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Risk of readmission and mortality in patients with ischaemic stroke
Morton et al. conducted a 1-year follow-up study to evaluate the risk of readmission to hospital and all-cause mortality in patients with ischaemic stroke (IS) [1]. The cumulative incidence of all-cause readmission was 56.1%, and the adjusted hazard ratios (HRs) (95% confidence intervals [CI]) of patients with diabetes for all-cause, cardiovascular, and IS readmission were 1.13 (1.09 –1.17), 1.14 (1.07–1.21), and 1.17 (1.06–1.29). One-year mortality also increased significantly in patients with diabetes, and IS readmission and mortality were higher in women than those in men.
Source: Journal of the Neurological Sciences - September 30, 2022 Category: Neurology Authors: Tomoyuiki Kawada Source Type: research

One-year readmission and mortality following ischaemic stroke by diabetes status, sex, and socioeconomic disadvantage: An analysis of 27,802 strokes from 2012 to 2017
We estimated the 1-year incidence of readmission to hospital and 1-year all-cause mortality following ischaemic stroke (IS), by diabetes status, sex, and socioeconomic disadvantage.
Source: Journal of the Neurological Sciences - January 12, 2022 Category: Neurology Authors: Jedidiah I. Morton, Jenni Ilom äki, Stephen J. Wood, J. Simon Bell, Jonathan E. Shaw, Dianna J. Magliano Source Type: research

A one-year longitudinal evaluation of cerebrospinal fluid and blood neurochemical markers in a patient with cryptococcal meningitis complicated by ischemic stroke.
Cryptococcal meningitis (CCM) is caused by the encapsulated basidiomycetous yeast Cryptococcus neoformans and is one of the most common central nervous system (CNS) infections in immunocompromised subjects [1 –4]. In this regard, autoimmune diseases, sarcoidosis, glucocorticoid treatment, solid-organ transplantation, hematologic malignancies, diabetes mellitus, chronic renal failure are well-known predisposing factors for CCM in HIV-negative patients [1–4]. Sources of C. neoformans are excrement of b irds such as pigeons, contaminated soil, and the bark of several tree species [1].
Source: Journal of the Neurological Sciences - December 13, 2021 Category: Neurology Authors: Samir Abu-Rumeileh, Tamara Garibashvili, J ürgen Benjamin Hagemann, Veronika Still, Franziska Bachhuber, Markus Otto, Hayrettin Tumani, Makbule Senel Tags: Letter to the Editor Source Type: research

Characterisation of recent trends in cardiovascular risk factors in young and middle-aged patients with ischaemic stroke and/or transient ischaemic attack
Strokes in the young and middle-aged are associated with a disproportionately large economic and social impact in addition to their clinical effects. Standard Modifiable Cardiovascular Risk Factors (SMuRFs; hypercholesterolaemia, hypertension, diabetes mellitus and smoking) are key drivers of cardiovascular disease including strokes, however recent temporal trends in the younger stroke population have not been well characterised. We aimed to evaluate recent trends of SMuRFs in a cohort of younger patients with ischaemic stroke.
Source: Journal of the Neurological Sciences - September 1, 2020 Category: Neurology Authors: Aditya Bhat, Gary C.H. Gan, David Makarious, Elizabeth Tan, Henry H.L. Chen, Nigel Wolfe, Lina Lee, Camelia Burdusel, Maria Carmo P. Nunes, Clara K. Chow, Timothy C. Tan Source Type: research

Prevalence and predictors of statin utilization among patient populations at high vascular risk in Ghana
Inadequate implementation of evidence-based preventive measures for individuals at high risk of cardiovascular disease (CVD) will only worsen the current epidemic of CVDs in sub-Saharan Africa. We assessed rates and predictors of statin utilization among two high CVD risk patient populations, people with type 2 diabetes mellitus (T2DM) and those with stroke, encountered across five hospitals in Ghana.
Source: Journal of the Neurological Sciences - April 14, 2020 Category: Neurology Authors: Fred Stephen Sarfo, Bruce Ovbiagele Source Type: research

Sleep disorders and disrupted sleep in addiction, withdrawal and abstinence with focus on alcohol and opioids
Sleep is very important for our physical and mental health. Sleep disturbances increase risk of substance use disorders as well as risk of onset and worsening of medical and other primary psychiatric problems like diabetes, kidney disease, high blood pressure, heart disease, stroke, and depression [1,2]. Substance use disorders, particularly alcohol and opioids can cause or exacerbate sleep disturbances [3,4] leading to even greater problems with our health in addition to the consequences of substance use [1,2].
Source: Journal of the Neurological Sciences - January 29, 2020 Category: Neurology Authors: William-Bernard Reid-Varley, Caridad Ponce-Martinez, Khurshid A. Khurshid Tags: Review Article Source Type: research

Low heteroplasmy rates in clinically affected m.3243A   >  G carriers not necessarily explain the phenotype
In a recent article, Liu et al. reported about 17 patients from 7 Han families all carrying the m.3243A  > G variant who manifested phenotypically with mitochondrial leukoencephalopathy, lactic acidosis, and stroke-like episodes (MELAS) (n = 5), myopathy (n = 2), neuropathy, ataxia, and retinitis pigmentosa (NARP) (n = 1), diabetes (n = 6), and hypoacusis (n = 3) [1]. Heteroplasmy rates in bl ood lymphocytes in these patients were highly variable, discordant to the clinical manifestations [1]. Among the clinically manifesting mutation carriers mutation loads ranged between 0 and 79% [1].
Source: Journal of the Neurological Sciences - December 4, 2019 Category: Neurology Authors: Josef Finsterer Tags: Letter to the Editor Source Type: research

Low heteroplasmy rates in clinically affected m.3243A   >  G carriers not necessarily explain the phenotype
In a recent article, Liu et al. reported about 17 patients from 7 Han families all carrying the m.3243A  > G variant who manifested phenotypically with mitochondrial leukoencephalopathy, lactic acidosis, and stroke-like episodes (MELAS) (n = 5), myopathy (n = 2), neuropathy, ataxia, and retinitis pigmentosa (NARP) (n = 1), diabetes (n = 6), and hypoacusis (n = 3) [1]. Heteroplasmy rates in blood lymphocytes in these patients were highly variable, discordant to the clinical manifestations [1]. Among the clinically manifesting mutation carriers mutation loads ranged between 0 and 79% [1].
Source: Journal of the Neurological Sciences - December 4, 2019 Category: Neurology Authors: Josef Finsterer Tags: Letter to the Editor Source Type: research

Serum cholesterol, body mass index and smoking status do not predict long-term cognitive impairment in stroke elderly patients
Older stroke survivors are at risk of long-term cognitive impairment, which is associated with a number of modifiable and non-modifiable factors. We aimed to assess the association between the modifiable risk factors, serum cholesterol, low density lipoprotein, high density lipoprotein, serum triglycerides, body mass index (BMI) and smoking status on cognitive function, while controlling for the non-modifiable factors, acute functional impairment, diabetes status and age.
Source: Journal of the Neurological Sciences - September 13, 2019 Category: Neurology Authors: MichaelaC. Pascoe, Chantal F. Ski, David R. Thompson, Thomas Linden Source Type: research

Estimated glomerular filtration rate and incident stroke in patients with hypertension and/or diabetes
Sarfo et al. conducted a prospective study to evaluate the effect of estimated glomerular filtration rate (eGFR) on incident stroke in patients with hypertension and/or type 2 diabetes mellitus [1]. The authors had reported the risk factors of incident stroke in patients with hypertension and/or type 2 diabetes mellitus by using the same database [2]. They recognized 54 events of stroke and stroke incidence rates increased with decreasing eGFR. Adjusted hazard ratios (HRs) (95% confidence intervals [CIs]) of eGFR with 60 –89 ml/min, 30–59 ml/min, and89  ml/min for incident stroke were 1.42 (0.63–3.21), 1.88 (1....
Source: Journal of the Neurological Sciences - December 27, 2018 Category: Neurology Authors: Tomoyuki Kawada Tags: Letter to the Editor Source Type: research

Response by Sarfo to letter regarding “Patients with hypertension and/or diabetes and incident stroke: A risk assessment”
We sincerely thank Dr. Kawada for his interest in our study titled ‘Incident stroke among Ghanaians with hypertension and diabetes: a multicenter, prospective study’. The aim of our study [1] was to assess the rates and determinants of incident stroke among a prospective, hospital-based Ghanaian cohort with hypertension and or type 2 diabetes mellitus. In this regard, our study was not designed to “evaluate the risk of hypertension and diabetes for incident stroke” as specified by our correspondents.
Source: Journal of the Neurological Sciences - December 13, 2018 Category: Neurology Authors: Fred S. Sarfo Tags: Letter to the Editor Source Type: research

Patients with hypertension and/or diabetes and incident stroke: A risk assessment
Sarfo et al. conducted a prospective study to evaluate the risk of hypertension and diabetes for incident stroke [1]. The authors recognized 54 events of stroke, and incidence rates (95% confidence intervals [CIs]) of stroke per 1000 person-years in patients with diabetes and hypertension, only hypertension and only diabetes were 16.64 (10.58 –25.00), 13.77 (9.33–19.64) and 9.81 (3.59–21.74), respectively. In addition, adjusted hazard ratios (95% CI) of previous cigarette smoking and physical inactivity for incident stroke were 2.59 (1.18–5.67) and 1.81 (1.06–3.10).
Source: Journal of the Neurological Sciences - December 13, 2018 Category: Neurology Authors: Tomoyuki Kawada Tags: Letter to the Editor Source Type: research

Estimated glomerular filtration rate predicts incident stroke among Ghanaians with diabetes and hypertension
This study sought to fill this knowledge gap.
Source: Journal of the Neurological Sciences - November 15, 2018 Category: Neurology Authors: Fred Stephen Sarfo, Linda Meta Mobula, Osei Sarfo-Kantanka, Sheila Adamu, Jacob Plange-Rhule, Daniel Ansong, Rexford Adu Gyamfi, James Duah, Bertha Abraham, David Ofori-Adjei Tags: Clinical short communication Source Type: research

WITHDRAWN: Estimated glomerular filtration rate predicts incident stroke among ghanaians with diabetes and hypertension
This article has been withdrawn at the request of the editor. The Publisher apologizes for any inconvenience this may cause.
Source: Journal of the Neurological Sciences - September 20, 2018 Category: Neurology Authors: Fred Stephen Sarfo, Linda Meta Mobula, Osei Sarfo-Kantanka, Sheila Adamu, Jacob Plange-Rhule, Daniel Ansong, Rexford Adu Gyamfi, James Duah, Bertha Abraham, David Ofori-Adjei Source Type: research

Estimated glomerular filtration rate predicts incident stroke among ghanaians with diabetes and hypertension
This study sought to fill this knowledge gap.
Source: Journal of the Neurological Sciences - September 20, 2018 Category: Neurology Authors: Fred Stephen Sarfo, Linda Meta Mobula, Osei Sarfo-Kantanka, Sheila Adamu, Jacob Plange-Rhule, Daniel Ansong, Rexford Adu Gyamfi, James Duah, Bertha Abraham, David Ofori-Adjei Source Type: research

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