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Clearance of serum solutes by hemofiltration in dogs with severe heat stroke
Background: We have previously reported that hemofiltration (HF) may be an effective additional means of treating heat stroke when rapid cooling is not effective. Methods: Dogs were assigned to a heat stroke (control) or heat stroke?+?hemofiltration (HF) group (n?=?8 each group). After heat stroke induction, dogs in the HF group received HF for 3?h. Serum concentrations of interleukin (IL)-10, tumor necrosis factor (TNF)-?, IL-6, blood urea nitrogen (BUN) and creatinine were measured at baseline and 1, 2, and 3?h after heat stroke. Clearance rates of solutes were determined 1, 2, and 3?h after the start of HF. Results: Ser...
Source: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine - August 22, 2014 Category: Emergency Medicine Authors: Guang-Ming ChenYu-Ying LanCheng-Feng WangHai-Xia ZhanWen-Rui WangJin-Hua ChenJian Chen Source Type: research

Clearance of myoglobin by high cutoff continuous veno‐venous hemodialysis in a patient with rhabdomyolysis: A case report
Abstract Continuous veno‐venous hemodialysis using high cutoff filters (HCO‐CVVHD) is a promising technique, which may be effective to decrease the extremely high level of circulating myoglobin in patients with rhabdomyolysis (RM). Here, we report a patient with RM caused by heat stroke who was successfully treated by HCO‐CVVHD. A male patient received HCO‐CVVHD with 4 L/h dialysate for 5 days and then pre‐dilution continuous veno‐venous hemofiltration (CVVH) at a dose of 4 L/h until recovery of renal function. The clearance of myoglobin and albumin at 5 minutes, and at 4, 12, and 24 hours were calculated. ...
Source: Hemodialysis International - April 27, 2014 Category: Hematology Authors: Bunyun Wu, Dehua Gong, Daxi Ji, Bin Xu, Zhihong Liu Tags: Case Report Source Type: research