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Lower Extremity Proximal Muscle Function and Dyspnea in Older Persons
ConclusionPoor performance on a single chair stand was associated with an adjusted 85% greater likelihood of moderate to severe exertional dyspnea than normal performance. These results suggest that reduced proximal muscle function of the lower extremities is associated with moderate to severe exertional dyspnea, even after adjusting for multiple confounders.
Source: Journal of the American Geriatrics Society - July 22, 2015 Category: Geriatrics Authors: Carlos A. Vaz Fragoso, Katy Araujo, Linda Leo‐Summers, Peter H. Van Ness Tags: Brief Reports Source Type: research

Cognitive dysfunction is greater in patients hospitalised with COPD exacerbations than with worsening heart failure
ConclusionsHospitalised COPD patients with exacerbations have greater cognitive impairment than those with worsening heart failure. Differences may be explained by greater smoking load and more anxiety and depression.
Source: European Respiratory Journal - December 23, 2014 Category: Respiratory Medicine Authors: Bajaj, M., Tappouni, A., Tumilty, M., Dodd, J., Jones, P., Baker, E. Tags: 1.12 Clinical Problems - COPD Source Type: research

Assessment of Risk in Chronic Airways Disease Evaluation (ARCADE): Protocol and preliminary data.
Abstract Chronic obstructive pulmonary disease (COPD) is a multisystem disease. Established comorbidities include cardiovascular disease, osteoporosis, loss of muscle mass and function, depression, and impaired quality of life. The natural history is not well understood. The Assessment of Risk in Chronic Airways Disease Evaluation (ARCADE) is a longitudinal study of comorbidities in COPD. The primary aims are to delineate the progression and interrelationships of cardiovascular disease and associated comorbidities. Each year ARCADE aims to recruit 250 patients diagnosed with COPD and 50 comparators (free from resp...
Source: Chronic Respiratory Disease - August 26, 2014 Category: Respiratory Medicine Authors: Gale NS, Albarrati AM, Munnery MM, Munnery IC, Irfan M, Bolton CE, Rambaran CN, Singer RM, Cockcroft JR, Shale DJ Tags: Chron Respir Dis Source Type: research