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Source: Journal of Integrative Neuroscience
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Total 1980 results found since Jan 2013.
Autophagy in Intracerebral Hemorrhage: From Mechanism to Regulation
J Integr Neurosci. 2023 Sep 18;22(5):134. doi: 10.31083/j.jin2205134.ABSTRACTIntracerebral hemorrhage (ICH) is the most lethal type of stroke. Secondary injury from ICH determines the recovery, but there is still a lack of effective treatment. The identification of new therapeutic targets may address the current dilemma. The process of autophagy is mediated through the lysosomal pathway and is used to maintain cell homeostasis. Recent studies have advanced our knowledge of autophagy, and in particular its involvement in cell physiology and pathology. Autophagy involves multiple targets and signaling pathways and occurs in ...
Source: Journal of Integrative Neuroscience - September 21, 2023 Category: Neuroscience Authors: Jia Zheng Wei Zou Xueping Yu Source Type: research
Efficacy and Safety of Repetitive Transcranial Magnetic Stimulation for Poststroke Memory Disorder: A Meta-Analysis and Systematic Review
CONCLUSIONS: rTMS may improve memory function, global cognition, and the ability to perform ADL in patients with PSMD. LF-rTMS and HF-rTMS may have equal efficacy for treatment of PSMD. Future studies should consider extending the follow-up period to explore the safety and long-term efficacy of rTMS for treatment of PSMD and the appropriate choice of placebo for clinical trials of this treatment.PMID:37735134 | DOI:10.31083/j.jin2205131
Source: Journal of Integrative Neuroscience - September 21, 2023 Category: Neuroscience Authors: Haihua Xie Shiyang Luo Dan Xiong Pan Zhu Jie Chen Xin Tang Jie Tan Ning Zhao Source Type: research
Single-Cell RNA-Seq Reveals Changes in Cell Subsets in the Cortical Microenvironment during Acute Phase of Ischemic Stroke Rats
CONCLUSIONS: ScRNA-seq revealed the diversity of cell differentiation and the unique information of cell subpopulations in the cortex of rats with acute ischemic stroke, providing novel insight into the pathological process and drug discovery in stroke.PMID:37735120 | DOI:10.31083/j.jin2205128
Source: Journal of Integrative Neuroscience - September 21, 2023 Category: Neuroscience Authors: Yijin Zhao Chongwu Xiao Hui Chen Rui Zhu Meimei Zhang Haining Liu Xiaofeng Zhang Qing Zeng Guozhi Huang Source Type: research
Linkage Disequilibrium between LDLR < em > rs688 < /em > and < em > AvaII < /em > Genes and its Significant Association with Ischemic Stroke
CONCLUSIONS: Linkage disequilibrium existed between LDLR rs688 and AvaII genes. With the wild type gene (WT) (rs688/AvaII: CC/TT) as reference, rs688/AvaII: CT/TC, CT/CC and TT/CC increased the risk of ischemic stroke, which might be a genetic marker used for the screen of high-risk population contributing to the prevention of the disease.PMID:37519169 | DOI:10.31083/j.jin2204094
Source: Journal of Integrative Neuroscience - July 31, 2023 Category: Neuroscience Authors: Yabin Chen Hehui Cai Jianming Zhang Yongfa Su Yibo Wu Zhenzhong Lin Zhishan Zhang Source Type: research
Screening Serum Biomarkers for Rats Preconditioned with Hyperbaric Oxygen: Potential of Predicting Prognosis for Stroke
CONCLUSIONS: Haemopexin may be developed as a predictive biomarker that indicated the effectiveness of a preconditioning strategy against cerebral ischaemic injury.PMID:37519161 | DOI:10.31083/j.jin2204103
Source: Journal of Integrative Neuroscience - July 31, 2023 Category: Neuroscience Authors: Beibei Dong Yuanyuan Bai Qi Jia Lin Su Xinyue Zhang Shiquan Wang Zongping Fang Source Type: research
The Role of Mitochondrial Biogenesis in Ischemic Stroke
J Integr Neurosci. 2023 Jul 5;22(4):88. doi: 10.31083/j.jin2204088.ABSTRACTIschaemic stroke is a sudden neurological disorder caused by localised cerebral ischaemia and persistent cerebral infarction. Occlusion of large arteries due to atherothrombosis, cerebral embolism (i.e., embolic infarction), no thrombotic occlusion in small, deep cerebral arteries (i.e., lacunar infarction), and stenosis of proximal arteries due to hypotension leading to decreased cerebral blood flow in arterial supply zones are the most common causes of ischemic stroke (i.e., hemodynamic stroke). It is now known that organelles play an important ro...
Source: Journal of Integrative Neuroscience - July 31, 2023 Category: Neuroscience Authors: Behrouz Shademan Cigir Biray Avci Vahidreza Karamad Gholamreza Jahangirzadeh Soureh Jalhe Bagheri Hamzyan Olia Farzaneh Esmaily Alireza Nourazarian Masoud Nikanfar Source Type: research
Linkage Disequilibrium between LDLR < em > rs688 < /em > and < em > AvaII < /em > Genes and its Significant Association with Ischemic Stroke
CONCLUSIONS: Linkage disequilibrium existed between LDLR rs688 and AvaII genes. With the wild type gene (WT) (rs688/AvaII: CC/TT) as reference, rs688/AvaII: CT/TC, CT/CC and TT/CC increased the risk of ischemic stroke, which might be a genetic marker used for the screen of high-risk population contributing to the prevention of the disease.PMID:37519169 | DOI:10.31083/j.jin2204094
Source: Journal of Integrative Neuroscience - July 31, 2023 Category: Neuroscience Authors: Yabin Chen Hehui Cai Jianming Zhang Yongfa Su Yibo Wu Zhenzhong Lin Zhishan Zhang Source Type: research
Screening Serum Biomarkers for Rats Preconditioned with Hyperbaric Oxygen: Potential of Predicting Prognosis for Stroke
CONCLUSIONS: Haemopexin may be developed as a predictive biomarker that indicated the effectiveness of a preconditioning strategy against cerebral ischaemic injury.PMID:37519161 | DOI:10.31083/j.jin2204103
Source: Journal of Integrative Neuroscience - July 31, 2023 Category: Neuroscience Authors: Beibei Dong Yuanyuan Bai Qi Jia Lin Su Xinyue Zhang Shiquan Wang Zongping Fang Source Type: research
The Role of Mitochondrial Biogenesis in Ischemic Stroke
J Integr Neurosci. 2023 Jul 5;22(4):88. doi: 10.31083/j.jin2204088.ABSTRACTIschaemic stroke is a sudden neurological disorder caused by localised cerebral ischaemia and persistent cerebral infarction. Occlusion of large arteries due to atherothrombosis, cerebral embolism (i.e., embolic infarction), no thrombotic occlusion in small, deep cerebral arteries (i.e., lacunar infarction), and stenosis of proximal arteries due to hypotension leading to decreased cerebral blood flow in arterial supply zones are the most common causes of ischemic stroke (i.e., hemodynamic stroke). It is now known that organelles play an important ro...
Source: Journal of Integrative Neuroscience - July 31, 2023 Category: Neuroscience Authors: Behrouz Shademan Cigir Biray Avci Vahidreza Karamad Gholamreza Jahangirzadeh Soureh Jalhe Bagheri Hamzyan Olia Farzaneh Esmaily Alireza Nourazarian Masoud Nikanfar Source Type: research
Screening Serum Biomarkers for Rats Preconditioned with Hyperbaric Oxygen: Potential of Predicting Prognosis for Stroke
CONCLUSIONS: Haemopexin may be developed as a predictive biomarker that indicated the effectiveness of a preconditioning strategy against cerebral ischaemic injury.PMID:37519161 | DOI:10.31083/j.jin2204103
Source: Journal of Integrative Neuroscience - July 31, 2023 Category: Neuroscience Authors: Beibei Dong Yuanyuan Bai Qi Jia Lin Su Xinyue Zhang Shiquan Wang Zongping Fang Source Type: research
The Role of Mitochondrial Biogenesis in Ischemic Stroke
J Integr Neurosci. 2023 Jul 5;22(4):88. doi: 10.31083/j.jin2204088.ABSTRACTIschaemic stroke is a sudden neurological disorder caused by localised cerebral ischaemia and persistent cerebral infarction. Occlusion of large arteries due to atherothrombosis, cerebral embolism (i.e., embolic infarction), no thrombotic occlusion in small, deep cerebral arteries (i.e., lacunar infarction), and stenosis of proximal arteries due to hypotension leading to decreased cerebral blood flow in arterial supply zones are the most common causes of ischemic stroke (i.e., hemodynamic stroke). It is now known that organelles play an important ro...
Source: Journal of Integrative Neuroscience - July 31, 2023 Category: Neuroscience Authors: Behrouz Shademan Cigir Biray Avci Vahidreza Karamad Gholamreza Jahangirzadeh Soureh Jalhe Bagheri Hamzyan Olia Farzaneh Esmaily Alireza Nourazarian Masoud Nikanfar Source Type: research
Linkage Disequilibrium between LDLR < em > rs688 < /em > and < em > AvaII < /em > Genes and its Significant Association with Ischemic Stroke
CONCLUSIONS: Linkage disequilibrium existed between LDLR rs688 and AvaII genes. With the wild type gene (WT) (rs688/AvaII: CC/TT) as reference, rs688/AvaII: CT/TC, CT/CC and TT/CC increased the risk of ischemic stroke, which might be a genetic marker used for the screen of high-risk population contributing to the prevention of the disease.PMID:37519169 | DOI:10.31083/j.jin2204094
Source: Journal of Integrative Neuroscience - July 31, 2023 Category: Neuroscience Authors: Yabin Chen Hehui Cai Jianming Zhang Yongfa Su Yibo Wu Zhenzhong Lin Zhishan Zhang Source Type: research
Screening Serum Biomarkers for Rats Preconditioned with Hyperbaric Oxygen: Potential of Predicting Prognosis for Stroke
CONCLUSIONS: Haemopexin may be developed as a predictive biomarker that indicated the effectiveness of a preconditioning strategy against cerebral ischaemic injury.PMID:37519161 | DOI:10.31083/j.jin2204103
Source: Journal of Integrative Neuroscience - July 31, 2023 Category: Neuroscience Authors: Beibei Dong Yuanyuan Bai Qi Jia Lin Su Xinyue Zhang Shiquan Wang Zongping Fang Source Type: research
The Role of Mitochondrial Biogenesis in Ischemic Stroke
J Integr Neurosci. 2023 Jul 5;22(4):88. doi: 10.31083/j.jin2204088.ABSTRACTIschaemic stroke is a sudden neurological disorder caused by localised cerebral ischaemia and persistent cerebral infarction. Occlusion of large arteries due to atherothrombosis, cerebral embolism (i.e., embolic infarction), no thrombotic occlusion in small, deep cerebral arteries (i.e., lacunar infarction), and stenosis of proximal arteries due to hypotension leading to decreased cerebral blood flow in arterial supply zones are the most common causes of ischemic stroke (i.e., hemodynamic stroke). It is now known that organelles play an important ro...
Source: Journal of Integrative Neuroscience - July 31, 2023 Category: Neuroscience Authors: Behrouz Shademan Cigir Biray Avci Vahidreza Karamad Gholamreza Jahangirzadeh Soureh Jalhe Bagheri Hamzyan Olia Farzaneh Esmaily Alireza Nourazarian Masoud Nikanfar Source Type: research
