Serum lipoprotein-associated phospholipase A2 predicts the formation of carotid artery plaque and its vulnerability in anterior circulation cerebral infarction

Stroke is the leading cause of adult death and disability in China. Vulnerability of the atherosclerotic plaque is one of the pathological processes of ischemic stroke [1,2]. Recent researches demonstrate that inflammation plays an important role in atherosclerosis [3 –5] and inflammatory markers reveal the subclinical changes of stroke [6,7]. Evidence has been provided that high-sensitive C-creative protein (hsCRP) and lipoprotein-associated phospholipase A2 (Lp-PLA2) show prognostic value in stroke and coronary heart disease [8–12].
Source: Clinical Neurology and Neurosurgery - Category: Neurosurgery Authors: Source Type: research