – relation to changes in haemodynamics and drug metabolism
Whereas interspecies variation in pharmacokinetics is a commonly investigated issue, variations in drug kinetics within a species are less documented. The aim of the study was to assess the influence of age‐related changes in haemodynamics on the pharmacokinetics of metronidazole (MTZ) and its hydroxy metabolite (MTZ‐OH) in turkeys. MTZ was administered intravenously and orally at a dose of 25 mg/kg. Plasma drug and metabolite concentrations were assessed by high‐performance liquid chromatography, and pharmacokinetic parameters were calculated by noncompartmental analysis. Haemodynamic parameters (heart rate, stroke...
Source: Journal of Veterinary Pharmacology and Therapeutics - January 27, 2016 Category: Veterinary Research Authors: M. Świtała, B. Poźniak, U. Pasławska, T. Grabowski, K. Motykiewicz‐Pers, K. Bobrek Tags: Scientific Paper Source Type: research
