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Hemophagocytic lymphohistiocytosis diagnosed by bone marrow trephine biopsy in living post-COVID-19 patients: case report and mini-review
AbstractHemophagocytic lymphohistiocytosis (HLH) constitutes a life-threatening inflammatory syndrome. Postmortem histological findings of bone marrow (BM) from COVID-19 patients showed histiocytosis and hemophagocytosis and supported the hypothesis that secondary HLH (sHLH) may be triggered by SARS-CoV-2 infection. However, there are a limited number of sHLH cases in which trephine has been performed in living post-COVID-19 patients. Here we present a recent case and a mini-review of sHLH diagnosed by trephine biopsy in living patients after COVID-19. An 81-year-old man with a past medical history of hypertension, diabete...
Source: Journal of Molecular Histology - June 14, 2022 Category: Laboratory Medicine Source Type: research

Reducing Laboratory Turnaround Time in Patients With Acute Stroke and the Lack of Impact on Time to Reperfusion Therapy
CONCLUSIONS.—: The new laboratory workflow significantly decreased transportation time, TAT of individual tests, and the blood drawn-to-laboratory reported time. However, the time to treatment of acute ischemic stroke patients was not different between preimplementation and postimplementation.PMID:35486488 | DOI:10.5858/arpa.2021-0444-OA
Source: Archives of Pathology and Laboratory Medicine - April 29, 2022 Category: Laboratory Medicine Authors: Sasipong Trongnit Kanit Reesukumal Gerald J Kost Yongchai Nilanont Busadee Pratumvinit Source Type: research