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A cohort study on risk factors of high-density lipoprotein cholesterol hypolipidemia among urban Chinese adults
High-density lipoprotein cholesterol (HDL-C) hypolipidemia, a major type of dyslipidemia, has been associated with many kinds of diseases, such as stroke, coronary heart disease, obesity and diabetes, and has ...
Source: Lipids in Health and Disease - February 22, 2021 Category: Lipidology Authors: Fang Tang, Jian Wang, Stephen Nicholas, Dongfu Qian and Rugang Liu Tags: Research Source Type: research

Adiponectin, lipids and atherosclerosis
Purpose of review: Adiponectin is an adipokine with anti-inflammatory, antioxidant, antiatherogenic, pro-angiogenic, vasoprotective and insulin-sensitizing properties. Several factors may influence adiponectin levels, such as genetic polymorphisms, obesity / body fat distribution, diet and exercise as well as cardiovascular risk factors such as sleep deprivation and smoking as well as medications. Adiponectin has been proposed as a potential prognostic biomarker and a therapeutic target in patients with cardiometabolic diseases. Recent findings: This narrative review discusses the associations of adiponectin with obesity-...
Source: Current Opinion in Lipidology - July 14, 2017 Category: Lipidology Tags: HYPERLIPIDAEMIA AND CARDIOVASCULAR DISEASE: Edited by Paul N. Durrington Source Type: research

Sphingolipids in cardiovascular diseases and metabolic disorders
Many investigations suggest the pivotal role of sphingolipids in the pathogenesis of lifestyle diseases such as myocardial infarction, hypertension, stroke, diabetes mellitus type 2 and obesity. Some studies suggest that sphingolipids are important factors in cellular signal transduction. They serve as biologically active components of cell membrane and are involved in many processes such as proliferation, maturation and apoptosis. Recently, ceramide and sphingosine-1-phomsphate has become the target of many investigations. Ceramide is generated in three metabolic pathways and many factors induce its production as a cellul...
Source: Lipids in Health and Disease - June 16, 2015 Category: Lipidology Authors: Sonia BorodziczKatarzyna CzarzastaMarek KuchAgnieszka Cudnoch-Jedrzejewska Source Type: research

From the Editor: What is obesity?
The concern about the prevalence of obesity in the population of the United States (now around the world) has grown as our epidemiologic colleagues have pointed out the associated disease states such as dyslipidemia, high blood pressure, diabetes, myocardial infarction, and stroke. We now recognize it to be a disease entity unto itself with causative elements in both genetic and environmental realms. There seems to be general agreement that this disease is linked to an increase in adipose tissue generally but with issues of enhanced effect when the excess fat cells are located within the abdominal cavity or when there is a...
Source: Journal of Clinical Lipidology - June 5, 2013 Category: Lipidology Authors: W. Virgil Brown Tags: Foreword Source Type: research

Impact of Obesity and Healthy Eating Index on Coronary Heart Disease, Stroke, and Cardiovascular Disease Mortality in United States Adults*
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Source: Journal of Clinical Lipidology - May 1, 2013 Category: Lipidology Authors: Rohini J. Patel, Geeta Sikand, Christopher Patao, Nathan Wong Tags: Abstracts Source Type: research

Influence of obesity and cardiometabolic makers on lipoprotein-associated phospholipase A2 (Lp-PLA2) activity in adolescents: the healthy young cross-sectional study
Background: Lipoprotein-associated phospholipase A2 activity (Lp-PLA2) is a good marker of cardiovascular risk in adults. It is strongly associated with stroke and many others cardiovascular events. Despite this, the impact of obesity on this enzyme activity and its relation to biomarkers of cardiovascular disease in adolescents is not very well investigated. The purpose of this article is evaluates the influence of obesity and cardiometabolic markers on Lp-PLA2 activity in adolescents. Results: This cross-sectional study included 242 adolescents (10--19 years) of both gender. These subjects were classified in Healthy Weig...
Source: Lipids in Health and Disease - February 15, 2013 Category: Lipidology Authors: Isis da SilvaAnelise TimmNágila Damasceno Source Type: research