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Efficacy of ablation therapy on clinical outcomes in patients with atrial fibrillation: a systematic review and meta-analysis
CONCLUSION: Ablation significantly reduces the risk of stroke, cardiovascular mortality, all-cause mortality, and HF in AF patients, compared with medical therapy alone, supporting its use in clinical practice.PMID:37663739 | PMC:PMC10473299 | DOI:10.1097/MS9.0000000000000985
Source: Annals of Medicine - September 4, 2023 Category: Internal Medicine Authors: Mohammad Munim Zahoor Saad Ehsan Ullah Harriet Mmaitsi Kidiavai Shahda A H Eltieb Anjuli Devi Muhammad Anis Asif Akshay Vaswani Ammar Hyder Muhammad Roshan Hoti Sayed Jawad Sana Arshid Abhirami Shankar Muhammad Salman Source Type: research

Warfarin-induced isolated spontaneous subarachnoid hemorrhage: Rare case report
CONCLUSION: Warfarin is rarely associated with isolated subarachnoid hemorrhage. This case highlights a young male patient with spontaneous SAH after warfarin therapy for acute ischemic stroke. Aneurysmal rupture and trauma should be excluded before a diagnosis of warfarin-induced SAH is made.PMID:36582886 | PMC:PMC9793204 | DOI:10.1016/j.amsu.2022.104946
Source: Annals of Medicine - December 30, 2022 Category: Internal Medicine Authors: Mohamed Sheikh Hassan Ahmet Bakir Bakar Ali Adam Nor Osman Sidow Abdiwahid Ahmed Ibrahim Ishak Ahmed Abdi Mohamud Mire Waberi Source Type: research

Impact of thyroid disease in patients with atrial fibrillation: Analysis from the JoFib registry
CONCLUSION: Despite having similar stroke and bleeding risks, patients with thyroid disease demonstrated meaningful differences in their baseline characteristics. Prospective studies are required to assess the influence of thyroid hormone fluctuations on the progression of AF.PMID:35145683 | PMC:PMC8818533 | DOI:10.1016/j.amsu.2022.103325
Source: Annals of Medicine - February 11, 2022 Category: Internal Medicine Authors: Hanna Al-Makhamreh Abdallah Al-Ani Dana Alkhulaifat Liza Shaban Neveen Salah Rusul Almarayaty Yazan Al-Huneidy Ayman Hammoudeh Source Type: research

Prognostic value of GRACE and CHA2DS2-VASc score among patients with atrial fibrillation undergoing percutaneous coronary intervention
CONCLUSIONS: High GRACE score but not CHA2DS2-VASc score were both associated with an increased risk of MACEs after PCI in patients with AF. The GRACE and CHA2DS2-VASc scores have similar predictive performance for predicting all-cause mortality.Key messages:In patients with AF undergoing PCI, increasing GRACE but not CHA2DS2-VASc scores was independently associated high risk of MACEs.The GRACE score could also help identify patients at higher risk of stroke and major bleeding.Both GRACE and CHA2DS2-VASc scores showed good ability in the prediction of all-cause mortality.PMID:34791980 | DOI:10.1080/07853890.2021.2004321
Source: Annals of Medicine - November 18, 2021 Category: Internal Medicine Authors: Tingting Guo Ziwei Xi Hong Qiu Yong Wang Jianfeng Zheng Kefei Dou Bo Xu Shubin Qiao Weixian Yang Runlin Gao Source Type: research

Risk profile, antithrombotic treatment and clinical outcomes of patients in Nordic countries with atrial fibrillation - results from the GARFIELD-AF registry
CONCLUSION: Nordic patients had significantly higher major bleeding than Non-Nordic-European patients. In contrast, rates of all-cause mortality and non-haemorrhagic stroke/SE were comparable.CLINICAL TRIAL REGISTRATION: Unique identifier: NCT01090362. URL: http://www.clinicaltrials.gov.KEY MESSAGE: Nordic countries had significantly higher major bleeding than Non-Nordic-European countries. Rates of mortality and non-haemorrhagic stroke/SE were similar .PMID:33818226 | DOI:10.1080/07853890.2021.1893897
Source: Annals of Medicine - April 5, 2021 Category: Internal Medicine Authors: Marita Knudsen Pope Dan Atar Arne Svilaas Torstein Hole J ørn Dalsgaard Nielsen Ulrik Hintze Milita Crisby Pekka Raatikainen K E Juhani Airaksinen Saverio Virdone Karen Pieper Gloria Kayani Jean-Yves Le Heuzey Jan Steffel Janina Stepinska Jean-Pierre Bas Source Type: research

Thoracic endovascular aortic repair versus open chest surgical repair for patients with type B aortic dissection: A systematic review and meta-analysis.
Conclusions: The findings of this meta-analysis study suggested that TEVAR resulted in more short-term survival benefits. Moreover, the reduced risk of acute renal failure, respiratory failure and bleeding was detected in TEVAR group. The treatment effects of TEVAR versus OCSR on specific complications should be further verified by a study with high-level of evidence. Key message Comprehensive collected studies investigated the treatment effectiveness between TEVAR and OCSR for TBAD patients TEVAR resulted in more survival benefits, in addition to lower risk of acute renal failure, respiratory failure and bleeding The resu...
Source: Annals of Medicine - October 12, 2019 Category: Internal Medicine Tags: Ann Med Source Type: research

Fitting the right non-vitamin K antagonist oral anticoagulant to the right patient with non-valvular atrial fibrillation: An evidence-based choice.
Authors: Li Y, Pastori D, Lip GY Abstract Atrial fibrillation (AF) is the most prevalent arrhythmia and is associated with an increased risk of ischemic stroke (IS) and systemic embolism (SE). Stroke prevention is a key element for the overall management of AF patients. The non-vitamin K antagonist oral anticoagulants (NOACs), such as dabigatran, rivaroxaban, apixaban and edoxaban, are at least as effective as warfarin in reducing IS/SE with a lower rate of major bleeding. Various analyses from the large Phase III randomised trials demonstrated different efficacy and safety of NOACs in specific subgroups of patient...
Source: Annals of Medicine - April 4, 2018 Category: Internal Medicine Tags: Ann Med Source Type: research

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