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Specialty: Cardiology
Source: Atherosclerosis
Condition: Cardiomyopathy

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Total 38 results found since Jan 2013.

The multiple roles of lysophosphatidic acid in vascular disease and atherosclerosis
Curr Opin Lipidol. 2023 Jul 28. doi: 10.1097/MOL.0000000000000890. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: To explore the multiple roles that lysophosphatidic acid (LPA) plays in vascular disease and atherosclerosis.RECENT FINDINGS: A high-fat high-cholesterol diet decreases antimicrobial activity in the small intestine, which leads to increased levels of bacterial lipopolysaccharide in the mucus of the small intestine and in plasma that increase systemic inflammation, and enhance dyslipidemia and aortic atherosclerosis. Decreasing LPA production in enterocytes reduces the impact of the diet. LPA signaling inhibit...
Source: Atherosclerosis - July 27, 2023 Category: Cardiology Authors: Arnab Chattopadhyay Srinivasa T Reddy Alan M Fogelman Source Type: research

EXPRESS: Magnetic resonance imaging for diagnostic workup of Embolic Stroke of Undetermined Source: a systematic review
CONCLUSION: MRI techniques allow to identify additional cardiac and vascular embolic sources and may further decrease the prevalence of patients with the diagnosis of ESUS.PMID:37435743 | DOI:10.1177/17474930231189946
Source: Atherosclerosis - July 12, 2023 Category: Cardiology Authors: Natallia Khenkina Alberto Aimo Iacopo Fabiani Pier Giorgio Masci Dimitrios Sagris Steven E Williams George Mavraganis Hui-Sheng Chen Max Wintermark Patrik Michel George Ntaios George Georgiopoulos Source Type: research

Cardiovascular Effects of Cannabinoids
Cardiol Rev. 2023 Jun 29. doi: 10.1097/CRD.0000000000000566. Online ahead of print.ABSTRACTMarijuana is now one of the most widely used substances in the United States that has been rising in prevalence given increasing legalization and recreational and medical usage. Despite its widespread use, there have been increasing concerns regarding the cardiovascular safety of marijuana. Recent studies have found a link between marijuana use and the development of cardiovascular disease. Most notably, marijuana has been found to be associated with various cardiac complications, including atherosclerosis, myocardial infarction, str...
Source: Atherosclerosis - June 29, 2023 Category: Cardiology Authors: Andy Wang Subo Dey Sarah Subhan Jay Patel William H Frishman Wilbert S Aronow Source Type: research

A causal relationship between irritability and cardiovascular diseases: a Mendelian randomization study
CONCLUSION: Our findings support the first genetic evidence of the causality of genetically predicted irritability with the risk of developing into CVDs. Our results deliver a viewpoint that more early active interventions to manage an individual's anger and related unhealthy lifestyle habits are needed to prevent the occurrence of adverse cardiovascular events.PMID:37324625 | PMC:PMC10267866 | DOI:10.3389/fcvm.2023.1174329
Source: Atherosclerosis - June 16, 2023 Category: Cardiology Authors: Dihui Cai Yin Fu Yongfei Song Hui Lin Yanna Ba Jiangfang Lian Source Type: research

Substances of abuse and cardiovascular risk: cannabinoids
G Ital Cardiol (Rome). 2023 Jun;24(6):455-465. doi: 10.1714/4041.40205.ABSTRACTProgressive legalization for medical conditions or recreational use has led to an increased use of cannabis and synthetic cannabinoids over the past years. Most consumers are young and healthy, without cardiovascular risk factors; however, this population is expected to include older individuals. Thus, concerns have arisen about safety and short- and long-term potential adverse effects, with special emphasis on vulnerable groups. Studies show that cannabis might be linked with thrombosis, inflammation, and atherosclerosis, and many reports have ...
Source: Atherosclerosis - May 25, 2023 Category: Cardiology Authors: Maurizio G Abrignani Francesco Ciccirillo Pier Luigi Temporelli Arturo Cesaro Giulio Binaghi Alessandro Maloberti Chiara Cappelletto Fabrizio Oliva Carmine Riccio Pasquale Caldarola Domenico Gabrielli Furio Colivicchi Source Type: research

The epidemiology, mechanisms, diagnosis and treatment of cardiovascular disease in adult patients with HIV
This article discusses the complex interactions involving HIV infection, the novel and traditional risk factors for CVD, and the antiretroviral HIV therapies which can contribute to CVD in HIV-infected people. In addition, the treatment of HIV+ patients with acute myocardial infarction, stroke, and cardiomyopathy/heart failure are discussed. Current recommended ART and their major side effects are summarized in table format. All medical personnel must be aware of the increasing incidence of CVD on the morbidity and mortality in HIV infected patients and must be watchful for the presence of CVD in their patients with HIV.PM...
Source: Atherosclerosis - May 22, 2023 Category: Cardiology Authors: Robert J Henning John N Greene Source Type: research

Spleen tyrosine kinase (SYK) signals are implicated in cardio-cerebrovascular diseases
Heliyon. 2023 Apr 22;9(5):e15625. doi: 10.1016/j.heliyon.2023.e15625. eCollection 2023 May.ABSTRACTPost-translational modifications regulate numerous biochemical reactions and functions through covalent attachment to proteins. Phosphorylation, acetylation and ubiquitination account for over 90% of all reported post-translational modifications. As one of the tyrosine protein kinases, spleen tyrosine kinase (SYK) plays crucial roles in many pathophysiological processes and affects the pathogenesis and progression of various diseases. SYK is expressed in tissues outside the hematopoietic system, especially the heart, and is i...
Source: Atherosclerosis - May 14, 2023 Category: Cardiology Authors: Mohan Li Pengbo Wang Yuanming Zou Wenbin Wang Yuanhui Zhao Mengke Liu Jianlong Wu Ying Zhang Naijin Zhang Yingxian Sun Source Type: research

The Involvement of Kr üppel-like Factors in Cardiovascular Diseases
Life (Basel). 2023 Feb 2;13(2):420. doi: 10.3390/life13020420.ABSTRACTKrüppel-like factors (KLFs) are a set of DNA-binding proteins belonging to a family of zinc-finger transcription factors, which have been associated with many biological processes related to the activation or repression of genes, inducing cell growth, differentiation, and death, and the development and maintenance of tissues. In response to metabolic alterations caused by disease and stress, the heart will undergo cardiac remodeling, leading to cardiovascular diseases (CVDs). KLFs are among the transcriptional factors that take control of many physiolog...
Source: Atherosclerosis - February 25, 2023 Category: Cardiology Authors: Michelle G Santoyo-Suarez Jimena D Mares-Montemayor Gerardo R Padilla-Rivas Juan Luis Delgado-Gallegos Adriana G Quiroz-Reyes Jorge A Roacho-Perez Diego F Benitez-Chao Lourdes Garza-Oca ñas Gilberto Arevalo-Martinez Elsa N Garza-Trevi ño Jose Francisco Source Type: research

Patient characteristics and outcomes of acute myocardial infarction presenting without ischemic pain: Insights from the Atherosclerosis Risk in Communities Study
CONCLUSIONS: Future research should focus on differences in treatment delay across ischemic pain presentations rather than sex differences in acute coronary syndrome presentation.PMID:36713888 | PMC:PMC9879363 | DOI:10.1016/j.ahjo.2022.100239
Source: Atherosclerosis - January 30, 2023 Category: Cardiology Authors: Bailey M DeBarmore Jessica K Z ègre-Hemsey Anna M Kucharska-Newton Erin D Michos Wayne D Rosamond Source Type: research

Pharmacological and Molecular Insight on the Cardioprotective Role of Apigenin
Nutrients. 2023 Jan 12;15(2):385. doi: 10.3390/nu15020385.ABSTRACTApigenin is a naturally occurring dietary flavonoid found abundantly in fruits and vegetables. It possesses a wide range of biological properties that exert antioxidant, anti-inflammatory, anticancer, and antibacterial effects. These effects have been reported to be beneficial in the treatment of atherosclerosis, stroke, hypertension, ischemia/reperfusion-induced myocardial injury, and diabetic cardiomyopathy, and provide protection against drug-induced cardiotoxicity. These potential therapeutic effects advocate the exploration of the cardioprotective actio...
Source: Atherosclerosis - January 21, 2023 Category: Cardiology Authors: Shilu Deepa Thomas Niraj Kumar Jha Saurabh Kumar Jha Bassem Sadek Shreesh Ojha Source Type: research