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Apolipoprotein E polymorphism and cerebral stroke.
Conclusions: The distribution of allelic frequencies of apolipoprotein E in the population of Constantine is similar to that of Southern Europe. Our results imply a role of the genotype of apolipoprotein E (ɛ4 allele) in the pathogenesis of stroke and are limited to the accidents of the ischemic type. The ɛ2 allele does not appear to be implied in occurred of this affection; however, large additional studies are necessary to confirm this result. PMID: 23396426 [PubMed - as supplied by publisher]
Source: Annales de Biologie Clinique - February 1, 2013 Category: Biochemistry Authors: Boumendjel S, Khodja D, Hamri A, Benlatreche C, Abadi N Tags: Ann Biol Clin (Paris) Source Type: research