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Association of beta-2-microglobulin, cystatin C and lipocalin-2 with stroke risk in the general Chinese population
CONCLUSION: Elevated serum B2M, cystatin C and LCN-2 levels are associated with stroke risk. They may be novel biomarkers for clinicians to assess stroke risk.Key messagesSerum beta-2-microglobulin, cystatin C and lipocalin-2 levels are significantly associated with stroke risk.Beta-2-microglobulin, cystatin C and lipocalin-2 may serve as useful biomarkers for stroke risk stratification in the general population.PMID:37155257 | PMC:PMC10167872 | DOI:10.1080/07853890.2023.2203516
Source: Annals of Medicine - May 8, 2023 Category: Internal Medicine Authors: Juanying Zhen Shuyun Liu Ryan Yan Lam Kam Guoru Zhao Hao Peng Jianguo Liang Aimin Xu Chao Li Lijie Ren Jun Wu Bernard Man Yung Cheung Source Type: research

Correlation between dietary selenium intake and stroke in the National Health and Nutrition Examination Survey 2003-2018
CONCLUSIONS: Dietary selenium had a negative and non-linear correlation with the risk of stroke in adults. The correlation varied across different population subgroups.KEY MESSAGESDietary selenium had a negative and non-linear correlation with the risk of stroke in adults.Non-linear negative correlation trends were observed in subpopulations of females, age <60 years, poverty-income ratio <2.14, overweight and obesity, hypertension, non-diabetes, and non-anaemia.Dietary selenium intake of approximately 105 μg per day has an optimum effect on stroke.PMID:35594240 | DOI:10.1080/07853890.2022.2058079
Source: Annals of Medicine - May 20, 2022 Category: Internal Medicine Authors: Wenrui Shi Liang Su Jian Wang Fangze Wang Xu Liu Jianxin Dou Source Type: research

Role of female community health volunteers in ischemic stroke prevention, identification, referral and rehabilitation in Nepal
Ann Med Surg (Lond). 2021 Oct 8;72:102893. doi: 10.1016/j.amsu.2021.102893. eCollection 2021 Dec.ABSTRACTFor the past three decades, female community health volunteers (FCHVs) have been at the forefront of Nepal's health map and have contributed significantly to its improving health indicators such as maternal mortality rate and infant mortality rate. Given the changing epidemiology of Nepal and the shift of burden from communicable to non-communicable diseases (NCDs), it is important to revitalize their role with the changing times. The prevalence of ischemic stroke in Nepal is on the rise. However, very few people make i...
Source: Annals of Medicine - January 7, 2022 Category: Internal Medicine Authors: Babin Basnet Jayant Kumar Yadav Bikram Prasad Gajurel Yow Ka Shing Bipin Kandel Gaurav Nepal Source Type: research

The Effects of Body Mass Index on In-hospital mortality following first ischemic or hemorrhagic stroke events: Does the "obesity paradox" apply?
CONCLUSION: Obese patients are less likely to die during hospitalization following first-time non-subarachnoid hemorrhage and ischemic stroke than non-overweight/non-obese patients. These findings support the "obesity paradox" concept, though more research is needed for recurrent stroke patients.PMID:34691415 | PMC:PMC8519764 | DOI:10.1016/j.amsu.2021.102839
Source: Annals of Medicine - October 25, 2021 Category: Internal Medicine Authors: Kevin J Kinter Robert Alfaro Christopher Kinter Lucas Suder Zachary Davis Pura Rodriguez Juan Gabriel Ruiz Juan Carlos Zevallos Adel Elkbuli Source Type: research

Influence of changes in body fat on clinical outcomes in a general population: a 12-year follow-up report on the Ansan-Ansung cohort in the Korean Genome Environment Study
CONCLUSION: Increasing BF was associated with a lower risk of all-cause death, cardiovascular death, and MACE in the general population.Key messagesIncreasing body fat is associated with a lower risk of all-cause death, cardiovascular death, and major cardiovascular adverse events in a low-risk ageing general population, independently of physical activity, underlying cardiovascular disease burden, changes in muscle mass, and baseline obesity status.Fatness measured at baseline requires adjustment for the changes in fatness during the follow-up to reveal its impact on the clinical outcomes.PMID:34533069 | PMC:PMC8451655 | D...
Source: Annals of Medicine - September 17, 2021 Category: Internal Medicine Authors: Byung Sik Kim Yonggu Lee Hyun-Jin Kim Jeong-Hun Shin Jin-Kyu Park Hwan-Cheol Park Young-Hyo Lim Jinho Shin Source Type: research

The association of non-alcoholic fatty liver disease and atrial fibrillation: a review.
Authors: Juhani Käräjämäki A, Hukkanen J, Ukkola O Abstract Non-alcoholic fatty liver disease (NAFLD) is highly prevalent and causes an enormous burden to human health and health-care systems all over the world. A great proportion of this burden results from increased risk of cardiovascular diseases. Atrial fibrillation (AF) is the most common chronic heart arrhythmia globally and it increases the risk of embolic stroke and heart failure. Recent studies have explored the association between NAFLD and AF with somewhat conflicting results. However, ultrasound-verified prospective studies concur that NAFLD is asso...
Source: Annals of Medicine - June 26, 2018 Category: Internal Medicine Tags: Ann Med Source Type: research

Diabetes and new-onset atrial fibrillation in a hypertensive population.
CONCLUSION: Diabetes was modestly associated with new-onset AF in hypertensive patients with no ischemic vascular disease. Among diabetic patients, only obesity reached significance in its association with this arrhythmia. PMID: 26939743 [PubMed - indexed for MEDLINE]
Source: Annals of Medicine - January 1, 2017 Category: Internal Medicine Tags: Ann Med Source Type: research

Obstructive sleep apnea risk and psychological health among non-Hispanic blacks in the Metabolic Syndrome Outcome (MetSO) cohort study.
Conclusion Our results suggest that non-Hispanic blacks with metabolic syndrome who experience anxiety and/or depression should be screened for OSA. Key messages This study assessed associations of moderate to severe depression and anxiety with risk of obstructive sleep apnea (OSA) among non-Hispanic blacks with metabolic syndrome. Patients with depression had nearly two-fold increased odds of being at risk for OSA. Patients with anxiety had three-fold increased odds of being at risk for OSA. PMID: 26593384 [PubMed - in process]
Source: Annals of Medicine - February 18, 2016 Category: Internal Medicine Tags: Ann Med Source Type: research

Significant interactions between traditional risk factors affect cardiovascular risk prediction in healthy general population.
CONCLUSIONS: There are significant effect modifications between major risk factors, and accounting for them leads to significantly more accurate estimation of cardiovascular risk. PMID: 25405541 [PubMed - indexed for MEDLINE]
Source: Annals of Medicine - February 18, 2016 Category: Internal Medicine Tags: Ann Med Source Type: research