• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Mitochondrial variations in the MT-ND4 and MT-TL1 genes are associated with male infertility.
Abstract Mitochondrial gene mutations have been reported to be associated with sperm motility and the quality of semen. The aim of this study was to investigate whether the two mitochondrial genes (MT-ND4 and MT-TL1) are involved in Chinese male infertility. A total of 97 asthenospermia patients and 80 fertile controls were recruited in this case-control study. Genomic DNA were extracted from the sperm of all participants. Two mitochondrial DNA genes (MT-ND4 and MT-TL1) were amplified by using polymerase chain reaction (PCR) with the gene-specific primers and sequenced on an ABI 3730XL DNA sequencer. For the MT-ND...
Source: Systems Biology in Reproductive Medicine - December 13, 2016 Category: Reproduction Medicine Authors: Ni F, Zhou Y, Zhang WX, Wang XM, Song XM, Jiang H Tags: Syst Biol Reprod Med Source Type: research