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BMI Modifies the Association Between Depression Symptoms and Serum Copper Levels
Biol Trace Elem Res. 2022 Nov 27. doi: 10.1007/s12011-022-03505-y. Online ahead of print.ABSTRACTDepression is one of the most common mental disorders which dramatically threatens public health and wellness. Copper has been known to be involved in many biological processes that could help explaining the occurrence of depression. However, studies focusing on its effect have yielded mixed results. The present study aims to evaluate the association between serum copper levels and depression symptoms. It also investigates the effect of modification of BMI (body mass index) on depression symptoms. A total of 5419 US adults aged...
Source: Biological Trace Element Research - November 27, 2022 Category: Biology Authors: Wu Hongrong Li Qingqi Gao Rong Tang Shuangyang Zhang Kaifang Zhao Jianfeng Source Type: research

Association Between Serum Copper and Stroke Risk Factors in Adults: Evidence from the National Health and Nutrition Examination Survey, 2011-2016
This study aimed to examine the relationships between serum copper and lipid levels among 3425 participants aged 20 years and older from the 2011-2016 National Health and Nutrition Examination Survey (NHANES). Data on administered questionnaires, serum copper concentrations, and lipid levels (total cholesterol, HDL cholesterol, triglycerides, and LDL cholesterol) were used. Associations between serum copper and lipid levels were evaluated using both multivariable linear regression and logistic regression models. In the linear regression models, total cholesterol and LDL cholesterol levels increased with increasing copper c...
Source: Biological Trace Element Research - May 6, 2021 Category: Biology Authors: Jingang Xu Guofeng Xu Junkang Fang Source Type: research

Serum Ceruloplasmin Is the Candidate Predictive Biomarker for Acute Aortic Dissection and Is Related to Thrombosed False Lumen: a Propensity Score-Matched Observational Case-Control Study.
Abstract Acute aortic dissection (AAD), one of the fatal diseases observed at the department of vascular surgery, is associated with a great mortality rate at the early stage. Ceruloplasmin (CP) is the plasma protein that functions as a copper transporter. The current retrospective research was carried out to assess CP contents and to examine the possible part in diagnosing patients with AAD. In addition, propensity score matching (PSM) was also utilized for reducing the bias in case screening as well as the clinical confounders. Using PSM, this study included 85 pairs of AAD cases (Stanford A and B dissection) an...
Source: Biological Trace Element Research - June 4, 2020 Category: Biology Authors: Ma C, Zhao H, Shi F, Li M, Liu X, Ji C, Han Y Tags: Biol Trace Elem Res Source Type: research

Association Between Trace Element Status and Depression in HTLV-1-Infected Patients: a Retrospective Cohort Study.
Abstract Depression and Anxiety are two important public health problems that are known to be associated with viral infections. The association between the intake of nutrients such as zinc and copper with symptoms of depression has been studied previously. The aim of the current study was to investigate the association between depression with human T cell lymphotropic virus type 1 (HTLV-1) infection and serum content of zinc and copper in a large Iranian population cohort. The study population consisted of 279 HTLV-1-positive patients who were identified after recruitment as part of a large cohort study: the Mashh...
Source: Biological Trace Element Research - February 4, 2019 Category: Biology Authors: Darroudi S, Abolbashari S, Ahangari N, Tayefi M, Khashyarmanesh Z, Zamani P, Haghighi HM, Mohammadpour AH, Tavalaei S, Esmaily H, Ferns GA, Meshkat Z, Tayefi B, Ghayour-Mobarhan M Tags: Biol Trace Elem Res Source Type: research

Association Between Hypertension in Healthy Participants and Zinc and Copper Status: a Population-Based Study.
Abstract The prevalence of hypertension (HTN) is increasing globally. It has been shown that there is an association between micronutrient deficiency and HTN. In the current study, we aimed to assess the association between HTN with serum copper and zinc concentrations in a large representative Iranian population. The participants were enrolled into the Mashhad stroke and heart atherosclerotic disorders study (MASHAD study), a cohort study that was initiated in 2010. Anthropometric indices were assessed using standard procedures. Systolic (SBP) and diastolic (DBP) blood pressures were measured using a standard mer...
Source: Biological Trace Element Research - September 28, 2018 Category: Biology Authors: Darroudi S, Saberi-Karimian M, Tayefi M, Tayefi B, Khashyarmanesh Z, Fereydouni N, Haghighi HM, Mahmoudi AA, Kharazmi-Khorassani J, Gonoodi K, Esmaeili H, Mohammadpour AH, Ferns GA, Ghayour-Mobarhan M Tags: Biol Trace Elem Res Source Type: research