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Staff’s views on delivering patient-led therapy during inpatient stroke rehabilitation: a focus group study with lessons for trial fidelity
Conclusions: Delivering rehabilitation interventions within a trial is complex. Staff require time and support to develop the skills, strategies and confidence to identify suitable patients, deliver new treatments, adapt the new treatments to individuals’ needs and balance the demands of delivering the trial intervention according to the treatment protocol with other clinical and professional priorities.Trial registrationISRCTN: ISRCTN29533052. October 2011.
Source: Epidemiologic Perspectives and Innovations - April 7, 2015 Category: Epidemiology Authors: Maria HorneNessa ThomasAndy VailRudd SellesCandy McCabeSarah Tyson Source Type: research

Limitations of within-person study designs
Within-person study designs have been increasingly used because they offer the potential to control for the confounding that arises from systematic differences between the characteristics of exposed and unexposed individuals. Our recent study illustrates several limitations of within-person study designs. Farrington's comment concurs with our assertion that the self-controlled case series (SCCS) study will generally be invalid when there is censoring on outcome for, as we note in the introduction to our article (p385), “Bias may arise if the outcome event leads to censoring.” Our results confirm empirically that “th...
Source: Journal of Clinical Epidemiology - September 5, 2013 Category: Epidemiology Authors: Jennifer M. Nicholas, Andrew P. Grieve, Martin C. Gulliford Tags: Letters to the Editor Source Type: research