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Validating Laboratory Results in a National Observational Cohort Study without Field Centers: the Reasons for Geographic and Racial Disparities in Stroke Cohort.
CONCLUSIONS: Simulation of non-optimal field processing and shipment to a central laboratory showed high variability in analytes released by platelets. The majority of other analytes produced valid results, but platelet contamination in REGARDS samples makes measurement of platelet proteins unadvisable in these samples. Future analytes considered by REGARDS or similar studies should undergo similar pilot testing. PMID: 25130959 [PubMed - as supplied by publisher]
Source: Clinical Biochemistry - August 14, 2014 Category: Biochemistry Authors: Gillett SR, Boyle RH, Zakai NA, McClure LA, Jenny NS, Cushman M Tags: Clin Biochem Source Type: research