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Plexus anesthesia versus general anesthesia for carotid endarterectomy: A systematic review with meta-analyses
CONCLUSIONS: Based on the current, high risk of bias evidence, we concluded there is a need for new randomized clinical trials with overall low risk of bias comparing plexus anesthesia with general anesthesia in carotid endarterectomy with patch closure of the arterial wall in patients with a symptomatic and significant (≥50%) stenosis of the internal carotid artery.Protocol unique identification number (UIN): CRD42019139913, (https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=139913).PMID:33996058 | PMC:PMC8094902 | DOI:10.1016/j.amsu.2021.102327
Source: Annals of Medicine - May 17, 2021 Category: Internal Medicine Authors: M S Marsman J Wetterslev F Keus D van Aalst F G van Rooij J M M Heyligers F L Moll A Kh Jahrome P W H E Vriens G G Koning Source Type: research

Morphology and histology of silent and symptom-causing atherosclerotic carotid plaques - Rationale and design of the Helsinki Carotid Endarterectomy Study 2 (the HeCES2).
This article provides a detailed study design and protocol of HeCES2, an observational prospective cohort study with the objective to investigate the pathophysiology of carotid atherosclerosis. MATERIALS AND METHODS: Recruitment and carotid endarterectomies of the study patients with carotid atherosclerosis were performed from October 2012 to September 2015. After brain and carotid artery imaging, endarterectomised carotid plaques (CPs) and blood samples were collected from 500 patients for detailed biochemical and molecular analyses. Findings to date: We developed a morphological grading for macroscopic characteristic...
Source: Annals of Medicine - July 18, 2018 Category: Internal Medicine Tags: Ann Med Source Type: research