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Off-pump coronary artery bypass grafting in left main stem stenosis: outcomes, concerns and controversies.
Authors: Athanasopoulos LV, Athanasiou T Abstract Left main stem (LMS) disease is known to be a poor prognostic factor in terms of morbidity or mortality. Traditionally, it has been treated with constitution of bypass to provide required haemodynamic stability. We searched the literature for evidence on off-pump (OFP) surgery for treating this high-risk group of patients focusing in our review on postoperative outcomes, concerns and controversies. The majority of the studies identified showed favourable or equal outcomes of OFP when compared to conventional approach. All of the studies, apart from two, which showed...
Source: Journal of Thoracic Disease - December 14, 2016 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

The future of off-pump coronary artery bypass grafting: a North American perspective.
Authors: Yanagawa B, Nedadur R, Puskas JD Abstract Off-pump coronary artery bypass graft (OPCAB) is currently performed routinely in a minority of specialized centers and in many more centers, utilized only when a porcelain aorta mandates a no-touch aortic technique. The OPCAB literature can be summarized as follows: (I) large-scale randomized trials in relatively low risk patients that include surgeons with a range of experience demonstrating no consistent beneficial differences in major cardiovascular and cerebrovascular outcomes but lower transfusion rates and shorter length of stay, tempered by some reports of ...
Source: Journal of Thoracic Disease - December 14, 2016 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Current outcomes of off-pump versus on-pump coronary artery bypass grafting: evidence from randomized controlled trials.
Authors: Fudulu D, Benedetto U, Pecchinenda GG, Chivasso P, Bruno VD, Rapetto F, Bryan A, Angelini GD Abstract Coronary artery bypass grafting remains the standard treatment for patients with extensive coronary artery disease. Coronary surgery without use of cardiopulmonary bypass avoids the deleterious systemic inflammatory effects of the extracorporeal circuit. However there is an ongoing debate surrounding the clinical outcomes after on-pump versus off-pump coronary artery bypass (ONCAB versus OPCAB) surgery. The current review is based on evidence from randomized controlled trials (RCTs) and meta-analyses of ra...
Source: Journal of Thoracic Disease - December 14, 2016 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

On-pump beating heart versus conventional coronary artery bypass grafting: comparative study on early and long-term clinical outcomes.
Conclusions: The OPB strategy may be as safe and effective as the conventional strategy during CABG among patients with similar risk profiles. A prospective randomized trial is warranted to better ascertain the beneficial impact of OPB-CABG as both a viable and a durable alternative strategy to C-CABG. PMID: 29997927 [PubMed]
Source: Journal of Thoracic Disease - July 14, 2018 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Triglyceride glucose index for predicting cardiovascular outcomes in patients with coronary artery disease.
Conclusions: The present study, firstly, showed that TyG index was positively associated with future CVEs, suggesting that TyG may be a useful marker for predicting clinical outcomes in patients with CAD. PMID: 30622785 [PubMed]
Source: Journal of Thoracic Disease - January 11, 2019 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Early surgical myocardial revascularization in non-ST-segment elevation acute coronary syndrome.
Conclusions: Early revascularized patients showed a higher level of illness. However, results of early CABG were comparable to those following delayed revascularization. Moreover, EuroSCORE II was determined as independent risk factors for mortality. PMID: 31903232 [PubMed]
Source: Journal of Thoracic Disease - January 8, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Association of early elevated cardiac troponin I concentration and longitudinal change after off-pump coronary artery bypass grafting and adverse events: a prospective cohort study.
Conclusions: Longitudinal change in cTnI levels within 24 hours and early cTnI concentrations, even less than 1 hour after CABG, are associated with adverse events. These data will be useful in identifying patients at an increased risk of complications. PMID: 33282356 [PubMed]
Source: Journal of Thoracic Disease - December 8, 2020 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Minimally invasive and robotic coronary artery bypass grafting-a 25-year review
J Thorac Dis. 2021 Mar;13(3):1922-1944. doi: 10.21037/jtd-20-1535.ABSTRACTDuring the mid-1990s cardiac surgery started exploring minimally invasive methods for coronary artery bypass grafting (CABG) and has over a 25-year period developed highly differentiated and less traumatic operations. Instead of the traditional sternotomy mini-incisions on the chest or ports are placed, surgery on the beating heart is applied, sophisticated remote access heart lung machine systems as well as videoscopic units are available, and robotic technology enables completely endoscopic approaches. This review describes these methods, reports o...
Source: Journal of Thoracic Disease - April 12, 2021 Category: Respiratory Medicine Authors: Johannes Bonatti Stephanie Wallner Ingo Crailsheim Martin Grabenw öger Bernhard Winkler Source Type: research

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