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Specialty: Child Development

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Total 143 results found since Jan 2013.

Basilar artery strokes in children: good outcomes with conservative medical treatment
AimTo describe outcomes and outcome predictors in childhood basilar artery stroke (BAS). MethodWe prospectively enrolled children with BAS with or without basilar artery occlusion (BAO) in the Toronto Children's Stroke Registry from 1992 to 2009. We assessed presenting features and outcomes including Pediatric Stroke Outcome Measure scores. ResultsAmong 578 children with acute arterial ischemic stroke, 27 had BAS (4.6% including neonates, 6% excluding neonates). Twenty‐four (14 males, 10 females) children met study criteria (mean age at stroke was 8y 10mo; range 0–17y). Eleven children had BAO. Aspirin or anticoagulati...
Source: Developmental Medicine and Child Neurology - February 17, 2013 Category: Child Development Authors: Ana Marissa Lagman‐Bartolome, Ann‐Marie Pontigon, Mahendranath Moharir, Daune L. Macgregor, Rand Askalan, Ivanna Yau, Gabrielle Deveber Tags: Original Article Source Type: research

Should paediatric stroke be treated as adult stroke?
This commentary is on the original article by Lagman‐Bartolome et al
Source: Developmental Medicine and Child Neurology - February 11, 2013 Category: Child Development Authors: Manoëlle Kossorotoff Tags: Commentary Source Type: research

The epidemiology of intermittent and chronic ataxia in children in Manitoba, Canada
AimTo determine the epidemiology of chronic ataxia in children in Manitoba, Canada. MethodA retrospective study using multiple sources and disease codes identified children (age 0–16y) with chronic ataxia (>2mo duration or recurrent episodes of ataxia) seen at Winnipeg Children's Hospital from 1991 to 2008. Patients with isolated peripheral nerve diseases, vestibular disorders, or brain tumors were excluded. ResultsWe identified 184 patients (males=females; mean age 15y, SD 7y 8mo) with chronic ataxia. Median age at the presenting symptom onset was 1 year 3 months and at ataxia onset 3 years 1 month. Median durati...
Source: Developmental Medicine and Child Neurology - February 7, 2013 Category: Child Development Authors: Michael S Salman, Esther J Lee, Anindita Tjahjadi, Bernard N Chodirker Tags: Original Article Source Type: research

Neonatal posterior cerebral artery stroke: clinical presentation, MRI findings, and outcome
AimTo report the clinical presentation, magnetic resonance imaging (MRI) findings, and follow‐up data of newborn infants with perinatal arterial ischemic stroke in the territory of the posterior cerebral artery (PCA). MethodData on 18 newborn infants from three neonatal intensive care units (11 males, seven females) with an MRI‐confirmed PCA stroke were analysed and reported. Infants were born at a mean gestational age of 38.7 weeks (SD 3.4) with a mean birthweight of 3244g (SD 850). ResultsFourteen infants presented with clinical seizures. Five of these had associated hypoxic–ischemic encephalopathy, four had hypog...
Source: Developmental Medicine and Child Neurology - January 22, 2013 Category: Child Development Authors: Niek E Aa, Jeroen Dudink, Manon J N L Benders, Paul Govaert, Henrica L M Straaten, Giorgio L Porro, Floris Groenendaal, Linda S Vries Tags: Original Article Source Type: research

Neonatal arterial ischemic stroke: it's not just about motor and cognitive outcome
This commentary is on the original article by van der Aa et al.
Source: Developmental Medicine and Child Neurology - January 22, 2013 Category: Child Development Authors: Mahendranath Moharir Tags: Commentary Source Type: research

Reproducibility of two functional field exercise tests for children with cerebral palsy who self‐propel a manual wheelchair
AimThe aim of this study was to examine the test–retest reproducibility (reliability and agreement) of the 6‐minute push test (6MPT) and the one‐stroke push test (1SPT), and construct validity of the 6MPT in children with cerebral palsy (CP) who self‐propel a manual wheelchair. MethodSeventy‐three children and adolescents with spastic CP (51 males, 22 females; mean age 11y 9mo, SD 3y 7mo, range 4–18y; three unilateral, 70 bilateral) using a manual wheelchair for at least part of the day were recruited from and tested in different rehabilitation settings in the Netherlands and Brazil. Participants were classifie...
Source: Developmental Medicine and Child Neurology - December 18, 2012 Category: Child Development Authors: Olaf Verschuren, Marjolijn Ketelaar, Janke De Groot, FÁbio Vila Nova, Tim Takken Tags: Original Article Source Type: research

How commonly do children with complex cerebral arteriopathy have renovascular disease?
AimTo describe the frequency of renovascular abnormalities and hypertension in an opportunistic cohort of children with complex cerebrovascular disease from a single tertiary/quaternary referral centre. MethodThis was a retrospective case note and imaging review of children who had had cerebral and renal angiography, with a diagnosis of moyamoya or other occlusive cerebrovascular disease (OCVD). Hypertension was defined as at least three systolic blood pressure readings of the 95th centile or above. ResultsOf 34 children (12 males, 22 females; median age 5y 11mo, range 2mo‐15y 3mo; 20 with moyamoya, 14 with OCVD), primar...
Source: Developmental Medicine and Child Neurology - December 18, 2012 Category: Child Development Authors: Alex Willsher, Derek J Roebuck, Joanne Ng, Vijeya Ganesan Tags: Original Article Source Type: research

Association between radiographic Wallerian degeneration and neuropathological changes post childhood stroke
Aim  Wallerian degeneration is a radiological finding thought to reflect corticospinal tract degeneration. This finding on magnetic resonance imaging (MRI) is routinely used as a predictor of poor prognosis in childhood stroke. However, its validity has never been established. Our objective was to correlate Wallerian degeneration seen on MRI with histopathology. Method  We searched the databases of the Department of Pathology and Children’s Stroke registry at the Hospital for Sick Children, Toronto for autopsy specimens exhibiting focal infarcts from children born at term who underwent MRI after a stroke. The specime...
Source: Developmental Medicine and Child Neurology - November 22, 2012 Category: Child Development Authors: KEVIN C JONES, CYNTHIA HAWKINS, DEREK ARMSTRONG, GABRIELLE DEVEBER, DAUNE MACGREGOR, MAHENDRANATH MOHARIR, RAND ASKALAN Tags: ORIGINAL ARTICLE Source Type: research