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Potential herb-drug interactions in community-dwelling older adults in China: the Shanghai Aging Study.
CONCLUSION: 43.3% of community-dwelling older adults who used any combination of drug-herb or herb-herb was exposed to pHDIs, and more than half of pHDIs were related to herbs with anticoagulant/antiplatelet properties. Awareness of the patterns and high-risk groups of these pHDIs may contribute to increased patient safety. PMID: 32008224 [PubMed - as supplied by publisher]
Source: Aging Clinical and Experimental Research - January 31, 2020 Category: Geriatrics Authors: Chi D, Ding D, Zhao Q, Liang X, Wu W, Luo J, Wang B Tags: Aging Clin Exp Res Source Type: research

Custom-compounded bioidentical hormone therapy: why so popular despite potential harm? The case against routine use.
Abstract Wide rejection of conventional hormone therapy (HT) after the initial publication of the Women's Health Initiative (WHI) led to unjustified use of custom-compounded bioidentical hormones. In the USA, it became an unregulated drug manufacturer industry in disguise, without proper control and making false claims and misleading advertisements. Manufacturing quality is not ensured. Unspecific harm from compounding has occurred on a large scale, such as deaths from infected products and end-stage renal failure plus carcinoma due to confusion between different Chinese herbs. Oral estrogens increase venous throm...
Source: Climacteric - May 18, 2017 Category: Geriatrics Authors: L'Hermite M Tags: Climacteric Source Type: research

Neuroprotective effects of pretreatment of ginsenoside Rb1 on severe cerebral ischemia‐induced injuries in aged mice: Involvement of anti‐oxidant signaling
ConclusionsThese observations suggest that ginsenoside Rb1 could represent promising applications as anti‐oxidants for the anti‐aging treatment of neurological disorders, such as stroke, in elderly patients. Geriatr Gerontol Int 2015; ●●: ●●–●●.
Source: Geriatrics and Gerontology International - December 29, 2015 Category: Geriatrics Authors: Xiao Dong, Lei Zheng, Shujing Lu, Yanbei Yang Tags: Original Article: Biology Source Type: research

Neuroprotective effects of pretreatment of ginsenoside Rb1 on severe cerebral ischemia ‐induced injuries in aged mice: Involvement of anti‐oxidant signaling
ConclusionsThese observations suggest that ginsenoside Rb1 could represent promising applications as anti‐oxidants for the anti‐aging treatment of neurological disorders, such as stroke, in elderly patients. Geriatr Gerontol Int 2017; 17: 338–345.
Source: Geriatrics and Gerontology International - December 28, 2015 Category: Geriatrics Authors: Xiao Dong, Lei Zheng, Shujing Lu, Yanbei Yang Tags: ORIGINAL ARTICLE: BIOLOGY Source Type: research

Effect of ninjin'yoeito, a Kampo (traditional Japanese) medicine, on cognitive impairment and depression in patients with Alzheimer's disease: 2 years of observation
ConclusionsA 2‐year follow‐up of patients receiving donepezil and NYT treatment showed an improved cognitive outcome and alleviation of AD‐related depression.
Source: Psychogeriatrics - April 27, 2015 Category: Geriatrics Authors: Chiaki Kudoh, Ryutaro Arita, Mitsuru Honda, Taichi Kishi, Yasuhiro Komatsu, Hiroaki Asou, Masaru Mimura Tags: Original Article Source Type: research