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Platelets at the Vessel Wall in Non-Thrombotic Disease
Circ Res. 2023 Mar 17;132(6):775-790. doi: 10.1161/CIRCRESAHA.122.321566. Epub 2023 Mar 16.ABSTRACTPlatelets are small, anucleate entities that bud from megakaryocytes in the bone marrow. Among circulating cells, platelets are the most abundant cell, traditionally involved in regulating the balance between thrombosis (the terminal event of platelet activation) and hemostasis (a protective response to tissue injury). Although platelets lack the precise cellular control offered by nucleate cells, they are in fact very dynamic cells, enriched in preformed RNA that allows them the capability of de novo protein synthesis which ...
Source: Circulation Research - March 17, 2023 Category: Cardiology Authors: Anu Aggarwal Courtney L Jennings Emily Manning Scott J Cameron Source Type: research
