• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Trends in Lipoprotein(a) Testing at the University of Pennsylvania Health Systems from 2012-2021
Lipoprotein(a) [Lp(a)] is an independent and causal risk factor for atherosclerotic cardiovascular disease (ASCVD). Elevated Lp(a) levels are associated with a higher risk for myocardial infarction, coronary artery disease, aortic stenosis, and stroke. Lp(a) levels are primarily genetically driven and minimally impacted by diet and lifestyle, so a single measurement can identify individuals with elevated levels. However, Lp(a) screening has not been widely integrated into clinical practice in the United States.
Source: Journal of Clinical Lipidology - July 1, 2023 Category: Lipidology Authors: Archna Bajaj, Lakshmi Parvathinathan, Marjorie Risman, Ahmad Alsattari, Daniel J. Rader Tags: Best Practices in Lipid Management Source Type: research

Recommended and Observed Statin Use among U.S. Adults – National Health and Nutrition Examination Survey, 2011-2018
Heart disease and stroke are the first and fifth leading causes of death in the United States.1 A leading risk factor for both conditions, high blood cholesterol levels are positively associated with atherosclerotic cardiovascular disease (ASCVD).2-5 The 2013 American College of Cardiology/American Heart Association (ACC/AHA) Guideline on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults (2013 Cholesterol Guideline) eliminated specific LDL-c treatment targets, shifted treatment focus to use of HMG-CoA reductase inhibitors (statins), identified four patient groups most likely to bene...
Source: Journal of Clinical Lipidology - December 24, 2022 Category: Lipidology Authors: Angela M. Thompson-Paul, Cathleen Gillespie, Hilary K. Wall, Fleetwood Loustalot, Laurence Sperling, Yuling Hong Tags: Original Research Source Type: research

Triglyceride-lowering and Anti-inflammatory Mechanisms of Omega-3 Polyunsaturated Fatty Acids for Atherosclerotic Cardiovascular Risk Reduction
Atherosclerotic cardiovascular disease (ASCVD) is defined as acute coronary syndrome, stable angina, history of myocardial infarction, coronary or other arterial revascularization, ischemic stroke, transient ischemic attack, or peripheral arterial disease presumed to be of atherosclerotic origin.1 Despite continuous advances in medical intervention and surgical therapy for the treatment of ASCVD, the latter remains the leading cause of morbidity and mortality globally. In the United States, nearly 808,000 people died of ASCVD in 2014, translating to about 1 of every 3 deaths,2 and the death rate from ASCVD rose in 2015 by ...
Source: Journal of Clinical Lipidology - June 5, 2021 Category: Lipidology Authors: Qiyuan Keith Liu Tags: Review Article Source Type: research

Case Report: 68 yo Chinese-American woman with high HDL-C and ischemic stroke attributed to intracranial atherosclerotic stenosis
Atherosclerotic cardiovascular disease (ASCVD) events are the most common cause of death in the United States and for most individuals who experience these events, may be predicted by risk identification tools. ASCVD risk calculators enable a clinician-patient discussion and the presence of risk-enhancing factors may further inform decision-making with respect to preventive pharmacotherapy, especially statin prescription. In cases where the decision of whether to treat with medicine is unclear, coronary artery calcium scoring by computed tomography offers enhanced risk stratification and may allow both clinicians and patie...
Source: Journal of Clinical Lipidology - January 27, 2021 Category: Lipidology Authors: Jan Gong, Stephanie Byers Asher, Brett Cucchiara, Marina Cuchel, Daniel Soffer Tags: Case Report Source Type: research