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Life satisfaction and its influencing factors of middle-aged and elderly stroke patients in China: a national cross-sectional survey
Conclusions Our study indicates the importance of improving the overall health of patients who had a stroke and mediating factors, such as pain management, and work ability, spouse and children relationship in improving the life satisfaction of patients in the poststroke rehabilitation.
Source: BMJ Open - August 3, 2022 Category: General Medicine Authors: Liu, Y., Liu, J., Zhou, S., Xu, X., Cheng, Y., Yi, Y., Zou, G. Tags: Open access, Public health Source Type: research

Surgical interventions for symptomatic mild to moderate knee osteoarthritis.
CONCLUSIONS: The review found no placebo-or sham-controlled trials of surgery in participants with symptomatic mild to moderate knee osteoarthritis. There was low quality evidence that there may be no evidence of a difference between arthroscopic partial meniscectomy surgery and a home exercise program for the treatment of this condition. Similarly, low-quality evidence from a few small trials indicates there may not be any benefit of arthroscopic surgery over other non-surgical treatments including saline irrigation and hyaluronic acid injection, or one type of surgery over another. We are uncertain of the risk of adverse...
Source: Cochrane Database of Systematic Reviews - July 18, 2019 Category: General Medicine Authors: Palmer JS, Monk AP, Hopewell S, Bayliss LE, Jackson W, Beard DJ, Price AJ Tags: Cochrane Database Syst Rev Source Type: research

Interventions for treating urinary incontinence after stroke in adults.
CONCLUSIONS: There is insufficient evidence to guide continence care of adults in the rehabilitative phase after stroke. As few trials tested the same intervention, conclusions are drawn from few, usually small, trials. CIs were wide, making it difficult to ascertain if there were clinically important differences. Only four trials had adequate allocation concealment and many were limited by poor reporting, making it impossible to judge the extent to which they were prone to bias. More appropriately powered, multicentre trials of interventions are required to provide robust evidence for interventions to improve urinary inco...
Source: Cochrane Database of Systematic Reviews - February 1, 2019 Category: General Medicine Authors: Thomas LH, Coupe J, Cross LD, Tan AL, Watkins CL Tags: Cochrane Database Syst Rev Source Type: research

Epidural therapy for the treatment of severe pre-eclampsia in non labouring women.
CONCLUSIONS: Currently, there is insufficient evidence from randomised controlled trials to evaluate the effectiveness, safety or cost of using epidural therapy for treating severe pre-eclampsia in non-labouring women.High-quality randomised controlled trials are needed to evaluate the use of epidural agents as therapy for treatment of severe pre-eclampsia. The rationale for the use of epidural is well-founded. However there is insufficient evidence from randomised controlled trials to show that the effect of epidural translates into improved maternal and fetal outcomes. Thus, there is a need for larger, well-designed stud...
Source: Cochrane Database of Systematic Reviews - November 28, 2017 Category: General Medicine Authors: Ray A, Ray S Tags: Cochrane Database Syst Rev Source Type: research

Self-management support interventions for persons with chronic disease: an evidence-based analysis.
CONCLUSIONS: The Stanford CDSMP led to statistically significant, albeit clinically minimal, short-term improvements across a number of health status measures (including some measures of health-related quality of life), healthy behaviours, and self-efficacy compared to usual care. However, there was no evidence to suggest that the CDSMP improved health care utilization. More research is needed to explore longer-term outcomes, the impact of self-management on clinical outcomes, and to better identify responders and non-responders. PLAIN LANGUAGE SUMMARY: Self-management support interventions are becoming more common as ...
Source: Ontario Health Technology Assessment Series - December 20, 2015 Category: Journals (General) Tags: Ont Health Technol Assess Ser Source Type: research

Is 120 mm Hg the new BP target? What headlines aren’t telling you
The results of the SPRINT trial are in, and you’ve probably heard that making 120 mm Hg the new blood pressure target helped lower mortality rates. Yet the study outcomes apply only to a specific subset of patients with hypertension. See whether or not your patients may fit into this category. In the much-anticipated results of the SPRINT trial, the relative risk of death from cardiovascular causes was 43 percent lower for patients receiving more intensive treatment for a 120 mm Hg target versus those who received standard treatment for a 140 mm Hg target. While these results were unexpected and are noteworthy, wh...
Source: AMA Wire - November 11, 2015 Category: Journals (General) Authors: amamod Source Type: news

Constraint-induced movement therapy for upper extremities in people with stroke.
CONCLUSIONS: CIMT is a multi-faceted intervention where restriction of the less affected limb is accompanied by increased exercise tailored to the person's capacity. We found that CIMT was associated with limited improvements in motor impairment and motor function, but that these benefits did not convincingly reduce disability. This differs from the result of our previous meta-analysis where there was a suggestion that CIMT might be superior to traditional rehabilitation. Information about the long-term effects of CIMT is scarce. Further trials studying the relationship between participant characteristics and improved outc...
Source: Cochrane Database of Systematic Reviews - October 8, 2015 Category: Journals (General) Authors: Corbetta D, Sirtori V, Castellini G, Moja L, Gatti R Tags: Cochrane Database Syst Rev Source Type: research

Deep vein thrombosis and pulmonary embolism in the military patient
Discussion Prompt initiation of anticoagulation reduces symptoms, rates of recurrent VTE and death but treatment must be balanced against the risk of major haemorrhage. Military operations expose personnel to a unique combination of risk factors for VTE and operating in austere environments can increase the challenge of diagnosis, prognostication and management. Furthermore, there are implications for troop attrition, operational readiness and return to work.
Source: Journal of the Royal Army Medical Corps - August 20, 2015 Category: Journals (General) Authors: Bauld, R. A., Patterson, C., Naylor, J., Rooms, M., Bell, D. Tags: Epidemiologic studies, Drugs: cardiovascular system, Drugs: CNS (not psychiatric), Pain (neurology), Stroke, Hypertension, Venous thromboembolism, Pulmonary embolism, Pulmonary hypertension, Internet Review Source Type: research

Levetiracetam for neuropathic pain in adults.
CONCLUSIONS: The amount of evidence for levetiracetam in neuropathic pain conditions was very small and potentially biased because of the methods of analysis used in the studies. There was no indication that levetiracetam was effective in reducing neuropathic pain, but it was associated with an increase in participants who experienced adverse events and who withdrew due to adverse events. PMID: 25000215 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - July 7, 2014 Category: Journals (General) Authors: Wiffen PJ, Derry S, Moore RA, Lunn MP Tags: Cochrane Database Syst Rev Source Type: research