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Comparing 5G mobile stroke unit and emergency medical service in patients acute ischemic stroke eligible for t ‐PA treatment: A prospective, single‐center clinical trial in Ya'an, China
ConclusionsOur findings indicate that 5G MSU care significantly reduces the time from symptom onset to stroke diagnosis and intravenous thrombolysis in patients with AIS, resulting in improved functional outcomes compared to EMS care. As China continues its deployment of 5G technology and other digital infrastructures, the adoption of 5G MSU care on a broader scale may eventually supplant traditional stroke treatment approaches.
Source: Brain and Behavior - August 26, 2023 Category: Neurology Authors: Bo Zheng, Yan Li, Gangfeng Gu, Jian Yang, Junyao Jiang, Zhao Chen, Yang Fan, Sheng Wang, Han Pei, Jian Wang Tags: ORIGINAL ARTICLE Source Type: research

Effects of predictive nursing intervention on cognitive impairment and neurological function in ischemic stroke patients
ConclusionPredictive nursing intervention is beneficial to improve the effects of thrombolytic therapy in patients with ischemic stroke, which improves the neurological, cognitive and motor functions of patients, and reduces the occurrence of complications, suggesting an important clinical application value.
Source: Brain and Behavior - February 4, 2023 Category: Neurology Authors: Lianyu Xue, Jiangshan Deng, Lingyan Zhu, Feifei Shen, Jiewei Wei, Lihui Wang, Qinqin Chen, Lan Wang Tags: ORIGINAL ARTICLE Source Type: research

Successful thrombolytic therapy is associated with increased granulocyte CD15 expression and reduced stroke ‐induced immunosuppression
ConclusionsOur current results indicate that TT may not only acutely reduce the systemic inflammatory response following stroke but may also play a role in reversing SIIS at a later stage following the insult, as reflected by the higher expression of the CD15 marker on granulocytes following successful TT.
Source: Brain and Behavior - September 16, 2022 Category: Neurology Authors: Katalin Anna B éres‐Molnár, Ágnes Czeti, Ferenc Takács, Gábor Barna, Dániel Kis, Gabriella Róka, András Folyovich, Gergely Toldi Tags: ORIGINAL ARTICLE Source Type: research

A fibrin targeted molecular imaging evaluation of microvascular no ‐reflow in acute ischemic stroke
ConclusionFibrin deposition and stacked RBCs contribute to microcirculation no-reflow in AIS after thrombolytic therapy.
Source: Brain and Behavior - January 13, 2022 Category: Neurology Authors: Xi Chen, Jing Wang, Liang Ge, Gang Lu, Hailin Wan, Yeqing Jiang, Zhenwei Yao, Gang Deng, Xiaolong Zhang Tags: ORIGINAL ARTICLE Source Type: research

Hyperdense middle cerebral artery sign in large cerebral infarction
ConclusionsHMCAS in patients with a large cerebral infarction without thrombolytic therapy is an independent biomarker of HT. Length of HMCAS is also a marker of HT with lower ASPECTS in HMCAS patients.
Source: Brain and Behavior - March 25, 2021 Category: Neurology Authors: Jie Hou, Yu Sun, Yang Duan, Libo Zhang, Dengxiang Xing, Xiaoqiu Lee, Benqiang Yang Tags: ORIGINAL RESEARCH Source Type: research

Neutrophil –lymphocyte ratio predicts post‐thrombolysis early neurological deterioration in acute ischemic stroke patients
ConclusionsThis study showed that elevated level of NLR may predict post ‐thrombolysis END in ischemic stroke patients.
Source: Brain and Behavior - September 29, 2019 Category: Neurology Authors: Pengyu Gong, Yi Xie, Teng Jiang, Yukai Liu, Meng Wang, Huanhuan Sun, Shuting Zhang, Yingdong Zhang, Xiaohao Zhang, Junshan Zhou Tags: ORIGINAL RESEARCH Source Type: research

The rate of early neurological deterioration occurring after thrombolytic therapy: A meta ‐analysis
ConclusionThe rate of END occurring after thrombolytic  therapy is about 11.0%. This finding may provide a scientific reference for researchers to evaluate the efficacy and safety of thrombolytic therapy.
Source: Brain and Behavior - January 10, 2019 Category: Neurology Authors: Xiaowen Hou, Wanli Chen, Haibin Xu, Zhi Zhu, Yuanyuan Xu, Huisheng Chen Tags: ORIGINAL RESEARCH Source Type: research

Risk of pneumonia associated with zero‐degree head positioning in acute ischemic stroke patients treated with intravenous tissue plasminogen activator
ConclusionsZero‐degree head of bed positioning in the first 24 h following an acute ischemic stroke treated with IV‐tPA was associated with acceptable rates of pneumonia. Rates for pneumonia may be further reduced by eliminating use of a 0° protocol in intubated/mechanically ventilated patients. A zero‐degree head of bed position is recommended to increase cerebral perfusion in nonhypoxic acute ischemic stroke patients able to tolerate lying flat. However, this is not uniformly applied in clinical practice, most likely due to concerns of aspiration pneumonia. In our retrospective descriptive study, zero‐degree p...
Source: Brain and Behavior - December 1, 2015 Category: Neurology Authors: Paola Palazzo, Amy Brooks, David James, Randy Moore, Andrei V. Alexandrov, Anne W. Alexandrov Tags: Original Research Source Type: research