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Total 49 results found since Jan 2013.

Overrepresentation of isolated verbal repetition deficits in aphasic males with stroke: A systematic literature review and meta-analysis (P4.211)
Conclusions:Chronic isolated repetition deficits are more prevalent in men than in women. This finding is clinically relevant because of repetition’s role in language acquisition and recovery, being a main mechanism by which children learn to speak and a major resource in language rehabilitation techniques.Disclosure: Dr. Pertierra has nothing to disclose. Dr. Torres Prioris has nothing to disclose. Dr. Dávila has nothing to disclose. Dr. Allegri has nothing to disclose. Dr. Berthier has received personal compensation for activities with Pfizer/Eisai, Merz, Lundbeck, GlaxoSmithKline, Eli Lilly, Novartis and Ja...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Pertierra, L., Prioris, M. J. T., Davila, M. G., Allegri, R., Torres, M. B. Tags: Behavioral and Cognitive Neurology: Language Source Type: research

Development and Feasibility of a Canine Endovascular Reversible Middle Cerebral Artery Occlusion Stroke Model: a Novel anterior circulation approach (P1.267)
Conclusions:Here we report the successful development of an endovascular reversible MCAo model in the canine by an anterior circulation approach. A learning curve is seen in the successful implementation of this model, as shown by our results.Disclosure: Dr. Guada has nothing to disclose. Dr. Ramdas has nothing to disclose. Dr. Atchaneeyasakul has nothing to disclose. Dr. Watanabe has nothing to disclose. Dr. Sidani has nothing to disclose. Dr. Yavagal has received personal compensation for activities with Medtronic and Guidepoint as a consultant.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Guada, L., Ramdas, K., Atchaneeyasakul, K., Watanabe, M., Sidani, C., Yavagal, D. Tags: Genetic Stroke Syndromes, Biomarkers, and Translational/Basic Research Source Type: research

Improving Cognitive Screening Accuracy and Efficiency II: Application for Parkinsons disease (P6.307)
Conclusions:We demonstrate rapid, precise measurement of motor and cognitive components in PD that affords high classification accuracy in individuals performing in the normal range on the MMSE, offering an opportunity for sensitive, efficient cognitive monitoring.Disclosure: Dr. Davis has received personal compensation for activities with Digital Cognition Technologies, Inc. Dr. Davis has received royalty payments from Digital Cognition Technologies, Inc. Dr. Davis holds stock and/or stock options in Digital Cognition Technologies, Inc. Dr. Davis has received research support from Foxconn Corp. Dr. Souillard-Mandar has re...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Davis, R., Souillard-Mandar, W., Au, R., Penney, D. Tags: Behavioral and Cognitive Neurology: Diagnostic Testing Source Type: research

Improving Cognitive Screening Accuracy and Efficiency for Minimally Impaired Individuals (P6.308)
Conclusions:We demonstrate rapid detection of subtle cognitive impairment in individuals performing in the normal range on a widely used screening tool, offering an opportunity for sensitive, efficient cognitive screening.Disclosure: Dr. Davis has received personal compensation for activities with Digital Cognition Technologies, Inc. Dr. Davis has received royalty payments from Digital Cognition Technologies, Inc. Dr. Davis holds stock and/or stock options in Digital Cognition Technologies, Inc. Dr. Davis has received research support from Foxconn Corp. Dr. Souillard-Mandar has received personal compensation for activities...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Davis, R., Souillard-Mandar, W., Au, R., Penney, D. Tags: Behavioral and Cognitive Neurology: Diagnostic Testing Source Type: research

Simulation-Based Medical Education in Acute Neurologic Emergencies (P1.059)
Conclusions:Our data confirms the utility of SBME in acute neurologic disorders to improve resident confidence, clinical knowledge, teamwork, and communication skills. This experience allows us to improve future simulations by focusing on updated guidelines and a detailed analysis of resident performance.Disclosure: Dr. Ansari has nothing to disclose. Dr. Swor has nothing to disclose. Dr. Moreno has nothing to disclose. Dr. Park has nothing to disclose. Dr. Holder has nothing to disclose. Dr. Koo has nothing to disclose. Dr. Poblete has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Ansari, M., Swor, D., Moreno, G., Park, K., Holder, D., Koo, B., Poblete, R. Tags: Undergraduate Medical Education Research Source Type: research

Aphemia: A rare presentation of an acute infarct (P3.277)
Conclusions:Aphemia, or apraxia of speech, is a rare presentation of dominant inferior frontal gyrus infarction. Aphemia is primarily a disorder of articulation, whereas aphasia is a disorder of language. This patient lost her ability to produce speech but was able to comprehend and write fluently. Her deficit did not fit a classic aphasia pattern but rather represented an inability to voluntarily control her oral muscles, resulting in a transient apraxia of the muscles of articulation, chewing, and deglutition. Very few cases of acute aphemia due to stroke are described, all localized to the dominant inferior frontal gyru...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Stachyra, J., Davalos-Balderas, A., Lee, J., Kass, J. Tags: Cerebrovascular Disease Case Reports II Source Type: research

CSF biomarkers suggest a strong role of glial inflammation in the pathogenesis of frontotemporal dementia (P6.104)
Conclusions:FTD features increased YKL-40, sTREM2 and NfL, a profile that distinguishes it from controls and AD. The dynamic relationship between CSF neuroinflammatory and injury biomarkers and disease severity support a strong role for neuroinflammation in the progression of FTD.Study Supported by:NIH 2T32 AG023481, National Institutes of Health, 4-Repeat Tauopathy Neuroimaging Initiative (4RTNI, AG03879); the National Center for Advancing Translational Science (NCATS) and National Institute of Neurological Disorders and Stroke (NINDS), Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL, NS09208...
Source: Neurology - April 17, 2017 Category: Neurology Authors: -Martinez, J. R., Calvet, M. S., Karydas, A., Kleinberger, G., Kramer, J., Rosen, H., Rabinovici, G., Miller, B., Fagan, A., Haass, C., Boxer, A. Tags: Aging and Dementia Poster Discussion Session: Novel Approaches in Neurodegenerative Diseases: Genetics, Biomarkers, and Therapies Source Type: research

Transcranial direct current stimulation for children with perinatal stroke and hemiparesis
Conclusion: tDCS trials appear feasible and safe in hemiparetic children. Lack of change in objective motor function may reflect underdosing of therapy. Marked gains in subjective function with tDCS warrant further study. ClinicalTrials.gov identifier: NCT02170285. Classification of evidence: This study provides Class II evidence that for children with perinatal stroke and hemiparetic cerebral palsy, the addition of tDCS to moderate-dose motor learning therapy does not significantly improve motor function as measured by the AHA.
Source: Neurology - January 15, 2017 Category: Neurology Authors: Kirton, A., Ciechanski, P., Zewdie, E., Andersen, J., Nettel-Aguirre, A., Carlson, H., Carsolio, L., Herrero, M., Quigley, J., Mineyko, A., Hodge, J., Hill, M. Tags: Childhood stroke, Clinical trials Randomized controlled (CONSORT agreement), All Rehabilitation, Plasticity, TMS ARTICLE Source Type: research

Combining rTMS and CIMT: A "one-size-fits-all" therapy for congenital hemiparesis?
In the past decade, we have experienced dramatic progress in the treatment of children with congenital hemiparesis.1 One important step was the introduction of intensive rehabilitation approaches based on principles of motor learning and neuroplasticity, such as constraint-induced movement therapy (CIMT) and intensive bimanual training. Often these approaches are implemented in socially stimulating "camp" environments.
Source: Neurology - May 1, 2016 Category: Neurology Authors: Staudt, M., Gordon, A. M. Tags: All Rehabilitation, Plasticity, TMS, Pediatric stroke; see Cerebrovascular Disease/ Childhood stroke EDITORIALS Source Type: research

Brain stimulation and constraint for perinatal stroke hemiparesis: The PLASTIC CHAMPS Trial
Conclusions: Hemiparetic children participating in intensive, psychosocial rehabilitation programs can achieve sustained functional gains. Addition of CIMT and rTMS increases the chances of improvement. Classification of evidence: This study provides Class II evidence that combined rTMS and CIMT enhance therapy-induced functional motor gains in children with stroke-induced hemiparetic cerebral palsy.
Source: Neurology - May 1, 2016 Category: Neurology Authors: Kirton, A., Andersen, J., Herrero, M., Nettel-Aguirre, A., Carsolio, L., Damji, O., Keess, J., Mineyko, A., Hodge, J., Hill, M. D. Tags: All Rehabilitation, Plasticity, TMS, Pediatric stroke; see Cerebrovascular Disease/ Childhood stroke ARTICLE Source Type: research

Simulation of Neurological Emergencies for Milestones-Based Learning and Assessment (P2.357)
CONCLUSIONS: Simulations of neurological emergencies can increase resident comfort in several aspects of care and can be used to reliably assess resident competence based on the Neurology Milestones.Disclosure: Dr. Loomis has nothing to disclose. Dr. Robeson has nothing to disclose. Dr. DiCapua has received personal compensation for activities as a consultant. Dr. Dodge has nothing to disclose. Dr. Evans has nothing to disclose. Dr. Moadel has nothing to disclose. Dr. Cruz has nothing to disclose. Dr. Moeller has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Loomis, C., Robeson, K., DiCapua, D., Dodge, K., Evans, L., Moadel, T., Cruz, L., Moeller, J. Tags: Education Research: Graduate Medical Education Source Type: research

Incorporating Quality Improvement into the Third-Year Neurology Curriculum (P2.380)
Conclusions: We present an initiative that gives medical students quality improvement experience and may help reduce patient readmissions. Data analysis is ongoing with final results anticipated in Spring 2016.Disclosure: Dr. Liyanage-Don has nothing to disclose. Dr. Hohler has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Liyanage-Don, N., Hohler, A. Tags: Research Methodology and Education: Patient Safety and Quality Source Type: research

Identification of ADHD in Youth with Epilepsy (P3.257)
Conclusion. Inclusion of behavior rating scales as part of routine care in neurology clinics may be the most efficient and cost effective way to identify ADHD in youth with epilepsy.Disclosure: Dr. Kral has nothing to disclose. Dr. Lally has nothing to disclose. Dr. Boan has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Kral, M., Lally, M., Boan, A. Tags: Child Neurology and Developmental Neurology: Epilepsy, Hypoxia, and Stroke Source Type: research

Prognostic Risk Profiles for Dementia: A Machine Learning Approach (P1.091)
Conclusions: These results suggest that vascular factors may play a greater role in dementia pathogenesis than currently thought. Furthermore, using this method we were able to achieve prediction accuracies that compare favorably with the existing literature.Disclosure: Dr. Morgenstern has nothing to disclose. Dr. Daley has nothing to disclose. Dr. Hachinski has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Morgenstern, J., Daley, M., Hachinski, V. Tags: Epidemiology of Aging and Dementias Source Type: research

Kinematic and Kinetic Outcome of Robot Assisted Neurorehabilitation in Chronic Moderate-to-Severe Hemiparetic Stroke (P3.298)
Conclusions: RT+TTT was not significantly different from RT alone, suggesting that TTT did not interfere with motor learning conferred by RT. Study Supported by: American Academy of Neurology (AAN) and the VA Department of Research and Development VA Merit Award B6935RDisclosure: Dr. Iqbal has nothing to disclose. Dr. Conroy has nothing to disclose. Dr. Roy has nothing to disclose. Dr. Bever has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Iqbal, T., Conroy, S., Roy, A., Bever, C. Tags: Neurorehabilitation Source Type: research