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Infectious Disease: COVID-19
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Total 5889 results found since Jan 2013.
Genetic Architecture of Ischaemic Strokes after COVID-19 Shows Similarities with Large Vessel Strokes
Int J Mol Sci. 2023 Aug 30;24(17):13452. doi: 10.3390/ijms241713452.ABSTRACTWe aimed to analyse whether patients with ischaemic stroke (IS) occurring within eight days after the onset of COVID-19 (IS-COV) are associated with a specific aetiology of IS. We used SUPERGNOVA to identify genome regions that correlate between the IS-COV cohort (73 IS-COV cases vs. 701 population controls) and different aetiological subtypes. Polygenic risk scores (PRSs) for each subtype were generated and tested in the IS-COV cohort using PRSice-2 and PLINK to find genetic associations. Both analyses used the IS-COV cohort and GWAS from MEGASTRO...
Source: Atherosclerosis - September 9, 2023 Category: Cardiology Authors: Laia Lluci à-Carol Elena Mui ño Natalia Cullell Jara C árcel-Márquez Miquel Lled ós Cristina Gallego-Fabrega Jes ús Martin-Campos Joan Mart í-Fàbregas Ana Aguilera-Sim ón Anna M Planas Marta L DeDiego Alicia de Felipe Mimbrera Jaime Masjuan Sebas Source Type: research
Anticoagulation strategies in COVID-19 infected patients receiving ECMO support
CONCLUSION: In hospitalized patients with COVID-19-associated acute respiratory distress syndrome (ARDS) on VV ECMO support, the use of bivalirudin showed to be a viable anticoagulation alternative in terms of efficacy compared to UFH and resulted in a favorable safety profile with lower rates of bleeding and thrombotic events.PMID:37682210 | DOI:10.1051/ject/2023027
Source: Journal of Extra-Corporeal Technology - September 8, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Dayne Diaz Jenny Martinez Grant Bushman William R Wolowich Source Type: research
Bioinformatics analysis of carotid vulnerable plaques associated with the SARS-CoV-2 Pattern
Gene. 2023 Aug 31:147754. doi: 10.1016/j.gene.2023.147754. Online ahead of print.ABSTRACTThe rupture of carotid artery vulnerable plaque plays a critical role in ischemic stroke, and the widely spread new coronavirus in recent years plays a certain role in the development of human carotid artery vulnerable plaque, we screened out 27 differential expression genes (DEGs) of stable plaque and vulnerable plaque associated with the new coronavirus. Through the construction of the protein-protein interaction (PPI) network, the Cathepsin B (CTSB) and Niemann-Pick Disease Type 2 (NPC2) were identified as crucial expression genes, ...
Source: Gene - September 2, 2023 Category: Genetics & Stem Cells Authors: Tao Jiang Jiaming Huang Shupeng Li Qiushi Xu Tianding Zhang Xianwei Wang Dong Chen Source Type: research
