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Cardiac Stroke Volume Index Is Associated With Early Neurological Improvement in Acute Ischemic Stroke Patients
Early neurological improvement as assessed with the NIH stroke scale (NIHSS) at 24 h has been associated with improved long-term functional outcomes following acute ischemic stroke (AIS). Cardiac dysfunction is often present in AIS, but its association with outcomes is incompletely defined. We performed a pilot study to evaluate the association between non-invasively measured cardiac parameters and 24-h neurological improvement in prospectively enrolled patients with suspected AIS who presented within 12 h of symptom-onset and had an initial systolic blood pressure>140 mm Hg. Patients receiving thrombolytic therapy or m...
Source: Frontiers in Physiology - November 18, 2021 Category: Physiology Source Type: research

Distinct plasma proteomic changes in male and female African American stroke patients.
CONCLUSION: Plasma proteins that differ in quantities between stroke patients and controls were readily detected using a simple proteomic approach. Sex-dependent changes and changes that have not been reported for African American stroke patients offer potentially novel biomarkers for stroke in this underserved population. PMID: 31149323 [PubMed]
Source: International Journal of Physiology, Pathophysiology and Pharmacology - June 4, 2019 Category: Physiology Tags: Int J Physiol Pathophysiol Pharmacol Source Type: research