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Role of sex hormones in modulating myocardial perfusion and coronary flow reserve
ConclusionOur experimental data in mice indicate that sex differences in myocardial perfusion are primarily driven by testosterone. Given the diagnostic importance of PET-MPI in clinical routine, further studies are warranted to determine whether testosterone levels affect the interpretation of myocardial perfusion findings in patients.
Source: European Journal of Nuclear Medicine and Molecular Imaging - January 13, 2022 Category: Nuclear Medicine Source Type: research

Hemiplegic migraine episode triggered by regadenoson
AbstractSPECT and PET myocardial perfusion imaging (MPI) are widely used to evaluate patients for coronary artery disease. Regadenoson (a selective A2A adenosine receptor agonist) is a commonly used vasodilator agent for stress MPI because of its safety profile and ease of use. Common adverse reactions such as headache, shortness of breath, flushing, and chest and abdominal discomfort are typically mild and can be effectively reversed using methylxanthines such as aminophylline and caffeine. Neurological adverse reactions such as seizure and stroke have rarely been reported with the use of regadenoson. The hemodynamic chan...
Source: Journal of Nuclear Cardiology - July 25, 2021 Category: Nuclear Medicine Source Type: research

Safety of vasodilator stress myocardial perfusion imaging in patients with elevated cardiac biomarkers
Conclusion In the setting of elevated troponin, serious complications associated with either exercise or vasodilator stress testing appear to be relatively rare with no increased risk attributable to a particular vasodilator agent.
Source: Journal of Nuclear Cardiology - February 22, 2016 Category: Nuclear Medicine Source Type: research