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Trends, Predictors, and Outcomes of Stroke After Surgical Aortic Valve Replacement in the United States.
CONCLUSIONS: The incidence of stroke after AVR has decreased but remains a significant cause of morbidity in medium- and high-risk patients. Superior outcomes can be achieved in medium- to high-risk patients at high-volume centers. PMID: 26611821 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - November 20, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Idrees JJ, Schiltz NK, Johnston DR, Mick S, Smedira NG, Sabik JF, Blackstone EH, Svensson LG, Soltesz EG Tags: Ann Thorac Surg Source Type: research

Development and Application of a Risk Prediction Model for In-Hospital Stroke After Transcatheter Aortic Valve Replacement - A Report from the Society of Thoracic Surgeons/American College of Cardiology Transcatheter Valve Therapy Registry.
CONCLUSIONS: A risk model for in-hospital stroke following TAVR was developed from the STS/ACC TVT Registry and used to estimate site-specific stroke performance. This model can serve as a valuable resource for quality improvement, clinical decision-making, and patient counseling. PMID: 30529671 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - December 7, 2018 Category: Cardiovascular & Thoracic Surgery Authors: Thourani VH, O'Brien SM, Kelly JJ, Cohen DJ, Peterson ED, Mack MJ, Shahian DM, Grover FL, Carroll EJ, Brennan JM, Forcillo J, Arnold SV, Vemulapalli S, Fitzgerald S, Holmes DR, Bavaria JE, Edwards FH Tags: Ann Thorac Surg Source Type: research

In DeBakey Type I Aortic Dissection, Bovine Aortic Arch Is Associated With Arch Tears and Stroke.
CONCLUSIONS: BAA is an independent predictor for the distinctive location of the entry site in the aortic arch and risk factor for stroke. PMID: 28811002 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - August 12, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Dumfarth J, Peterss S, Kofler M, Plaikner M, Ziganshin BA, Schachner T, Tranquilli M, Grimm M, Elefteriades JA Tags: Ann Thorac Surg Source Type: research

Endoaortic Clamping Does Not Increase the Risk of Stroke in Minimal Access Mitral Valve Surgery: A Multicenter Experience.
CONCLUSIONS: Once procedural proficiency is acquired, endoaortic balloon clamping in MIMVS is a safe and effective technique. Despite the fact that this patient cohort also includes combined and redo procedures, the observed mortality and stroke rate compared favorably with the existing literature on primary isolated mitral valve surgery irrespective of the approach. PMID: 26163356 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - July 7, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Casselman F, Aramendi J, Bentala M, Candolfi P, Coppoolse R, Gersak B, Greco E, Herijgers P, Hunter S, Krakor R, Rinaldi M, Van Praet F, Van Vaerenbergh G, Zacharias J Tags: Ann Thorac Surg Source Type: research

Impact of Perioperative Stroke on Mid Term Outcomes after Transcatheter Aortic Valve Replacement.
CONCLUSIONS: Stroke increases short term and mid-term mortality following TAVR. Risk prediction for neurologic events in TAVR could aid framework for patient selection, further improving outcomes. PMID: 32151578 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - March 5, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Habertheuer A, Gleason TG, Kilic A, Schindler J, Kliner D, Bianco V, Toma C, Aranda-Michel E, Kacin A, Sultan I Tags: Ann Thorac Surg Source Type: research

Institutional Variation in Mortality After Stroke After Cardiac Surgery: An Opportunity for Improvement.
CONCLUSIONS: Institutional variation, more so than individual patient risk factors, is highly associated with postoperative stroke and FTR rates after stroke after cardiac surgery. Postoperative stroke remains significantly associated with mortality and morbidity. Institutional practice patterns may confer a disproportionate influence on postoperative stroke independent of case mix. Understanding differences between high and low performing centers is essential to improving outcomes, costs, and hospital quality. PMID: 26188969 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - July 15, 2015 Category: Cardiovascular & Thoracic Surgery Authors: LaPar DJ, Quader M, Rich JB, Kron IL, Crosby IK, Kern JA, Tribble CG, Speir AM, Ailawadi G Tags: Ann Thorac Surg Source Type: research

Valve-Sparing Root Replacement vs Composite Valve Grafting in Aortic Root Dilation: A Meta-Analysis.
CONCLUSIONS: Aortic valve sparing appears to be safe, and associated with reduced late mortality, thromboembolism/stroke and bleeding compared with composite valve grafting. Late durability is equivalent. Aortic valve sparing should be considered in patients with favorable aortic valve morphology. PMID: 31981499 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - January 21, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Elbatarny M, Tam DY, Edelman JJ, Rocha RV, Chu MWA, Peterson MD, El-Hamamsy I, Appoo JJ, Friedrich JO, Boodhwani M, Yanagawa B, Ouzounian M, Canadian Thoracic Aortic Collaborative (CTAC) Investigators Tags: Ann Thorac Surg Source Type: research

Less-Invasive Aortic Valve Replacement: Trends and Outcomes from the STS Database.
CONCLUSIONS: LI-AVR is associated with a similar operative mortality and postoperative stroke rate compared to FS. LI-AVRS should be served as a benchmark for comparison between TAVR and sAVR in low risk patients. PMID: 32835750 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - August 20, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Ghoreishi M, Thourani VH, Badhwar V, Massad M, Svensson L, Taylor BS, Pasrija C, Gammie JS, Jacobs JP, Cox M, Grau-Sepulveda M, Brennan M, Griffith BP, Milliken JC, Abdelhady K, Kon Z Tags: Ann Thorac Surg Source Type: research

Outcomes of current generation Transfemoral Balloon-Expandable versus Self-Expandable TAVR.
CONCLUSIONS: Mid-term outcomes of both valve types were comparable despite a higher risk of short term stroke for the SE cohort. Select patients may benefit from one valve type over another based on clinical and anatomic risk factors. PMID: 33045207 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - October 9, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Habertheuer A, Gleason TG, Kilic A, Schindler J, Kliner D, Bianco V, Aranda-Michel E, Brown JA, Toma C, Muluktula S, Sultan I Tags: Ann Thorac Surg Source Type: research

Transapical Aortic Valve Replacement for Severe Aortic Stenosis: Results From the Nonrandomized Continued Access Cohort of the PARTNER Trial.
CONCLUSIONS: Among the 975 patients in the NRCA-TA cohort, rates of major outcomes including death and stroke compared favorably with outcomes of PMA-TA and SAVR patients enrolled in the PARTNER trial. This trend toward improved outcomes may be attributed to improved patient selection, individual centers surmounting the procedural learning curve, and refinements in surgical technique. PMID: 23968764 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - August 20, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Dewey TM, Bowers B, Thourani VH, Babaliaros V, Smith CR, Leon MB, Svensson LG, Tuzcu EM, Miller DC, Teirstein PS, Tyner J, Brown DL, Fontana GP, Makkar RR, Williams MR, George I, Kirtane AJ, Bavaria JE, Mack MJ Tags: Ann Thorac Surg Source Type: research

Contemporary Outcomes of Repeat Aortic Valve Replacement: A Benchmark for Transcatheter Valve-in-Valve Procedures.
CONCLUSIONS: Re-AVR is now performed with an acceptable operative mortality, which is higher than primary AVR. The overall incidence of stroke, vascular complication, and postoperative aortic insufficiency was low although higher than primary AVR. These results may serve as a benchmark for future analysis of valve-in-valve transcatheter aortic valve replacement and may have an effect on future choice of transcatheter aortic valve replacement vs re-AVR. PMID: 26209480 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - July 21, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Kaneko T, Vassileva CM, Englum B, Kim S, Yammine M, Brennan M, Suri RM, Thourani VH, Jacobs JP, Aranki S Tags: Ann Thorac Surg Source Type: research

Transapical and Transaortic Transcatheter Aortic Valve Replacement in the United States.
CONCLUSIONS: Patients undergoing TAo TAVR are older, more likely female, and have significantly higher STS predicted risk of mortality scores than patients operated on by TA access. There were no risk-adjusted differences between TA and TAo access in mortality, stroke, or readmission rates as long as 1 year after TAVR. PMID: 26233276 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - July 29, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Thourani VH, Jensen HA, Babaliaros V, Suri R, Vemulapalli S, Dai D, Brennan JM, Rumsfeld J, Edwards F, Tuzcu EM, Svensson L, Szeto WY, Herrmann H, Kirtane AJ, Kodali S, Cohen DJ, Lerakis S, Devireddy C, Sarin E, Carroll J, Holmes D, Grover FL, Williams M, Tags: Ann Thorac Surg Source Type: research

Comparison of the Performance of a Sutureless Bioprosthesis With Two Pericardial Stented Valves on Small Annuli: An In  Vitro Study.
CONCLUSIONS: All of the valves tested provided good fluid dynamic performances. The sutureless bioprosthesis provided the best performance with the least hindrance to flow behavior. From the hydrodynamic perspective, the sutureless prosthesis may present an advance in the evolution of bioprostheses, ensuring low gradients and potential for low incidence of patient-prosthesis mismatch even in small annuli. PMID: 27544288 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - August 16, 2016 Category: Cardiovascular & Thoracic Surgery Authors: Tasca G, Vismara R, Mangini A, Romagnoni C, Contino M, Redaelli A, Fiore GB, Antona C Tags: Ann Thorac Surg Source Type: research

Cognition and Cerebral Infarction in Older Adults After Surgical Aortic Valve Replacement.
CONCLUSIONS: In high-risk, aged participants undergoing surgical AVR for aortic stenosis, post-operative cognitive dysfunction was surprisingly limited and was resolved by 1-year in most. Post-operative cognitive dysfunction at 4-6 weeks was associated with more and larger acute cerebral infarcts. PMID: 30423336 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - November 10, 2018 Category: Cardiovascular & Thoracic Surgery Authors: Giovannetti T, Price CC, Fanning M, Messé S, Ratcliffe SJ, Lyon A, Kasner SE, Seidel G, Bavaria JE, Szeto WY, Hargrove WC, Acker MA, Floyd TF, DENOVO Investigators Tags: Ann Thorac Surg Source Type: research

Impact of Aortic Atherosclerosis Burden on Outcomes of Surgical Aortic Valve Replacement.
CONCLUSIONS: Moderate/severe aortic atherosclerosis was associated with an increased risk of adverse events following SAVR. Epiaortic ultrasound may serve as a useful adjunct for identifying patients who may benefit from strategies to reduce atheroembolic complications during SAVR. PMID: 31400333 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - August 6, 2019 Category: Cardiovascular & Thoracic Surgery Authors: Iribarne A, Pan S, McCullough JN, Mathew JP, Hung J, Zeng X, Voisine P, O'Gara PT, Sledz NM, Gelijns AC, Taddei-Peters WC, Messé SR, Moskowitz AJ, Thourani VH, Argenziano M, Groh MA, Giustino G, Overbey JR, DiMaio JM, Smith PK Tags: Ann Thorac Surg Source Type: research

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