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Source: Atherosclerosis
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Total 2124 results found since Jan 2013.
Association Between Intensity of Low-Density Lipoprotein Cholesterol Reduction With Statin-Based Therapies and Secondary Stroke Prevention: A Meta-analysis of Randomized Clinical Trials
CONCLUSIONS AND RELEVANCE: This study suggests that the benefits and risks of more intensive LDL-C-lowering statin-based therapies for recurrent stroke risk reduction might be more favorable than the benefits and risks of less intensive LDL-C-lowering statin-based therapies, especially for patients with evidence of atherosclerosis.PMID:35188949 | DOI:10.1001/jamaneurol.2021.5578
Source: Atherosclerosis - February 21, 2022 Category: Cardiology Authors: Meng Lee Chun-Yu Cheng Yi-Ling Wu Jiann-Der Lee Chia-Yu Hsu Bruce Ovbiagele Source Type: research
Association Between Carotid Artery Perivascular Fat Density and Embolic Stroke of Undetermined Source
CONCLUSION: We found increased density in the fat surrounding carotid artery ipsilateral to stroke compared with contralateral in ESUS, suggesting the presence of an inflammatory reaction that extends beyond the vessel lumen in patients with ESUS with a risk factor profile similar to LAA strokes.PMID:35250789 | PMC:PMC8894862 | DOI:10.3389/fneur.2021.765962
Source: Atherosclerosis - March 7, 2022 Category: Cardiology Authors: Xiaohong Hu Jianhui Chen Huajun Fu Yinjuan Chen Daofeng Fan Yangui Chen Chaoxiong Shen Source Type: research
Association of Stroke Subtype With Hemorrhagic Transformation Mediated by Thrombectomy Pass: Data From the ANGEL-ACT Registry
CONCLUSIONS: Stroke subtype is an independent risk factor for HT within 24 hours following endovascular treatment among acute large vessel occlusion patients. Mediation analyses propose that stroke subtype contributes to HT partly through thrombectomy pass, suggesting a possible pathomechanistic link.PMID:35354298 | DOI:10.1161/STROKEAHA.121.037411
Source: Atherosclerosis - March 31, 2022 Category: Cardiology Authors: Xu Tong W Scott Burgin Zeguang Ren Baixue Jia Xuelei Zhang Xiaochuan Huo Gang Luo Anxin Wang Yijun Zhang Ning Ma Feng Gao Ligang Song Xuan Sun Lian Liu Yiming Deng Xiaoqing Li Bo Wang Gaoting Ma Yilong Wang Yongjun Wang Zhongrong Miao Dapeng Mo ANGEL-ACT Source Type: research
Association of plaque enhancement on vessel wall MRI and the phosphodiesterase 4D variant with stroke recurrence in patients with symptomatic intracranial atherosclerosis
CONCLUSION: Plaque enhancement on VW-MRI and the presence of the PDE4D83 variant are associated with ischemic stroke recurrence in subjects with symptomatic ICAS.PMID:35420310 | DOI:10.1007/s00234-022-02948-3
Source: Atherosclerosis - April 14, 2022 Category: Cardiology Authors: Chuanhui Xu Jun Qin Jinhui Yu Yan Sun Dongmin Hu Gang Wu Yang Li Source Type: research
Potential association between bacterial infections and ischemic stroke based on fifty case-control studies: A systematic review and meta-analysis
CONCLUSIONS: In this meta-analysis, a significant relationship was observed between infection by three bacteria such as C. pneumoniae, H. pylori, and M. tuberculosis with the occurrence of ischemic stroke. Furthermore, due to the similarity between TLRVYK domain in β2-glycoprotein-I and TLRVYK peptide in various of microorganisms, produced antibodies against pathogens interact with β2-glycoprotein-I, hence the cross-reaction phenomenon increases the positive relationship between infectious diseases and ischemic stroke.PMID:35592534 | PMC:PMC9112101 | DOI:10.1016/j.nmni.2022.100980
Source: Atherosclerosis - May 20, 2022 Category: Cardiology Authors: M Keikha M Karbalaei Source Type: research
Dynamic changes of carotid atherosclerosis and their relations with stroke recurrence in patients with stroke or transient ischemic attack
CONCLUSION: Plaque progression occurred in 46% of stroke or TIA patients. Plaque progression was significantly associated with clinical stroke recurrence. Plaque regressed in 6.5% of patients. Patients with regression were younger than those without.PMID:35996235 | DOI:10.2174/1567202619666220822141804
Source: Atherosclerosis - August 23, 2022 Category: Cardiology Authors: Eun-Ye Lim A-Hyun Cho Source Type: research
Outcomes of Mild Stroke and High-risk Transient Ischemic Attack in Current Clinical Practice
CONCLUSION: Implementation of the up-to-date standard care in clinical practice might bring good clinical outcomes to the patients with mild stroke and high-risk TIA.PMID:36130531 | DOI:10.1159/000526969
Source: Atherosclerosis - September 21, 2022 Category: Cardiology Authors: Apiluk Wesanonthawech Pornpatr A Dharmasaroja Source Type: research
Stroke genetics informs drug discovery and risk prediction across ancestries
Nature. 2022 Sep 30. doi: 10.1038/s41586-022-05165-3. Online ahead of print.ABSTRACTPrevious genome-wide association studies (GWASs) of stroke - the second leading cause of death worldwide - were conducted predominantly in populations of European ancestry1,2. Here, in cross-ancestry GWAS meta-analyses of 110,182 patients who have had a stroke (five ancestries, 33% non-European) and 1,503,898 control individuals, we identify association signals for stroke and its subtypes at 89 (61 new) independent loci: 60 in primary inverse-variance-weighted analyses and 29 in secondary meta-regression and multitrait analyses. On the basi...
Source: Atherosclerosis - September 30, 2022 Category: Cardiology Authors: Aniket Mishra Rainer Malik Tsuyoshi Hachiya Tuuli J ürgenson Shinichi Namba Daniel C Posner Frederick K Kamanu Masaru Koido Quentin Le Grand Mingyang Shi Yunye He Marios K Georgakis Ilana Caro Kristi Krebs Yi-Ching Liaw Felix C Vaura Kuang Lin Bendik Sla Source Type: research
Is Composition of Brain Clot Retrieved by Mechanical Thrombectomy Associated with Stroke Aetiology and Clinical Outcomes in Acute Ischemic Stroke?-A Systematic Review and Meta-Analysis
Conclusions: This meta-analysis found that fibrin composition is significantly higher in strokes of cardioembolic and cryptogenic origin, and that red blood cell content is positively associated with the hyperdense middle cerebral artery sign and better reperfusion outcomes. Important advances to stroke clinical workup can be derived from these findings, in which many aspects of stroke workflow remain to be optimised. As data are still limited in terms of the association of various thrombus components with stroke aetiology as well as a standardised method of analysis, further studies are required to validate these findings...
Source: Atherosclerosis - October 24, 2022 Category: Cardiology Authors: Joanna Huang Murray C Killingsworth Sonu M M Bhaskar Source Type: research
ADAMTS-13 activity in stroke of known and unknown cause: Relation to vascular risk factor burden
CONCLUSION: ADAMTS-13 activity is inversely correlated with the number of vascular risk factors across different stroke etiologies. Further study is warranted to establish ADAMTS-13 as a mediator of cerebrovascular risk.PMID:36703637 | PMC:PMC9871749 | DOI:10.3389/fneur.2022.1045478
Source: Atherosclerosis - January 27, 2023 Category: Cardiology Authors: Gerrit M Grosse Andrei Leotescu Jan-Thorben Sieweke Sonja Schneppenheim Ulrich Budde Nora L Ziegler Saskia Biber Maria M Gabriel Johanna Ernst Ramona Schuppner Ralf Lichtinghagen Udo Bavendiek Julian Widder Karin Weissenborn Source Type: research
Circulating macrophage colony-stimulating factor levels and stroke: A Mendelian randomization study
CONCLUSIONS: This study provides evidence that genetically predicted higher CSF1 levels was associated with higher risk of any ischemic stroke, LAS, and CES. Whether targeting CSF1 or its receptors can reduce the risk of ischemic stroke needs further study.PMID:36780760 | DOI:10.1016/j.jstrokecerebrovasdis.2023.107050
Source: Atherosclerosis - February 13, 2023 Category: Cardiology Authors: Liping Cao Dandan Liu Ville Karhunen Yi Ren Dan Ye Jie Gao Dipender Gill Mengmeng Wang Source Type: research
