Filtered By:
Specialty: Neurosurgery
Source: Clinical Neurology and Neurosurgery
This page shows you your search results in order of date.
Order by Relevance | Date
Total 149 results found since Jan 2013.
Acceleration of blood flow as an indicator of improved hemodynamics after indirect bypass surgery in Moyamoya disease
Moyamoya disease is characterized by a steno-occlusive lesion in the distal internal carotid artery, with development of a range of collateral networks. Long-term hemodynamic overstress in Moyamoya disease can induce pathological changes in the dilated collateral vessels, including the lenticulostriate arteries, choroidal arteries, and other basal vessels [1 –3]. The development of collateral vessels can increase the risk of rupture, which leads to hemorrhagic stroke. This hemodynamic stress is relieved by bypass flow surgery, which reduces the burden on the Moyamoya vessels to maintain cerebral blood flow.
Source: Clinical Neurology and Neurosurgery - June 26, 2017 Category: Neurosurgery Authors: Sayaka Ogawa, Toshiyasu Ogata, Hirofumi Shimada, Hiroshi Abe, Toshiro Katsuta, Kenji Fukuda, Tooru Inoue Source Type: research
Serum lipoprotein-associated phospholipase A2 predicts the formation of carotid artery plaque and its vulnerability in anterior circulation cerebral infarction
Stroke is the leading cause of adult death and disability in China. Vulnerability of the atherosclerotic plaque is one of the pathological processes of ischemic stroke [1,2]. Recent researches demonstrate that inflammation plays an important role in atherosclerosis [3 –5] and inflammatory markers reveal the subclinical changes of stroke [6,7]. Evidence has been provided that high-sensitive C-creative protein (hsCRP) and lipoprotein-associated phospholipase A2 (Lp-PLA2) show prognostic value in stroke and coronary heart disease [8–12].
Source: Clinical Neurology and Neurosurgery - June 14, 2017 Category: Neurosurgery Authors: Yuping Yang, Tao Xue, Juehua Zhu, Jiayi Xu, Xiaowei Hu, Penghao Wang, Tao Kong, Yan Yan, Lihui Yang, Shouru Xue Source Type: research
Etiologic classification of ischemic stroke: where do we stand?
Stroke is nowadays one of the major global health problems, comprising 75.2% of deaths and 81.0% of stroke-related disability adjusted life years lost in developing countries [1]. Up to 87% of the global burden of stroke is attributed to ischemic stroke, which is a heterogeneous disorder with more than 100 pathologies implicated in its pathogenesis [2]. Therefore, a reliable and precise etiologic classification of this disease is highly important for both daily clinical practice and research purposes [3 –5].
Source: Clinical Neurology and Neurosurgery - May 23, 2017 Category: Neurosurgery Authors: R ăzvan Alexandru Radu, Elena Oana Terecoasă, Ovidiu Alexandru Băjenaru, Cristina Tiu Source Type: research
CT and MRI-based Door-Needle-Times for acute stroke patients A quasi-randomized clinical trial
The aim of this study was to compare DNT for CT versus MRI-based acute stroke-evaluation.
Source: Clinical Neurology and Neurosurgery - May 10, 2017 Category: Neurosurgery Authors: Christine Krarup Hansen, Anders Christensen, Helen Rodgers, Inger Havsteen, Christina Kruuse, Janus Nybing, Mari-Anne Kaasb øl, Hanne Christensen Source Type: research
Development of a prognostic scale for severely hemiplegic stroke patients in a rehabilitation hospital
There are many goals involved with stroke rehabilitation. The main goals are: (1) the ability to walk; (2) to improve the activities of daily living (ADL); and (3) to return home after recovery. To date, different scales have been proposed in stroke rehabilitation for the prediction of the prognosis in terms of the ability to walk [1 –3], ability to carry out ADL [4–6], duration of hospital stay [7–9], and destination [10]. However, most of these methods are aimed at predicting a single goal, and as a result, they allowed for the extraction of factors that are important for the prognosis of the concerned goals, but d...
Source: Clinical Neurology and Neurosurgery - April 28, 2017 Category: Neurosurgery Authors: Yoshitake Hirano, Osamu Nitta, Takeshi Hayashi, Hidetoshi Takahashi, Yasuhiro Miyazaki, Hiroshi Kigawa Source Type: research
Endothelin Polymorphisms as a Risk Factor for Cerebral Aneurysm Rebleeding Following Aneurysmal Subarachnoid Hemorrhage
Aneurysmal subarachnoid hemorrhage (aSAH) represents a unique form of hemorrhagic stroke due to rupture of an intradural cerebral aneurysm and is associated with high rates of morbidity and mortality. Considerable variation in the annual incidence of aSAH exists among different regions of the world with an incidence ranging from 2 to 16 cases per 100,000 [1,2]. Following the diagnosis of aSAH, early surgical or endovascular treatment of the aneurysm is recommended to reduce the rate of aneurysm rerupture [2].
Source: Clinical Neurology and Neurosurgery - April 7, 2017 Category: Neurosurgery Authors: Paul M. Foreman, Robert M. Starke, Philipp Hendrix, Mark R. Harrigan, Winfield S. Fisher, Nilesh A. Vyas, Robert H. Lipsky, Minkuan Lin, Beverly C. Walters, Jean-Francois Pittet, Mali Mathru, Christoph J. Griessenauer Source Type: research
Correlation between cervical artery kinking and white matter lesions
White matter lesions (WMLs), commonly called cerebral white matter hyperintensity or leukoaraiosis, are manifestations of cerebral small vessel disease [1]. Furthermore, WMLs include periventricular white matter hyperintensity (PVWMH) and deep white matter hyperintensity (DWMH). The incidence of WMLs in the elderly population is approximately 20%, which is significantly higher than the incidence reported in young people [2]. Moreover, it is widely regarded to be associated with stroke, dementia, and a high risk of death [3].
Source: Clinical Neurology and Neurosurgery - April 3, 2017 Category: Neurosurgery Authors: Liang Yin, Qianqian Li, Lina Zhang, Weidong Qian, Xiaolin Liu Source Type: research
Vascular closure devices in stroke patients receiving tissue plasminogen activator: A retrospective analysis from an academic tertiary medical center and a teaching community hospital stroke database
Stroke is the fourth leading cause of death in the United States [1]. Recanalization, or opening, of the blocked artery in ischemic stroke patients can limit the extent of infarction and significantly improve a patient's outcome [2]. In 1995, NINDS tPA (tissue plasminogen activator) trial suggested that tPA administered intravenously within three hours of stroke onset could improve functional outcomes in patients [3]. Since then, acute stroke therapy has been in constant evolution with the universal goals of improving outcomes and reduction in complications.
Source: Clinical Neurology and Neurosurgery - March 29, 2017 Category: Neurosurgery Authors: Mangaladevi S. Patil, Mahesh V. Jayaraman, Sun H. Ahn Source Type: research
Number needed to treat for stroke thrombectomy based on a systematic review and meta-analysis
Ischemic stroke is a major cause of death worldwide, which has defied treatment efforts well into the era of modern medicine [1]. Beginning in the 1990s, the NINDS rt-PA trial revolutionized medical management of acute ischemic stroke, demonstrating that rt-PA started within 3hours of symptoms results in improved outcomes at 90days (OR 1.7 [1.2 –2.6]) [2]. Three years later, the ECASS III trial showed similar results for rt-PA given within 4.5hours [3]. The number needed to treat (NNT) for rt-PA administered with 4.5hours is between 4 and 13 [4].
Source: Clinical Neurology and Neurosurgery - March 9, 2017 Category: Neurosurgery Authors: Ephraim W. Church, Alexandra Gundersen, Michael J. Glantz, Scott D. Simon Tags: Review Source Type: research
Addendum to ‘Occurrence and recurrence of spontaneous chronic subdural haematoma is associated with a factor XIII deficiency’ Clin. Neurol. Neurosurg. 115 (January (1)) (2013) 13–18
The authors regret Keywords: Chronic subdural haematoma; Factor XIII; (Spontaneous) Chronic subdural haematoma; Haemostatic disorders; Differential diagnosis of stroke; Blood vessels; Wound healing.
Source: Clinical Neurology and Neurosurgery - February 23, 2017 Category: Neurosurgery Authors: Bert Bosche, Marek Molcanyi, Thomas Noll, Matthias Kochanek, Bastian Kraus, Bernhard Rieger, Faycal El Majdoub, Christian Dohmen, Mario L öhr, Roland Goldbrunner, Gerrit Brinker Tags: Addendum Source Type: research
Hereditary cerebral small vessel disease and stroke
Hereditary small vessel diseases are a minor part of cerebral small vessel disease (SVD), which is known to cause ischemic and hemorrhagic strokes and dementia [1]. About 25% of ischemic strokes are attributed to small vessel disease [2].
Source: Clinical Neurology and Neurosurgery - February 22, 2017 Category: Neurosurgery Authors: Christian Baastrup S øndergaard, Jørgen Erik Nielsen, Christine Krarup Hansen, Hanne Christensen Tags: Review Article Source Type: research
Hereditary Cerebral Small Vessel Disease
and Stroke
Hereditary small vessel diseases are a minor part of cerebral small vessel disease (SVD), which is known to cause ischemic and hemorrhagic strokes and dementia [1]. About 25% of ischemic strokes are attributed to small vessel disease [2].
Source: Clinical Neurology and Neurosurgery - February 22, 2017 Category: Neurosurgery Authors: Christian Baastrup S øndergaard, Christine Krarup Hansen, Hanne Christensen, Jørgen Erik Nielsen Tags: Review Article Source Type: research
An individualized Coaching Program for patients with Acute Ischemic Stroke: feasibility study
Stroke mortality has been declining over the past decades, partially by reduced incidence of stroke and lower case-fatality rates [1]. These significant improvements are partially related to the improved cardiovascular risk factor control interventions on arterial hypertension, diabetes mellitus and dyslipidemia control, and smoking cessation programs [2]. Despite evidence-based guidelines, these therapeutic strategies recommended for secondary prevention are rather modestly implemented. Significant deficiencies in secondary prevention care in the real world have been reported [3].
Source: Clinical Neurology and Neurosurgery - January 23, 2017 Category: Neurosurgery Authors: P. Vanacker, D. Standaert, N. Libbrecht, I. Vansteenkiste, D. Bernard, L. Yperzeele, G. Vanhooren Source Type: research
Timing of Anticoagulant Re-Initiation following Intracerebral Hemorrhage in Mechanical Heart Valves: Survey of Neurosurgeons and Thrombosis Experts
While oral anticoagulation is universally recommended among patients with mechanical heart valves (MHVs) [1], there is limited evidence to guide clinicians in managing patients who suffer intracerebral hemorrhage (ICH), a feared complication of anticoagulant treatment estimated to occur at 2-3% per patient-year [2]. In particular, the timing of oral anticoagulant (OAC) re-initiation following stabilization of hemorrhage is challenged by the intricate need to balance the risks of valve thrombosis and ischemic stroke with those of recurrent bleeding.
Source: Clinical Neurology and Neurosurgery - January 13, 2017 Category: Neurosurgery Authors: Fahad AlKherayf, Yan Xu, Harrison Westwick, Ioana Doina Moldovan, Philip S. Wells Source Type: research
Thrombolytic Treatment to Stroke Mimic Patients via Telestroke
The safety of intravenous thrombolysis (IVT) use among patients presenting with conditions mimicking acute ischemic stroke (AIS) is well established [1]. Rates of patients with stroke mimics (SM) treated with IVT at community hospitals who follow a “drip-and-ship” paradigm is higher than rates found for those presenting to stroke centers [2]. The implementation of telestroke (TS) where neurologists are connected to hospitals in areas without on-site neurological expertise has been proven to be effective in the safe implementation of IVT [3 ].
Source: Clinical Neurology and Neurosurgery - December 13, 2016 Category: Neurosurgery Authors: Ganesh Asaithambi, Amy L. Castle, Michael A. Sperl, Jayashree Ravichandran, Aditi Gupta, Bridget M. Ho, Sandra K. Hanson Source Type: research
