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Source: Neurology
Condition: Pregnancy

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Total 22 results found since Jan 2013.

Mechanisms and Outcomes of Ischemic Stroke in Pregnancy and Postpartum: A Retrospective Cross-Sectional Study (P3.070)
CONCLUSIONS: Women with pregnancy-associated ischemic strokes were younger and had fewer vascular risk factors when compared with other young women with ischemic strokes. Outcomes were similar in the two groups, with a substantial proportion of poor outcomes in both groups. Our results are limited by the small sample size and retrospective nature of the study. Larger studies are needed to better characterize the pathophysiology of pregnancy-associated stroke.Disclosure: Dr. Miller has nothing to disclose. Dr. Yaghi has nothing to disclose. Dr. Boehme has nothing to disclose. Dr. Willey has nothing to disclose. Dr. Elkind h...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Miller, E., Yaghi, S., Boehme, A., Willey, J., Elkind, M., Marshall, R. Tags: Cerebrovascular Disease and Interventional Neurology: Ischemic Stroke Outcome Source Type: research

Risk of Pregnancy-Associated Stroke Across Age Groups: Population-Based Data from New York State (S4.007)
Conclusions: Younger peripartum women, but not older women, are at increased risk of stroke compared to non-pregnant contemporaries. These results suggest that pregnancy itself does not increase the risk of stroke in older women, though they could reflect a tendency for older pregnant women to have above-average cardiovascular health. More research is needed to investigate why younger women may have increased risk of PAS.Disclosure: Dr. Miller has nothing to disclose. Dr. Gatollari has nothing to disclose. Dr. Too has nothing to disclose. Dr. Boehme has nothing to disclose. Dr. Colello has nothing to disclose. Dr. Leffert ...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Miller, E., Gatollari, H., Too, G., Boehme, A., Colello, A., Leffert, L., Elkind, M., Willey, J. Tags: Health Disparities and Sex Differences in Stroke Source Type: research

Hypertensive Disorders in Pregnancy and Future Risk of Stroke: A Systematic Review (P2.114)
CONCLUSIONS: Hypertension in pregnancy likely carries an increased risk for stroke in later life, especially when associated with pre-eclampsia/eclampsia. There may be benefit in targeting these women for close risk-factor monitoring and control beyond the post-partum period.Disclosure: Dr. Ganesh has nothing to disclose. Dr. Sarna has nothing to disclose. Dr. Mehta has nothing to disclose. Dr. Smith has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Ganesh, A., Sarna, N., Mehta, R., Smith, E. Tags: Cerebrovascular Disease and Interventional Neurology: Childhood and Young Adult Source Type: research

Clinical Characteristics of PFO Stroke in Pregnancy (P2.274)
CONCLUSIONS: PFO may pose unique risks compared to non-PFO related stroke in pregnancy. Novel risk factors such as May-Thurner’s anatomy, which promote venous clotting with the increase in abdominal girth are important during pregnancy. For high risk individuals (such as those with known hypercoagulable state), screening for PFO may be of clinical utility in preventing strokes. Further studies are ongoing to validate these preliminary findings. Study Supported by: None.Disclosure: Dr. Chen has nothing to disclose. Dr. Deng has nothing to disclose. Dr. Wickham has nothing to disclose. Dr. McMullin D has nothing to dis...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Chen, L., Deng, W., Wickham, T., McMullin D, D., Eng H, L., Buonanno, F., Ning, M. Tags: Cerebrovascular Disease and Interventional Neurology: PFO and Other Cardiac Disease Source Type: research

Stroke Outcomes and Usage of IV Alteplase during Pregnancy in the Nationwide Inpatient Sample 2005-2010 (P3.100)
ConclusionsStroke remains a serious complication in pregnancy, and mortality is increasing. Usage of tPA for AIS during pregnancy is minimal, with increased mortality compared to all strokes in pregnancy. Research efforts are needed to improve stroke outcomes during pregnancy.Disclosure: Dr. Ouyang has nothing to disclose. Dr. Knopf has nothing to disclose. Dr. Conners has nothing to disclose. Dr. Cutting has received personal compensation for activities with F1000. Dr. Lee has nothing to disclose. Dr. Smit has nothing to disclose. Dr. Kuklina has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Song, S., Ouyang, B., Knopf, T., Conners, J., Cutting, S., Lee, V., Smit, L., Kuklina, E. Tags: Cerebrovascular Disease and Interventional Neurology: t-PA Source Type: research

Risk of Pregnancy-Associated Stroke Across Age Groups: Population-Based Data from New York State (I5.005)
Conclusions: Younger peripartum women, but not older women, are at increased risk of stroke compared to non-pregnant contemporaries. These results suggest that pregnancy itself does not increase the risk of stroke in older women, though they could reflect a tendency for older pregnant women to have above-average cardiovascular health. More research is needed to investigate why younger women may have increased risk of PAS.Disclosure: Dr. Miller has nothing to disclose. Dr. Gatollari has nothing to disclose. Dr. Too has nothing to disclose. Dr. Boehme has nothing to disclose. Dr. Colello has nothing to disclose. Dr. Leffert ...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Miller, E., Gatollari, H., Too, G., Boehme, A., Colello, A., Leffert, L., Elkind, M., Willey, J. Tags: Sex-related Factors in Neurological Disease Data Blitz Presentations Source Type: research

Pregnancy in Advanced Age Increases the Risk of Hemorrhagic Stroke in Post-Menopausal Women. Analysis of Women's Health Initiative Study (P6.005)
Conclusions: Women with pregnancy in advanced age have a higher risk for hemorrhagic stroke in post-menopausal period.Disclosure: Dr. Qureshi has nothing to disclose. Dr. Saeed has nothing to disclose. Dr. Malik has nothing to disclose. Dr. Degenhardt has nothing to disclose. Dr. Axt-Fliedner has nothing to disclose. Dr. Kohl has nothing to disclose. Dr. Suri has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Qureshi, A., Saeed, O., Malik, A., Degenhardt, J., Axt-Fliedner, R., Kohl, T., Suri, M. Tags: Cerebrovascular Disease and Interventional Neurology Poster Discussion Session Source Type: research

Ischemic Stroke in Pregnancy and Postpartum: A Descriptive Case Series (P1.079)
CONCLUSIONS: In our series of 19 pregnancy-associated ischemic strokes, mechanisms appeared unrelated to traditional vascular risk factors, and there was a substantial proportion of poor outcomes. Strokes were commonest in the 12 weeks postpartum, almost one third of which occurred following a miscarriage. Further exploration with a larger cohort is planned.Disclosure: Dr. Miller has nothing to disclose. Dr. Yaghi has nothing to disclose. Dr. Boehme has nothing to disclose. Dr. Willey has nothing to disclose. Dr. Elkind has received personal compensation for activities with BMS-Pfizer Partnership, Janssen Pharmaceuticals, ...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Miller, E., Yaghi, S., Boehme, A., Willey, J., Elkind, M., Marshall, R. Tags: Cerebrovascular Disease and Interventional Neurology: Epidemiology Source Type: research

Postpartum cardiomyopathy with cardioembolic stroke (p3.298)
Conclusions:Peripartum cardiomyopathy is a rare cause of stroke. Though seldom described, it should be considered in appropriate female patients presenting with neurological deficits. Definitive therapy with anticoagulation should be considered to prevent further complications.Disclosure: Dr. Kumbham has nothing to disclose. Dr. Sharma has nothing to disclose. Dr. Patel has nothing to disclose. Dr. Masangkay has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Kumbham, P., Sharma, B., Patel, A., Masangkay, N. Tags: Cerebrovascular Disease Case Reports II Source Type: research

Antiphospholipid Syndrome-Associated Crescendo Stroke Events Treated with Rituximab (P4.351)
Discussion APS is an autoimmune condition associated with persistent antiphospholipid antibodies, characterised by thrombosis and pregnancy morbidity [1].Regarding APS and stroke the optimal antithrombotic agent, intensity of anticoagulation, and duration of treatment remains controversial[2]. Analysis of the APASS subgroup in the WARS study found aspirin and warfarin to be equally effective agents for secondary stroke prevention [2]. The majority of panel members at the International Congress on Antiphospholipid Antibodies recommended warfarin or combination aspirin and warfarin for patients with definite APS and arterial...
Source: Neurology - April 3, 2016 Category: Neurology Authors: O' Connor, A., Murphy, G., Cronin, S. Tags: Cerebrovascular Case Reports Source Type: research

Risk Factors for Pregnancy-Associated Stroke in Women with Preeclampsia: a Case-Control Study (S15.007)
Conclusions:Chronic hypertension, underlying prothrombotic conditions and infections increase PAS risk in women with PEC. These women may warrant closer postpartum monitoring, due to high PAS-associated mortality in this population.Disclosure: Dr. Miller has nothing to disclose. Dr. Gatollari has nothing to disclose. Dr. Too has nothing to disclose. Dr. Boehme has nothing to disclose. Dr. Leffert has nothing to disclose. Dr. Elkind has received personal compensation in an editorial capacity for Neurology. Dr. Willey has received personal compensation for activities with Heartware Incoporated as a consultant, from Claret Me...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Miller, E., Gatollari, H., Too, G., Boehme, A., Leffert, L., Elkind, M., Willey, J. Tags: Neuroepidemiology Source Type: research

Pregnancy Associated Cerebral Ischemia in Women with Sickle Cell Disease (P2.113)
Conclusions:There appears to be high rates of cerebral ischemia and abortion or miscarriage among pregnant women with sickle cell disease but occurrence of cerebral ischemia does not influence subsequent abortion or miscarriage.Disclosure: Dr. Zafar has nothing to disclose. Dr. Malik has nothing to disclose. Dr. Suri has nothing to disclose. Dr. Qureshi has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Zafar, T., Adil, M., Suri, M., Qureshi, A. Tags: Cerebrovascular Disease and Interventional Neurology: Childhood and Young Adult Source Type: research

Transient Neurologic Deficit Presenting with Cortical Vein Thrombosis Caused by Intracranial Hypotension: Case Report (P1.028)
CONCLUSION We hypothesized that intracranial hypotension led to venous engorgement (based on the Monroe-Kelli doctrine) and the subsequent cortical vein thrombosis, which then produced vasogenic edema, cortical irritability, and focal seizure that mimicked ischemic stroke. Based on our findings, clinicians should consider intracranial hypotension in patients presenting with dural sinus or cortical vein thrombosis, and orthostatic headache or imaging findings of dural enhancement.Disclosure: Dr. Plancher has nothing to disclose. Dr. Flaherty has received personal compensation for activities with CSL Behring as a consultant ...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Plancher, J. M.-O., Flaherty, M. Tags: Cerebrovascular Disease and Interventional Neurology: Case Reports Source Type: research

Persistent brain injury after preeclampsia
Preeclampsia, a common hypertensive disorder of pregnancy, contributes substantially to maternal and fetal morbidity and mortality worldwide. While the cause of preeclampsia remains debated, it is clear that there are both placental and maternal causes of preeclampsia, making it a heterogeneous disease.1 Abnormal trophoblast invasion of spiral arteries during placentation leads to placental ischemia and release of placental-derived soluble factors into the maternal circulation.2 These circulating proinflammatory and antiangiogenic factors appear to produce maternal vascular inflammation and cause endothelial dysfunction th...
Source: Neurology - March 27, 2017 Category: Neurology Authors: Cipolla, M. J., Biller, J. Tags: Stroke prevention, MRI, All Cerebrovascular disease/Stroke EDITORIALS Source Type: research

Long-term cerebral white and gray matter changes after preeclampsia
Conclusion: A history of preeclampsia is associated with temporal lobe white matter changes and reduced cortical volume in young women, which is out of proportion to their classic cardiovascular risk profile. The severity of changes is proportional to time since pregnancy, which would be consistent with continued accumulation of damage after pregnancy.
Source: Neurology - March 27, 2017 Category: Neurology Authors: Siepmann, T., Boardman, H., Bilderbeck, A., Griffanti, L., Kenworthy, Y., Zwager, C., McKean, D., Francis, J., Neubauer, S., Yu, G. Z., Lewandowski, A. J., Sverrisdottir, Y. B., Leeson, P. Tags: Stroke prevention, MRI, All Cerebrovascular disease/Stroke ARTICLE Source Type: research