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Trends in diabetes-related complications in Singapore, 2013 –2020: A registry-based study
ConclusionWe found that DM and its complications represent an important challenge for healthcare in Singapore. Improvements in the trends of DM macrovascular complications were observed. However, trends in DM microvascular complications remain a cause for concern.
Source: PLoS One - October 11, 2022 Category: Biomedical Science Authors: Joshua Kuan Tan Source Type: research

Could prokinetic agents protect long-term nasogastric tube-dependent patients from being hospitalized for pneumonia? A nationwide population-based case-crossover study
ConclusionProkinetic agent use had no negative association with pneumonia admission among long-term nasogastric tube-dependent patients in Taiwan.
Source: PLoS One - April 5, 2021 Category: Biomedical Science Authors: Kun-Siang Huang Source Type: research

Association of digoxin with mortality in patients with advanced chronic kidney disease: A population-based cohort study
In conclusion, our study demonstrated that digoxin use was associated with increased mortality, but not cardiovascular events or renal function decline in advanced CKD patients. This finding warns the safety of presc ribing digoxin in this population. Future prospective studies are needed to overcome the limitations of cohort study design.
Source: PLoS One - January 15, 2021 Category: Biomedical Science Authors: Lii-Jia Yang Source Type: research

Assistive technology using regurgitation fraction and fractional-order integration to assess pulmonary valve insufficiency for pre-surgery decision making and post-surgery outcome evaluation
This study proposes an assistive technology to quantify regurgitation using the regurgitation fraction (RF) and heart pump efficiency (HPE). In signal preprocessing stage, the detrending and zero-crossing processes are used to remove the unwanted flow fluctuations and identify the end-systolic and end-diastolic periods per each cardiac cycle. The fractional-order integrations are employed to calculate the stroke volume (SV) and regurgitation volume (RV). Then, the regurgitation flow can be quantified that indicates the high correlation with HPE. For a mimicking pulmonary circulation loop system, the proposed screening mode...
Source: Biomedical Signal Processing and Control - July 5, 2018 Category: Biomedical Science Source Type: research

Healthy aging of the left ventricle in relationship to cardiovascular risk factors: The Multi-Ethnic Study of Atherosclerosis (MESA)
ConclusionOur results support that LV structure and function are better preserved in senescent hearts in the absence of traditional cardiovascular risk factors, and such protection is more prominent in men than in women.
Source: PLoS One - June 22, 2017 Category: Biomedical Science Authors: Chia-Ying Liu Source Type: research

Stroke and Risks of Development and Progression of Kidney Diseases and End-Stage Renal Disease: A Nationwide Population-Based Cohort Study
by Chia-Lin Wu, Chun-Chieh Tsai, Chew-Teng Kor, Der-Cherng Tarng, Ie-Bin Lian, Tao-Hsiang Yang, Ping-Fang Chiu, Chia-Chu Chang Background There is little information about the association between stroke and kidney diseases. We aimed to investigate the impact of stroke on long-term renal outcomes. Methods In this large population-based retrospective cohort study, we identified 100,353 subjects registered in the National Health Insurance Research Database of Taiwan from January 1, 2000, through December 31, 2012, including 33,451 stroke patients and 66,902 age-, sex- and Charlson’s comorbidity index score-matched controls....
Source: PLoS One - June 28, 2016 Category: Biomedical Science Authors: Chia-Lin Wu Source Type: research