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Ateplase for ischaemic stroke: increased risk of intracranial haemorrhage is balanced by improved stroke outcomes, particularly if treated within 3-4.5 h of onset
Commentary on: Emberson J, Lees KR, Lyden P, et al., Stroke Thrombolysis Trialists’ Collaborative Group. Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials. Lancet 2014;384:1929–35. Implications for practice and research Thrombolysis given to appropriate patients within 4.5 h of the onset of stroke symptoms increases the chance of a good outcome. The earlier it is given, the more likely it is to be effective. Thrombolysis increases the risk of early death,...
Source: Evidence-Based Nursing - September 21, 2015 Category: Nursing Authors: Rudd, A. Tags: Drugs: cardiovascular system, Stroke, Ischaemic heart disease, Clinical diagnostic tests Adult nursing Source Type: research

Quality of life and caregiver outcomes following decompressive hemicraniectomy for severe stroke: a narrative literature review.
CONCLUSION: Most patients and caregivers in the studies reviewed agreed with the original decision to undergo DHC and would make the same decision again. However, little is known about quality of life for both patients and caregivers and caregiver burden over the long-term post-surgery. Further research is needed to generate information and interventions for the management of ongoing patient and carer recovery following DHC for severe stroke. PMID: 20533642 [PubMed - indexed for MEDLINE]
Source: Canadian Journal of Neuroscience Nursing - November 18, 2015 Category: Nursing Tags: Can J Neurosci Nurs Source Type: research

Thrombocytopenia: Effect in Ischemic and Hemorrhagic Stroke
CONCLUSION: Acknowledging the impact of both platelet and thrombocytopenia on stroke causation, stroke interventions, and outcomes is a pivotal aspect of comprehensive stroke care. Platelet function processes are impactful in each point of the continuum of stroke care, prevention, intervention, and discharge.PMID:33792271 | DOI:10.1097/DCC.0000000000000471
Source: Dimensions in Critical Care Nursing - April 1, 2021 Category: Nursing Authors: Angela Smith Collins Yoder Cheryl B Hines Source Type: research

Research on the Cause of Death for Severe Stroke Patients
ConclusionsThe most common cause of death in stroke patients was damage to the central nervous system. Independent risk factors were brain herniation, multiple organ failure, dyslipidemia, community‐acquired lung infection, the use of mechanical ventilation, hypoproteinemia, a history of hypertension, and hospital‐acquired pneumonia. Clinicians should be aware of the presence and possible effects of these conditions. Early prevention, monitoring and intervention to modify controllable risk factors will improve patient prognosis. Relevance to clinical practiceClinicians should be aware of the multiple independent risk f...
Source: Journal of Clinical Nursing - July 5, 2017 Category: Nursing Authors: Mei ‐zhen Yuan, Feng Li, Qin Fang, Wei Wang, Jing‐jing Peng, De‐yu Qin, Xue‐feng Wang, Guang‐wei Liu Tags: Original Article Source Type: research

Predictors of prolonged hospital stay in a Comprehensive Stroke Unit.
CONCLUSION: this study showed that three complications delayed hospital discharge in patients admitted in a stroke unit, two preventable ones: pneumonia and urinary tract infection. More intense measures to avoid them should be included in the performance indicators to reduce the length of hospital stay in stroke units. PMID: 31618390 [PubMed - in process]
Source: Revista Latino-Americana de Enfermagem - October 13, 2019 Category: Nursing Authors: Gaspari AP, Cruz EDA, Batista J, Alpendre FT, Zétola V, Lange MC Tags: Rev Lat Am Enfermagem Source Type: research

Mobile stroke units: taking stroke care to the patient
Purpose of review Since the development of intravenous tissue plasminogen activator (tPA) for acute ischemic stroke (AIS), functional outcome has improved when treatment occurs within 4.5 h of stroke onset and treatment benefits are greater with earlier treatment. Endovascular revascularization also is better the sooner it is delivered. Recent findings The Get with the Guidelines Stroke registry found that less than one-third of treatment-eligible AIS patients receive intravenous tPA within 60 min of hospital arrival. Initiatives have tried to improve public education and awareness of stroke symptoms to decrease t...
Source: Current Opinion in Critical Care - March 6, 2020 Category: Nursing Tags: ACUTE NEUROLOGICAL PROBLEMS: Edited by Peter Le Roux Source Type: research

Acute Ischemic Stroke
This article discusses the pathophysiology underlying the various types of ischemic stroke; the risk factors for ischemic stroke; stroke presentation; and the evidence-based treatments, nursing assessments, and monitoring protocols that are critical to patient recovery.PMID:34402461 | DOI:10.1097/01.NAJ.0000790184.66496.1d
Source: The American Journal of Nursing - August 17, 2021 Category: Nursing Authors: Nneka Lotea Ifejika Heather H Washington Kimberly R Glaser Source Type: research

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