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A Serious Diagnosis Lacking Common Symptoms
​BY JENNIFER TUONG; IVAN KHARCHENKO; JEAN LUC AGARD; & AHMED RAZIUDDIN, MDA 65-year-old man who had HIV well-controlled with highly active antiretroviral therapy, hypertension, sciatica, and restless leg syndrome presented to the emergency department with left leg pain. He also had had chemotherapy and radiation for anal cancer. The patient said the pain had started 45 minutes earlier when he was sitting on the toilet.He described the pain as sore in quality and 10/10 on the pain scale. He reported that it had started in his lower back and radiated to his left leg. He said he had had no trauma or weakness to the regi...
Source: The Case Files - May 28, 2019 Category: Emergency Medicine Tags: Blog Posts Source Type: research

Stroke Dysbiosis Index (SDI) in Gut Microbiome Are Associated With Brain Injury and Prognosis of Stroke
Conclusions: We developed an index to measure gut microbiota dysbiosis in stroke patients; this index was significantly correlated with patients' outcome and was causally related to outcome in a mouse model of stroke. Our model facilitates the potential clinical application of gut microbiota data in stroke and adds quantitative evidence linking the gut microbiota to stroke. Introduction Ischemic stroke imposes a heavy burden on society, with 24.9 million cases worldwide (1). Although intravenous thrombolysis and endovascular treatment greatly improve some patients' prognosis, the prognosis for most pa...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

Quantifying Cerebral Collaterals In Carotid Artery Dissection May Help Stratify Stroke Risk. (P3.110)
CONCLUSIONS: These uncontrolled data suggest that a quantified score of distal cerebral collaterals could help stratify stroke risk and help guide management in patients with carotid artery dissection. Further controlled, prospective study in a larger and more diverse sample is warranted.Study Supported by: AHA/ASA NCRP 13CRP14140001Disclosure: Dr. Southerland has received personal compensation in an editorial capacity for Neurology Podcast. Dr. Gaughen has received personal compensation for activities with Covidien Neurovascular, Microvention, and Stryker Neurovascular as a consultant. Dr. McMurry has nothing to disclose....
Source: Neurology - April 9, 2014 Category: Neurology Authors: Southerland, A., Gaughen, J., McMurry, T., Wintermark, M., Majersik, J., Worrall, B. Tags: Cerebrovascular Disease and Interventional Neurology: Large Vessel Nonatherosclerotic Arteriopathies Source Type: research