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As some hail new antibody treatment for Alzheimer ’s, safety and benefit questions persist
In a packed San Francisco conference room with a celebratory atmosphere, upbeat company representatives and scientists yesterday presented detailed clinical trial data on the first Alzheimer’s treatment shown to clearly, albeit modestly, slow the disease’s normal cognitive decline. The antibody therapy has buoyed a field marked by decades of failures. Now, it appears to be on the cusp of being greenlit by the U.S. Food and Drug Administration (FDA). Yet other researchers warn of potential risks, including brain swelling and brain hemorrhages that were linked to the recently disclosed deaths of two trial participants wh...
Source: Science of Aging Knowledge Environment - December 1, 2022 Category: Geriatrics Source Type: research

Implementation of a Transitional Care Model for Stroke: Perspectives From Frontline Clinicians, Administrators, and COMPASS-TC Implementation Staff.
DISCUSSION AND IMPLICATIONS: Multifaceted TC models are challenging to implement. Facilitators of implementation were organizational commitment and capacity, prioritizing implementation of innovative delivery models to provide comprehensive care, being able to address challenges quickly, implementing systems for tracking patients throughout the intervention, providing clinicians with autonomy and support to address challenges, and adequately resourcing the intervention. CLINICAL TRIAL REGISTRATION: NCT02588664. PMID: 32275060 [PubMed - as supplied by publisher]
Source: The Gerontologist - April 9, 2020 Category: Geriatrics Authors: Lutz BJ, Reimold AE, Coleman SW, Guzik AK, Russell LP, Radman MD, Johnson AM, Duncan PW, Bushnell CD, Rosamond WD, Gesell SB Tags: Gerontologist Source Type: research

New oral anticoagulants for prophylaxis of stroke : Results of an expert conference on practical use in geriatric patients.
PMID: 27357589 [PubMed - as supplied by publisher]
Source: Zeitschrift fur Gerontologie und Geriatrie - June 28, 2016 Category: Geriatrics Authors: Bahrmann P, Harms F, Schambeck CM, Wehling M, Flohr J Tags: Z Gerontol Geriatr Source Type: research

The Week Ahead in Brain Medicine: Stroke Studies
(MedPage Today) -- The 2014 International Stroke Conference opens Wednesday in San Diego. Also coming up this week: studies of restless legs treatment and FDA decisions on new products for hypotension and pain.
Source: MedPage Today Geriatrics - February 10, 2014 Category: Geriatrics Source Type: news